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Risk Factors for Oral Cancer in Northeast Thailand

  • Loyha, Kulchaya (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
  • Vatanasapt, Patravoot (Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University) ;
  • Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
  • Parkin, Donald Maxwell (Clinical Trials Service Unit and Epidemiological Studies Unit, University of Oxford)
  • Published : 2012.10.31

Abstract

Oral cancer is a common site of head and neck cancer, and is relatively frequent in Northeast Thailand. The objective of this hospital-based, case-control study was to determine associations with risk factors. A total of 104 oral cancer cases diagnosed between July 2010 and April 2011 in 3 hospitals were matched with control subjects by age, sex and hospital. Data were collected by personal interview. There were significant associations between oral cancer and tobacco smoking (OR=4.47; 95%CI=2.00 to 9.99), alcohol use among women (OR=4.16; 95%CI=1.70 to 10.69), and betel chewing (OR=9.01; 95%CI=3.83 to 21.22), and all three showed dose-response effects. Smoking is rare among Thai women (none of the control women were smokers), but betel chewing, especially among older women, is relatively common. We did not find any association between practicing oral sex and oral cancer.

Keywords

References

  1. Applebaum MK, Furniss SC, Zeka A, et al (2007). Lack of association of alcohol and tobacco with HPV16 - associated head and neck cancer. J Natl Cancer Inst, 99, 1801-10. https://doi.org/10.1093/jnci/djm233
  2. Attasara P, Buasom R (2010). Hospital-based Cancer Registry 2009. Rumthai Press, Thailand, 5-6.
  3. Chung C-H, Yang Y-H, Wang T-Y, et al (2005). Oral precancerous disorders associated with areca quid chewing, smoking, and alcohol drinking in southern Taiwan. J Oral Pathol Med, 34, 460-6. https://doi.org/10.1111/j.1600-0714.2005.00332.x
  4. D'Souza G, Kreimer AR, Viscidi R, et al (2007). Case-control study of human papillomavirus and oropharyngeal cancer. The New England J Med, 356, 1944-56. https://doi.org/10.1056/NEJMoa065497
  5. Ferlay J, Shin HR, Bray F, et al (2008). Estimated new cancer cases and deaths worldwide for leading cancer sites: section of cancer information, Int Agency for Res on Cancer, VOL?, 69372.
  6. Ferlay J, Shin HR, Bray F, Mathers C, Parkin DM (2010). GLOBOCAN 2008 V1.2. GLOBOCAN 2008 V1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 (Internet). globocan.iarc.fr.
  7. Heck JE, Berthiller J, Vaccarella S, et al (2010). Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Int J Epidemiol, 39, 166-81. https://doi.org/10.1093/ije/dyp350
  8. International Agency for Research on Cancer (2004). Betelquid and areca-nut hewing and some areca-nut derived Nitrosamines: IARC Monographs on the evaluation of carcinogenic risks to humans, JOURNAL?, 85, 11-8.
  9. International Agency for Research on Cancer (2004). Tobacco Smoke and Involuntary Smoking: IARC Monographs on the evaluation of carcinogenic risks to humans, 83, 14-6.
  10. Khuhaprema T, Srivatanakul P, Sriplung H, et al (2010). Cancer in Thailand (2001-2003). National Cancer Institute Department of Med Services Ministry of Public Hlth, 5, 11-5.
  11. Kreimer AR, Clifford GM, Boyle P, Franceschi S (2005). Humanpapillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev, 14, 467-75. https://doi.org/10.1158/1055-9965.EPI-04-0551
  12. Lambert R, Sauvaget C, de Camargo Cancela M, et al (2011). Epidemiology of cancer from the oral cavity and oropharynx. Eur J Gastroenterol Hepatol, 23, 233-41.
  13. Lin C-F, Wang J-D, Chen P-H, et al (2006). Predictors of betel quid chewing behavior and cessation patterns in Taiwan aborigines. BMC Public Hlth, 6, 271. https://doi.org/10.1186/1471-2458-6-271
  14. Simarak S, De Jong UW, Breslow N, et al (1977). Cancer of oral cavity, pharynx/larynx and lung in north Thailand: case-control study and analysis of cigar smoke. Br J Cancer, 36, 130-40. https://doi.org/10.1038/bjc.1977.163
  15. Vatanasapt P, Suwanrungruang K, Kamsa-Ard S, et al (2011). Epidemiology of oral and pharyngeal cancers in Khon Kaen, Thailand: a high incidence in females. Asian Pac J Cancer Prev, 12, 2505-8.
  16. Vatanasapt V, Sriamporn S, MacLennan R (1991). Contrasts in risk factors for cancers of the oral cavity and hypopharynx and larynx in Khon Kaen, Thailand. In: Varma (Ed).Oral Oncology Volume II, Proceedings of International Congress on Oral Cancer, pp 39-42. Delhi: MacMillan Ltd.

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  17. Amplification of EGFR and cyclin D1 genes associated with human papillomavirus infection in oral squamous cell carcinoma vol.34, pp.9, 2017, https://doi.org/10.1007/s12032-017-1010-6
  18. Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer vol.39, pp.2092-7193, 2017, https://doi.org/10.4178/epih.e2017009
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