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The research of pharmacological activation for Sanguisorbae Radix Fractions as cosmetic material

오이풀 뿌리 분획물의 화장품 소재로서의 약리활성 연구

  • 장영아 (대구한의대학교 화장품약리학과) ;
  • 여신일 (메가젠임플란트) ;
  • 이진태 (대구한의대학교 화장품약리학과)
  • Received : 2012.02.20
  • Accepted : 2012.03.16
  • Published : 2012.03.30

Abstract

Objectives : Sanguisorbae Radix(SO) is a plant in the family Rosaceae, which grows widely in open fields Korea. It has been used as traditional medicine for thousands of years, as a treatment for anti-inflammatory and it is widely used for throat infection, tonsilitis, conjuctivitis and lymphadentis. In this study, investigated skin antiaging and anti-bacterial by using SO fractions water, acetone and butanol, chloroform. Methods : The effects of anti-microbial on SO fractions and elastase inhibition activity, collagenase inhibition activity were experimented. Results : 1. The ethyl acetate fraction showed the strongest antimicrobial activity against Staphylococcus epidermidis. 2. The elastase inhibition rate and collagenase inhibition rate of the water fraction of SO was the highest other factions. Conclusions : From the above results, it was confirmed the SO has sufficient potentiality applying itself to industry and also SO can be utilized as antimicrobial natural materials and antiaging cosmetics.

Keywords

References

  1. Korea Institute of Patent Information. 2002(10); 0079594.
  2. Kim YG, Lee YH, Kang MK, Lee BH, Yun JK, Kim SB, and Kim CJ. Preparation of functional cosmetics containing $\beta$-carotene derived from recombinant Escherichiacoil and evaluationof antiwrinkle efficacyby clinical testing. Kor. J. Microbiol. Biotechnol. 2009;37;399-404.
  3. Kligman D. Cosmeveuticals. Dermatol Clin. 2000; 18;609-615. https://doi.org/10.1016/S0733-8635(05)70211-4
  4. Kwak YJ, Lee DH, Kim NM, and Lee JS. Screeing and extraction condition of anti-skin aging elastase inhibitor from medicina lplants. Kor. J. Medicinal Crop Sci. 2005;13(6);213-216.
  5. Mun JH, and Park CW. Flavonoid chemistry of Polygonum sect. Tovara (Polygonaceae) a systematic survey. Pl. Syst. Evol. 1995;196:153. https://doi.org/10.1007/BF00982956
  6. Kwak JH, Kim YH, Chang HR, Choi BW, Park CW, and Han YH Inhibitory effect of gardenia fruit extracts on tyrosinase activity and melanogenesis. Kor J Biotechnol Bioeng. 2004;19;437-440.
  7. Kwak JH, Seo UK, and HanYH. Inhibitory effect of Mugwork extracts on tyrosinase activity. Kor. J. BiotechnolBioeng. 2001;16;220-223.
  8. Choi WY, Chun HJ, Lee JH, and Baek SH. Effect of methanol extract from Cornis fructus on melanogenesis. Kor J Pharmacogn. 2003;34; 70-74.
  9. Chun HJ, Choi WH, Baek SH, and Woo WH. Effect of Quercetin on melanogenesis in a melanocyte cells. Kor J Pharmacogn. 2002;33;245-251.
  10. Kang BS, Ko UC, Kim SH, No SH, Shin YB, Song HJ, Shin MG, Ann DG, Lee SI, Lee YJ, Lee TH. Collaboration with a national college of oriental medicine herbology professor association. In Herbology. 1994;392-393.
  11. Son KJ, Lee SA, Lee G D, Kim YS, Jeon JG, Chang KY. Effects of crude Sanguisorbaofficinalis L. extract on the growth and the adherence to hydroxyapatite beads of mutans streptococci. The Journal of the Korean academy of dental health. 2004;28(1);97-104.
  12. Ryu MJ, Rim YS, Choi DI, Lee SY. Anti-fungal Activity Against Malasseziafurfur and Antiinflammatory Activity in RAW264.7 Cells of the Sanguisorbaofficinalis Extracts. Journal of Korean Beauty Society. 2011;225-232.
  13. Cannell RJ, Kellam SJ, Owsianka AM, and Walker JM. Results of a large scale screen of microalgae for the production of protease inhibitors. Planta Medica. 1987;54(1);4-10. https://doi.org/10.1055/s-2006-962317
  14. Wunsch E, and Heindrich HG. Zur quantitativen Bestimmung der Kollagenase. Hoppe-Seyler's Zeitschrift fur physiologische chemie. 1963;333: 149-151. https://doi.org/10.1515/bchm2.1963.333.1.149
  15. Lee SY, An JH, and Cho HY. Isolation and characterization of MMP-1 inhibitor Peptide from Crataegus pinnatifida bunge in fibroblast cell line HS68cells. J. Kor. Soc. Agric. Chem. Bio techno. 2003;46;60-65.
  16. Tsuji N, Moriwaki S, Suzuki Y, Takema Y, and Imokawa G. The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity. Photochemistry and Photobiology. 2001;74(2); 283-90. https://doi.org/10.1562/0031-8655(2001)074<0283:TROESB>2.0.CO;2
  17. Roth GJ, Siok CJ, and Ozols J. Structural characteristics of prostaglandin synthetase from sheep vesicular gland. Journal of Biological chemistry. 1980;255(4):1301-1304.
  18. Kim SN, Lee SH, Lee BK, and Jang IS. A compositions containing Anthriscus sylvestris Hoffmann extract or Petroselinum sativum Miller extract for external application having effects of improving skin wrinkle. Korea Institute of Patent Information. 2002;10;0079594.
  19. El-Domyati M, Attia S Saleh, F, Brown D, Birk DE, Gasparro F, Ahmad H, and Uitto J. Intrinsic aging vs. photoaging:a comparative histopathological, immunohistochemical, and ultrastructural study of skin. Experimental Dermatology. 2002;11(5);398-405. https://doi.org/10.1034/j.1600-0625.2002.110502.x

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