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Body Mass Index and Subsequent Risk of Hypertension, Hyperglycemia and Hypercholesterolemia in Health Checkup Examinees

건강검진 수검자들의 비만도와 고혈압, 고혈당 및 고콜레스테롤혈증과의 관련성

  • Wang, Seong-Bae (Department of Preventive Medicine and Public Health, Graduate School of Chungnam National University) ;
  • Cho, Young-Chae (Department of Preventive Medicine and public Health, Chungnam National University School of Medicine and Research Institute for Medical Sciences)
  • 왕성배 (충남대학교 대학원 예방의학과) ;
  • 조영채 (충남대학교 의학전문대학원 예방의학교실 및 의학연구소)
  • Received : 2011.04.14
  • Accepted : 2011.06.09
  • Published : 2011.06.30

Abstract

This study was conducted to clarify relationships between BMI and the incidence of hypertension, hyperglycemia and hypercholesterolemia among health checkup examinees. The study sample consists of 3,402 adults aged 30s - 60s years, who underwent health check-up at a university hospital. during the Jan. 2007 to Dec. 2008.As a results, blood pressure level at the base line, ORs(95% CI) of hypertension compared with BMI category of 18.5-22.9(normal group) were 1.7(1.2-3.8) for obesity group I, and 2.9(1.7-6.2) for obesity group II. After adjusting for age and sex, ORs(95% CI) of hypertension compared with BMI category of normal group were 1.3(1.0-1.7) for obesity group I, 1.8(1.3-2.4) for obesity group II. Serum total cholesterol level at the base line, ORs(95% CI) of hypercholesterolemia compared with BMI category of normal group were 1.7(1.5-4.9) for obesity group I, and 2.8(1.8-5.3) for obesity group II. After adjusting for age and sex, ORs(95% CI) of hypercholesterolemia compared with BMI category of normal group were 1.5(1.1-1.9) for obesity group I, and 2.3(1.7-3.1) for obesity group II.

본 연구는 건강검진 수검자들의 BMI 구분에 따른 혈압, 혈당 및 총콜레스테롤치의 분포를 알아보고, BMI와 고혈압, 고혈당 및 고콜레스테롤혈증 발생과의 관련성을 알아보고자 2007년 1월부터 2008년 12월까지 한 대학병원 건강검진센터에서 종합건강검진을 받았던 30세 이상의 일반 성인 3,402명을 대상으로 비만도와 고혈압, 고혈당 및 고콜레스테롤혈증과의 관련성을 분석하였다. 연구결과고혈압 발생의 위험비는 BMI가 정상인 군에 비해 비만(I)군에서 1.7배, 비만(II)군에서 2.9배 높았으며, 성별 및 연령을 보정한 경우에서도 각각 1.3배, 1.8배 높게 나타났다. BMI와 고콜레스테롤혈증 발생의 위험비에서는 BMI가 정상인 군에 비해 비만(I)군에서 1.7배, 비만(II)군에서 2.8배 높았으며, 성별 및 연령을 보정한 경우에서도 각각 1.5배, 2.3배 높게 나타났다.

Keywords

References

  1. World Health Organization. Obesity: Preventing and Managing the Global Epidemic. WHO: Geneva, 1998.
  2. Eckel RH. Obesity: Mechanisms and Clinical Management. Philadelphia: Lippincott Williams & Wilkins; 2003.
  3. WHO. Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation on obesity. Geneva; World Health Organization 2000.
  4. Ministry for Health Welfare and Family Affairs. Korea National Health and Nutrition Examination Survey - 2007, Ministry for Health Welfare and Family Affairs. 2008.
  5. Kim NS, Moon OR, Kang JH, Lee SY, Jeong BG, Lee SJ, Yoon TH, Hwang KH. Increasing prevalence of obesity related disease for Korean associated with overweight and obesity. Korean J Prev Med 34(4) pp.309-315, 2001.
  6. Jee SH, Sull JW, Park J, Lee SY, Ohrr H, Guallar E, et al. Body-mass index and mortality in Korean men and women. N Engl J Med 355(8) pp.779-787, 2006. https://doi.org/10.1056/NEJMoa054017
  7. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288(14) pp.1723-1727, 2002. https://doi.org/10.1001/jama.288.14.1723
  8. Kereiakes DJ, Willerson JT. Metabolic syndrome epidemic. Circulation 108 pp.1552-1553, 2003. https://doi.org/10.1161/01.CIR.0000093203.00632.2B
  9. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, et al. Prevalence of obesity, diabetes, and obesity related health risk factors, 2001. JAMA 289(1) pp.76-79, 2003. https://doi.org/10.1001/jama.289.1.76
  10. Dyer AR, Stamler J, Shekelle RB. Relative weight and blood pressure in four Chicago epidemiologic studies. J Chronic Dis 35 pp.897-908, 1982. https://doi.org/10.1016/0021-9681(82)90121-7
  11. Beaglehole R, magnus P. the search for new factors for coronary heart disease: occupational therapy for epidemiologists? Int J Epidemiol 31 pp.1117-1122, 2002. https://doi.org/10.1093/ije/31.6.1117
  12. Hartz AJ, Rupley DC, Kalkohoff RD. Relationship of obesity to diabetes:influence of obesity level and body fat distribution. Prev Med 1983; 12:351-357 https://doi.org/10.1016/0091-7435(83)90244-X
  13. Solomon CG, Manson JE. Obeity and mortality: review of the epidemiologic data. Am J Clin nutr 66(4) pp.1044S-1050S, 1997.
  14. Yao CH, Slattery MI, Jacobs DR. Anthropometric predictors of coronary heart disease and total mortality: findings from the US Railroad Study. Am J Epidemiol 134 pp.1278-1289, 1991.
  15. WHO. The Asia-Pacific Perspective:Redefining Obesity and Its Treatment. Sydney, Australia, Health Communications Australia Pty Ltd, 2000.
  16. Ministry for Health Welfare and Family Affairs. Korea National Health and Nutrition Examination Survey pp.106-126, 2004.
  17. Park YH, Rhee CS, Lee YC. Distribution Patterns of Serum Lipids by Degree of Obesity and Blood Pressure in Korean Adults. Korean J perinatology 3(2) pp.165-180, 1993
  18. Cho YC, Song IS. Charastics of BMI, blood pressure and serum lipid levels according to age and health behavior in industrial workers. J Korean Public Health Assoc 26(2) pp.143-151, 2000.
  19. Kim ES, Kim KH, Cho YC. Prevalence of clustering of coronary risk factors in health checkup examinees. Journal of The Korea Academia-Industrial Cooperation Society 10(3) pp.625-633, 2009. https://doi.org/10.5762/KAIS.2009.10.3.625
  20. Weinsier RL, Fuchs RJ, Kay TD, Triebwasser JH, Lancaster MC: Body fat: Its relationship to coronary heart disease, blood pressure, lipids and other risk factors measured in a large male population. Am J Med 61 pp.815-24, 1976. https://doi.org/10.1016/0002-9343(76)90405-8
  21. Kannel WB, Gordon T, Castelli WP. Obesity, lipids and glucose intolerance, the Framingham study. Am J Clin Nutr 32 pp.1238-1245, 1979.
  22. Baumgartner RN, Roche AF, Chumlea WC. Fatness and far patterns:Associations with plasmalipids and blood pressures in adults, 18 to 57 years of age. Am J Epidemiol 126(4) pp.614-628, 1987.
  23. Freedman DS, William HD, Srinivasan SR, Bereson GS. The relation of overweight to cardiovascular risk factors among children and adolescents: The Bogalusa heart study. Pediatrics 103(6) pp.1175-1182, 1999. https://doi.org/10.1542/peds.103.6.1175
  24. Vos LE, Oren A, Uiterwaal C, Gorrssen WHM, Grobbee DE, Bots ML. Adolescent blood pressure and blood pressure tracking into young adulthood are related to subclinical atherosclerosis; The atherosclerosis risk in young adults(ARYA) study. Am J Hypretens 16 pp.549-555, 2003. https://doi.org/10.1016/S0895-7061(03)00857-4
  25. Ishikawa-Takata K, Ohta T, Moritaki K. Obesity weight change and risks for hypertension, diabetes, and hypercholesterolemia in Japanese men. Eur J Clin Nutr 56 pp.601-607, 2002. https://doi.org/10.1038/sj.ejcn.1601364
  26. Yamagishi K, Hosoda T, Sarenchi T, Mori K, Tomita H, Nishimura A, Tanagawa T, Iso H. Body mass index and subsequent risk of hypertension, diabets and hypercholesterolemia in a population-based sample of Japanese. Japanese J of Public Health 50(11):1050-1057, 2003.

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