Analysis and Stability Test of the Extracts from Dipsaci Radix, Leonuri Herba and Cyperi Rhizoma for Toxicity Study

속단, 익모초 및 향부자의 독성평가를 위한 성분분석 및 안정성 시험

  • Bae, Yoon-Ho (College of Pharmacy, Catholic University of Daegu) ;
  • Huh, Jung-Im (Korea Institute of Toxicology) ;
  • Kwack, Seung-Jun (College of Natural Science, Changwon National University) ;
  • Seok, Ji-Hyeon (Toxicological Evaluation and Research Department, Korea Food & Drug Administration) ;
  • Lee, Jong-Kwon (Toxicological Evaluation and Research Department, Korea Food & Drug Administration) ;
  • Kang, Tae-Suk (Toxicological Evaluation and Research Department, Korea Food & Drug Administration) ;
  • Woo, Mi-Hee (College of Pharmacy, Catholic University of Daegu) ;
  • Choi, Jae-Sue (Faculty of Food Science and Biotechnology, Pukyoung National University) ;
  • Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu)
  • 배윤호 (대구가톨릭대학교 약학대학) ;
  • 허정임 (안전성평가연구소) ;
  • 곽승준 (창원대학교 자연대학) ;
  • 석지현 (식품의약품안전청 독성평가연구부) ;
  • 이종권 (식품의약품안전청 독성평가연구부) ;
  • 강태석 (식품의약품안전청 독성평가연구부) ;
  • 우미희 (대구가톨릭대학교 약학대학) ;
  • 최재수 (부경대학교 식품생명공학부) ;
  • 민병선 (대구가톨릭대학교 약학대학)
  • Received : 2012.02.04
  • Accepted : 2012.02.27
  • Published : 2012.03.31

Abstract

A simple and reliable reverse phase HPLC method was developed to determine pharmacologically active marker compounds of Dipsaci Radix, Leonuri Herba and Cyperi Rhizoma. The stability test of water-extract of three natural medicines were examined for six months. However, no significant change in the content of the marker compounds of each extract observed during the time of investigation.

Keywords

References

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