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A Case of Pituitary Metastasis from Breast Cancer That Presented as Left Visual Disturbance

  • Kim, Young-Ha (Department of Otolaryngology-HNS, College of Medicine, The Catholic University of Korea) ;
  • Lee, Beom-Jun (Department of Otolaryngology-HNS, College of Medicine, The Catholic University of Korea) ;
  • Lee, Kyung-Jin (Department of Neurosurgery, College of Medicine, The Catholic University of Korea) ;
  • Cho, Jin-Hee (Department of Otolaryngology-HNS, College of Medicine, The Catholic University of Korea)
  • Received : 2011.06.28
  • Accepted : 2012.02.24
  • Published : 2012.02.28

Abstract

Tumors that metastasize to the pituitary gland are unusual, and are typically seen in elderly patients with diffuse malignant disease. The most common metastases to the pituitary are from primary breast and lung cancers. We report a 65-year-old woman with pituitary metastasis from breast cancer who presented with recent-onset left progressive deterioration of visual acuity and visual field. The clinical diagnosis was made after brain and sellar magnetic resonance imaging showed a large sellar mass compressing the optic chiasm and invading the pituitary stalk. An otorhinolaryngology and neurosurgery team removed the tumor via a transsphenoidal approach, and this procedure obtained symptomatic relief. Postoperatively, metastasis from breast invasive ductal adenocarcinoma was confirmed histologically. We report this unusual case with a review of the relevant literature.

Keywords

References

  1. Chiang MF, Brock M, Patt S : Pituitary metastases. Neurochirurgia (Stuttg) 33 : 127-131, 1990
  2. Fassett DR, Couldwell WT : Metastases to the pituitary gland. Neurosurg Focus 16 : E8, 2004 https://doi.org/10.3171/foc.2004.16.2.1
  3. Heshmati HM, Scheithauer BW, Young WF : Metastases to the pituitary gland. Endocrinologist 12 : 45-49, 2002 https://doi.org/10.1097/00019616-200201000-00010
  4. Houck WA, Olson KB, Horton J : Clinical features of tumor metastasis to the pituitary. Cancer 26 : 656-659, 1970 https://doi.org/10.1002/1097-0142(197009)26:3<656::AID-CNCR2820260325>3.0.CO;2-M
  5. Komninos J, Vlassopoulou V, Protopapa D, Korfias S, Kontogeorgos G, Sakas DE, et al. : Tumors metastatic to the pituitary gland : case report and literature review. J Clin Endocrinol Metab 89 : 574-580, 2004 https://doi.org/10.1210/jc.2003-030395
  6. Kurkjian C, Armor JF, Kamble R, Ozer H, Kharfan-Dabaja MA : Symptomatic metastases to the pituitary infundibulum resulting from primary breast cancer. Int J Clin Oncol 10 : 191-194, 2005 https://doi.org/10.1007/s10147-004-0458-5
  7. Kwak JW, Jie BS, Hong SH, Kim JH, Lee SH, Jo JH, et al. : A case of pituitary metastasis of breast cancer presenting as diabetes insipidus and panhypopituitarism. J Korean Endocr Soc 22 : 125-129, 2007 https://doi.org/10.3803/jkes.2007.22.2.125
  8. Morita A, Meyer FB, Laws ER Jr : Symptomatic pituitary metastases. J Neurosurg 89 : 69-73, 1998 https://doi.org/10.3171/jns.1998.89.1.0069
  9. Moses AM, Clayton B, Hochhauser L : Use of T1-weighted MR imaging to differentiate between primary polydipsia and central diabetes insipidus. AJNR Am J Neuroradiol 13 : 1273-1277, 1992
  10. Ruelle A, Palladino M, Andrioli GC : Pituitary metastases as presenting lesions of malignancy. J Neurosurg Sci 36 : 51-54, 1992
  11. Shin ET, Lee EJ, Kim KR, Lee KM, Bae HD, Lee KS, et al. : A case of pituitary metastasis from periampullary carcinoma. J Korean Soc Endocrinol 8 : 88-93, 1993
  12. Sioutos P, Yen V, Arbit E : Pituitary gland metastases. Ann Surg Oncol 3 : 94-99, 1996 https://doi.org/10.1007/BF02409058
  13. Teears RJ, Silverman EM : Clinicopathologic review of 88 cases of carcinoma metastatic to the putuitary gland. Cancer 36 : 216-220, 1975 https://doi.org/10.1002/1097-0142(197507)36:1<216::AID-CNCR2820360123>3.0.CO;2-E
  14. Weil RJ : Pituitary metastasis. Arch Neurol 59 : 1962-1963, 2002 https://doi.org/10.1001/archneur.59.12.1962
  15. Yi HJ, Kim CH, Bak KH, Kim JM, Ko Y, Oh SJ : Metastatic tumors in the sellar and parasellar regions: clinical review of four cases. J Korean Med Sci 15 : 363-367, 2000 https://doi.org/10.3346/jkms.2000.15.3.363

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