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Impact of Advanced Maternal and Paternal Age on Perinatal Outcome

분만여성과 배우자의 출산연령이 산모와 신생아 합병증에 미치는 영향

  • Lee, Min-Kyung (College of Nursing Science, Kyung Hee University at Korea) ;
  • Shin, Hye-Sook (College of Nursing Science, Kyung Hee University at Korea) ;
  • Lee, Yun-Jung (College of Nursing Science, Kyung Hee University at Korea) ;
  • Kim, Ju-Hee (College of Nursing Science, Kyung Hee University at Korea)
  • 이민경 (경희대학교 간호과학대학) ;
  • 신혜숙 (경희대학교 간호과학대학) ;
  • 이윤정 (경희대학교 간호과학대학) ;
  • 김주희 (경희대학교 간호과학대학)
  • Received : 2011.11.27
  • Accepted : 2012.03.09
  • Published : 2012.04.30

Abstract

Purpose: This study aimed to analyze the impact of advanced maternal and paternal age on perinatal outcome in Korea. Methods: We conducted a retrospective study involving 1,622 Korean women who delivered at M Woman Hospital from January to December 2010 and their spouses were included. We obtained obstetrics database which included demographic characteristics, medical and obstetrics history, course of the current pregnancy and advised perinatal outcome. Multivariable logistic regression was used to adjust for potential confounding variables. Results: Women giving birth age 35 or older were statistically significant in paternal age, gravidity, spontaneous abortion experience, method of conception, method of delivery, and multiple gestation compared to women aged <34 years. After adjusting for the confounding effects of maternal characteristics, women aged 35 or older were at increased risk for cesarean section delivery (adjusted OR 1.6, 95% CI 1.22-2.13) and preterm birth (adjusted OR 2.2, 95% CI 1.03-4.63). Conclusion: In this population of Korean women, advance maternal and paternal age is independently associated with specific adverse perinatal outcome, especially preterm birth and cesarean section delivery.

Keywords

References

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