DOI QR코드

DOI QR Code

The quantitative analysis of Diffusion Weighted Imaging in Breast MRI

유방 MRI 검사에서 확산강조영상의 정량적 분석

  • Cho, Jae-Hwan (Department of Radiological Science, Gyeonesan University College) ;
  • Kim, Hyeon-Ju (Department of Radiology, Soonchunhyang University. Hospital) ;
  • Hong, Yin-Sik (Department of Computer Science and Soonchunhyang University) ;
  • Lee, Hae-Kag (Department of Computer Science and Soonchunhyang University)
  • 조재환 (경산1대학 방사선과) ;
  • 김현주 (순천향대학교 부천병원 영상의학과) ;
  • 홍인식 (순천향대학교 컴퓨터공학과) ;
  • 이해각 (순천향대학교 컴퓨터공학과)
  • Received : 2011.04.18
  • Accepted : 2011.06.14
  • Published : 2011.06.30

Abstract

The purpose of this study was to examine the usefulness of diffusion weighted images in breast MRI by performing a quantitative comparative analysis in patients diagnosed with DCIS. On a 3.0T MR scanner, diffusion weighted images and ADC map images were obtained from 20 patients histologically diagnosed with ductal carcinoma in situ (DCIS). The findings from the quantitative image analysis are the following: The diffusion weighted images showed higher SNR and CNR at the lesion area. In addition, the ADC values were lower at the lesion area.

유방암중 관상피 내암으로 진단 받은 환자를 대상으로 확산강조 영상을 정량적으로 비교 분석하여 확산강조영상의 효과와 유용성을 고찰 해보고자 한다. 조직학적으로 관상피 내암으로 진단 받은 환자 20명을 대상으로 3.0T MR scanner를 이용하여 확산강조영상과 ADC map 영상을 획득하였다. 정량적 분석 결과 병변 부위와 정상부위의 신호대 잡음비와 대조도대 잡음비는 병변 조직에서 높은 신호대 잡음비와 대조도대 잡음비를 보였으며 병변 부위와 정상부위의 현성확산계수는 병변 조직에서 낮은 현성확산계수를 보였다.

Keywords

References

  1. Munetomo E, Akito M, Goi S, et al, "Invasive Ductal Carcinoma of the Breast with a Predominant Intraductal Component," Japanese Journal of Clinical Oncology, Vol. 22, No. 2, pp.84-91, 1992.
  2. Morris EA, "Breast cancer imaging with MRI," Radiol Clin North Am, Vol. 40, No. 2, pp.443-466, 2002. https://doi.org/10.1016/S0033-8389(01)00005-7
  3. Bear HD, "Image-guided breast biopsy-how, when, and by whom?" J Surg Oncol, Vol. 67, No. 3, pp.1-5, 1998. https://doi.org/10.1002/(SICI)1096-9098(199801)67:1<1::AID-JSO1>3.0.CO;2-F
  4. Fornage BD, Faroux M J, Simatos A, "Breast masses: US-guided fine-needle aspiration biopsy," Radiology, Vol. 162, No. 3, pp.409-414, 1987. https://doi.org/10.1148/radiology.162.2.3541029
  5. Sneige N, Fornage BD, Saleh G, "Ultrasound-guided fine-needle aspiration of nonpalpable breast lesion: Cystology and histologic findings," Am J Clin Pathol, Vol. 102, No. 4, pp.98-101, 1994. https://doi.org/10.1093/ajcp/102.1.98
  6. Boetes C, Mus RD, Holland R, et al, "Breast tumors: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent," Radiology, Vol. 197, No. 4, pp.743-747, 1995. https://doi.org/10.1148/radiology.197.3.7480749
  7. Malur S, Wurdinger S, Moritzet A, et al, "Comparison of written reports of mammography, sonography andmagnetic resonance mammography for preoperative evaluation of breast lesions, with special emphasis on magnetic resonance mammography," Breast Cancer Res, Vol. 3, No. 2, pp.55-60, 2001. https://doi.org/10.1186/bcr271
  8. Teifke A, Behr O, Schmidt M, Victor A, Vomweg TW, Thelen M, et al, "Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis," Radiology, Vol. 239, No. 4, PP, 351-360, 2006. https://doi.org/10.1148/radiol.2392050205
  9. Kuhl CK, Schrading S, Leutner CC, Morakkabati-Spitz N, Wardelmann E, Fimmers R, et al, "Mammography, breast ultrasound and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer," J Clin Oncol, Vol. 23, No. 1, pp. 8469-8476, 2005. https://doi.org/10.1200/JCO.2004.00.4960
  10. Albers GW, "Diffusion-weighted MRI for evaluation of acute stroke," Neurology Vol. 51, No. 3, pp.S47-S49, 1998. https://doi.org/10.1212/WNL.51.3_Suppl_3.S47
  11. Abou-El-Ghar ME, El-Assmy A, Refaie HF, and El-Diasty T,"Bladder cancer: diagnosis with diffusion-weighted MR imaging in patients with gross hematuria," Radiology, Vol. 251, No. 3, pp. 415-421, 2009. https://doi.org/10.1148/radiol.2503080723
  12. Lee KC, Moffat BA, Schott AF, Layman R, Ellingworth S, Juliar R, et al, "Prospective early response imaging biomarker for neoadjuvantbreast cancer chemotherapy," Clin Cancer Res, Vol. 13, No. 1, pp.443-450, 2007. https://doi.org/10.1158/1078-0432.CCR-06-1888
  13. Guo Y, Cai YQ, Cai ZL, Gao YG, An NY, Ma L, et al. "Differentiation of clinically benign and malignant breast lesions using diffusion-weighted imaging," J Magn Reson Imaging, Vol. 16, pp.172-178, 2002. https://doi.org/10.1002/jmri.10140
  14. Yoshikawa MI, Ohsumi S, Sugata S, Kataoka M, Takashima S, Kikuchi K, et al. "Comparison of breast cancer detection by diffusion-weighted magnetic resonance imaging and mammography," Radiat Med, Vol. 25, pp.218-223, 2007. https://doi.org/10.1007/s11604-007-0128-4
  15. Kuroki-Suzuki S, Kuroki Y, Nasu K, Nawano S, Moriyama N, and Okazaki M, "Detecting breast cancer with non-contrast MR imaging: combining diffusion-weighted and STIR imaging," Magn Reson Med Sci, Vol. 6, pp.21-27, 2007. https://doi.org/10.2463/mrms.6.21

Cited by

  1. A Study on Optimized MRI Fat-Saturation Technique for Brachial Plexus Patients : Focused on SPAIR and STIR Fat-Saturation vol.8, pp.5, 2014, https://doi.org/10.7742/jksr.2014.8.5.271
  2. 유방암의 확산텐서 자기공명 영상에서 유도된 확산 지표(FA, ADC) 값의 연관성 분석 vol.12, pp.6, 2018, https://doi.org/10.7742/jksr.2018.12.6.755