Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Clinicopathological Profile of Head and Neck Cancers in the Western Development Region, Nepal: A 4-Year Snapshot

  • Lasrado, Savita (Department of Otorhinolaryngology and Head and Neck Surgery, Father Muller Medical College) ;
  • Prabhu, Prashanth (Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College) ;
  • Kakria, Anjali (Department of Radiotherapy and Oncology, Kasturba Medical College) ;
  • Kanchan, Tanuj (Department of Forensic Medicine and Toxicology, Kasturba Medical College (Affiliated to Manipal University)) ;
  • Pant, Sadip (Department of Internal Medicine, University of Arkansas for Medical Sciences) ;
  • Sathian, Brijesh (Department of Community Medicine, Manipal College of Medical Sciences) ;
  • Gangadharan, P. (Cancer Registry, Amrita Institute of Medical Sciences and Research Centre) ;
  • Binu, V.S. (Department of Statistics, Manipal University) ;
  • Arathisenthil, S.V. (Department of Oral Pathology and Microbiology, Priyadarshini Dental College and Hospital) ;
  • Jeergal, Prabhakar A. (Department of Oral and Maxillofacial Pathology, AJ Institute of Dental Sciences) ;
  • Luis, Neil A. (Dental Surgeon in Private Practice) ;
  • Menezes, Ritesh G. (Department of Forensic Medicine and Toxicology, Srinivas Institute of Medical Sciences)
  • Published : 2012.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Regional cancer epidemiology is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the pattern of head and neck cancer in western Nepal and hence an attempt was here made to evaluate the situation based on hospital data, which provide the only source in the western region of Nepal. A clinicopathological analysis of head and neck cancers treated between 2003 and 2006 in Manipal Teaching Hospital affiliated to Manipal College of Medical Sciences, Pokhara, Western Development Region, Nepal was performed. A total of 105 head and neck cancer cases were identified with a male to female ratio of 1.8:1. The median ages of male and female patients were 62 and 64 years, respectively. Ninety-seven (92.4%) of the cancer patients were suffering from carcinoma, three (2.9%) had blastoma, three (2.9%) had sarcoma, and two (1.9%) had lymphoma. The majority (61.9%) of carcinoma cases were squamous cell carcinoma followed by anaplastic carcinoma (7.2%). Of the carcinoma cases, the most common site of primary lesion was larynx (19.6%), followed by the thyroid (14.4%), the tongue and hypopharynx with 10.3% cases each. Comparative analysis among males and females did not reveal any sex difference in type of head and neck cancers. The head and neck cancer pattern revealed by the present study provides valuable leads to cancer epidemiology in western Nepal and useful information for health planning and cancer control, and future research in western Nepal.

Keywords

References

  1. Baskota DK, Agrawal R, Prasad R, Sinha BK (2005). Distribution of malignancies in head and neck regions and their management. J Nep Med Assoc, 44, 68-72.
  2. Basu R, Mandal S, Ghosh A, Poddar TK (2008). Role of tobacco in the development of head and neck squamous cell carcinoma in an eastern Indian population. Asian Pac J Cancer Prev, 9, 381-6.
  3. Bhurgri Y, Hasan SH, Pervez S, et al (2002). Large-scale pathology-based cancer data: a reflection of population based cancer data. Pathol Oncol Res, 8, 62-7. https://doi.org/10.1007/BF03033704
  4. Bhurgri Y, Bhurgri A, Usman A, et al (2006). Epidemiology review of head and neck cancers in Karachi. Asian Pac J Cancer Prev, 7, 195-200.
  5. Binu VS, Chandrashekhar TS, Subba SH, et al (2007). Cancer pattern in western Nepal: a hospital based retrospective study. Asian Pac J Cancer Prev, 8, 183-6.
  6. Chaudhry S, Khan AA, Mirza KM, et al (2008). Estimating the burden of head and neck cancers in the public health sector of Pakistan. Asian Pac J Cancer Prev, 9, 529-32.
  7. Elango JK, Gangadharan P, Sumithra S, Kuriakose MA (2006). Trends of head and neck cancers in urban and rural India. Asian Pac J Cancer Prev, 7, 108-12.
  8. Gress DM (2002). Your cancer registry: more than just case counts. Oncol Issues, 17, 28-31.
  9. Jamal S, Moghal S, Mamoon N, et al (2006). The pattern of malignant tumours: tumour registry data analysis, AFIP, Rawalpindi, Pakistan (1992-2001). J Pak Med Assoc, 56, 359-62.
  10. Ologe FE, Adeniji KA, Segun-Busari S (2005). Clinicopathological study of head and neck cancers in Ilorin, Nigeria. Trop Doct, 35, 2-4. https://doi.org/10.1258/0049475053001949
  11. Thakur SKD, Sah SP, Lakhey M, Badhu BP (2003). Primary malignant tumours of eye and adnexa in eastern Nepal. Clin Experiment Ophthalmol, 31, 415-7. https://doi.org/10.1046/j.1442-9071.2003.00688.x
  12. Thapa N, Jha AK, Rijal JP, Shah A (2003). Study on head and neck tumours presented in ENT OPD of Nepal Medical College teaching Hospital. Nepal Med Coll J, 5, 79-81.
  13. Tobias JS (1994). Cancer of the head and neck. BMJ, 308, 961-6. https://doi.org/10.1136/bmj.308.6934.961
  14. Yeole BB (2007). Trends in incidence of head and neck cancers in India. Asian Pac J Cancer Prev, 8, 607-12.

Cited by

  1. Extraskeletal Ewing Sarcomas in Late Adolescence and Adults: A Study of 37 Patients vol.14, pp.5, 2013, https://doi.org/10.7314/APJCP.2013.14.5.2967
  2. Stage-Wise Presentation of Non-Metastatic Head and Neck Cancer: an Analysis of Patients from the Kumaon Hills of India vol.15, pp.12, 2014, https://doi.org/10.7314/APJCP.2014.15.12.4957
  3. Histopathological Patterns of Thyroid Disease in Al-Madinah Region of Saudi Arabia vol.15, pp.14, 2014, https://doi.org/10.7314/APJCP.2014.15.14.5565
  4. Head and neck extra nodal NHL (HNENL) - Treatment Outcome and Pattern of failure - A Single Institution Experience vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6267
  5. Epidemiological Study of Laryngeal Carcinoma in Western Nepal vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6541
  6. Treatment Outcome for Head and Neck Squamous Cell Carcinoma in a Developing Country: University Malaya Medical Centre, Malaysia from 2003-2010 vol.16, pp.7, 2015, https://doi.org/10.7314/APJCP.2015.16.7.2903
  7. Malignant Neoplasm Burden in Nepal - Data from the Seven Major Cancer Service Hospitals for 2012 vol.16, pp.18, 2016, https://doi.org/10.7314/APJCP.2015.16.18.8659
  8. The epidemiology of thyroid diseases in the Arab world: A systematic review vol.8, pp.2, 2016, https://doi.org/10.5897/JPHE2015.0713