Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
권호 표지
DOI QR코드

DOI QR Code

Changes in Sensitization Rate to Weed Allergens in Children with Increased Weeds Pollen Counts in Seoul Metropolitan Area

  • Kim, Joo-Hwa (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Oh, Jae-Won (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Lee, Ha-Baik (Department of Pediatrics, Hanyang University College of Medicine) ;
  • Kim, Seong-Won (Department of Pediatrics, Busan St. Maria Hospital) ;
  • Kang, Im-Joo (Department of Pediatrics, Daegu Fatima Hospital) ;
  • Kook, Myung-Hee (Department of Pediatrics, Gwangju Veteran’s Hospital) ;
  • Kim, Bong-Seong (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Kang-Seo (Department of Pediatrics, Jeonju Jesus Hospital) ;
  • Baek, Hey-Sung (Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Kyu-Rang (Applied Meteorology Research Laboratory, National Institute of Meteorological Research) ;
  • Choi, Young-Jean (Applied Meteorology Research Laboratory, National Institute of Meteorological Research)
  • Published : 2012.04.02
⟨ Previous Next ⟩

Abstract

The prevalence of allergic diseases in children has increased for several decades. We evaluated the correlation between pollen count of weeds and their sensitization rate in Seoul, 1997-2009. Airborne particles carrying allergens were collected daily from 3 stations around Seoul. Skin prick tests to pollen were performed on children with allergic diseases. Ragweed pollen gradually increased between 1999 and 2005, decreased after 2005 and plateaued until 2009 (peak counts, 67 in 2003, 145 in 2005 and 83 grains/$m^{3}$/day in 2007). Japanese hop pollen increased between 2002 and 2009 (peak counts, 212 in 2006 and 492 grains/$m^{3}$/day in 2009). Sensitization rates to weed pollen, especially ragweed and Japanese hop in children with allergic diseases, increased annually (ragweed, 2.2% in 2000 and 2.8% in 2002; Japanese hop, 1.4% in 2000 and 1.9% in 2002). The age for sensitization to pollen gradually became younger since 2000 (4 to 6 yr of age, 3.5% in 1997 and 6.2% in 2009; 7 to 9 yr of age, 4.2% in 1997 and 6.4% in 2009). In conclusion, sensitization rates for weed pollens increase in Korean children given increasing pollen counts of ragweed and Japanese hop.

Keywords

References

  1. Asher MI, Montefort S, Bjorksten B, Lai CK, Strachan DP, Weiland SK, Williams H; ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006; 368: 733-43. https://doi.org/10.1016/S0140-6736(06)69283-0
  2. Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med 2006; 355: 2226-35. https://doi.org/10.1056/NEJMra054308
  3. Hong SJ, Ahn KM, Lee SY, Kim KE. The prevalences of asthma and allergic diseases in Korean children. Korean J Pediatr 2008; 51: 343-50. https://doi.org/10.3345/kjp.2008.51.4.343
  4. Jee HM, Kim KW, Kim CS, Sohn MH, Shin DC, Kim KE. Prevalence of asthma, rhinitis and eczema in Korean children using the International Study Of Asthma and Allergies In Childhood (ISAAC) questionnaires. Pediatr Allergy Respir Dis 2009; 19: 165-72.
  5. Beggs PJ. Impacts of climate change on aeroallergens: past and future. Clin Exp Allergy 2004; 34: 1507-13. https://doi.org/10.1111/j.1365-2222.2004.02061.x
  6. Bernard SM, Samet JM, Grambsch A, Ebi KL, Romieu I. The potential impacts of climate variability and change on air pollution-related health effects in the United States. Environ Health Perspect 2001; 109: 199-209.
  7. D'Amato G, Liccardi G, D'Amato M, Holgate S. Environmental risk factors and allergic bronchial asthma. Clin Exp Allergy 2005; 35: 1113-24. https://doi.org/10.1111/j.1365-2222.2005.02328.x
  8. Frenguelli G. Interactions between climatic changes and allergenic plants. Monaldi Arch Chest Dis 2002; 57: 141-3.
  9. Namork E, Johansen BV, Lovik M. Detection of allergens adsorbed to ambient air particles collected in four European cities. Toxicol Lett 2006; 165: 71-8. https://doi.org/10.1016/j.toxlet.2006.01.016
  10. Oh JW, Lee HB, Kang IJ, Kim SW, Park KS, Kook MH, Kim BS, Baek HS, Kim JH, Kim JK, Lee DJ, Kim KR, Choi YJ. The revised edition of Korean calendar for allergenic pollens. Allergy Asthma Immunol Res 2012; 4: 5-11. https://doi.org/10.4168/aair.2012.4.1.5
  11. Knox RB, Suphioglu C, Taylor P, Desai R, Watson HC, Peng JL, Bursill LA. Major grass pollen allergen Lol p 1 binds to diesel exhaust particles: implications for asthma and air pollution. Clin Exp Allergy 1997; 27: 246-51. https://doi.org/10.1111/j.1365-2222.1997.tb00702.x
  12. D'Amato G, Cecchi L. Effects of climate change on environmental factors in respiratory allergic diseases. Clin Exp Allergy 2008; 38: 1264-74. https://doi.org/10.1111/j.1365-2222.2008.03033.x
  13. Ayres JG, Forsberg B, Annesi-Maesano I, Dey R, Ebi KL, Helms PJ, Medina- Ramon M, Windt M, Forastiere F; Environment and Health Committee of the European Respiratory Society. Climate change and respiratory disease: European Respiratory Society position statement. Eur Respir J 2009; 34: 295-302. https://doi.org/10.1183/09031936.00003409
  14. Park HS, Nahm DH, Suh CH, Lee SM, Choi SY, Jung KS, Lee SY, Park K. Evidence of Hop Japanese pollinosis in Korea: IgE sensitization and identification of allergenic components. J Allergy Clin Immunol 1997; 100: 475-9. https://doi.org/10.1016/S0091-6749(97)70138-6
  15. Hirschwehr R, Heppner C, Spitzauer S, Sperr WR, Valent P, Berger U, Horak F, Jager S, Kraft D, Valenta R. Identification of common allergenic structures in mugwort and ragweed pollen. J Allergy Clin Immunol 1998; 101: 196-206. https://doi.org/10.1016/S0091-6749(98)70384-7
  16. Ziska LH, Gebhard DE, Frenz DA, Faulkner S, Singer BD, Straka JG. Cities as harbingers of climate change: common ragweed, urbanization, and public health. J Allergy Clin Immunol 2003; 111: 290-5. https://doi.org/10.1067/mai.2003.53
  17. Fitter AH, Fitter RS. Rapid changes in flowering time in British plants. Science 2002; 296: 1689-91. https://doi.org/10.1126/science.1071617
  18. Singer BD, Ziska LH, Frenz DA, Gebhard DE, Straka JG. Increasing Amb a 1 content in common ragweed (Ambrosia artemisiifolia) pollen as a function of rising atmospheric $CO_{2}$ concentration. Funct Plant Biol 2005; 32: 667-70. https://doi.org/10.1071/FP05039
  19. Environment RoKMo. List of environmentally harmful animals and plants in Korea. ME Publishing (Korean) 2009; ISBN 11-1480000-001000-01: 95-102.
  20. Oh JW, Lee HR, Kim JS, Lee KI, Kang YJ, Kim SW, Kook MH, Kang HY, Kim JS, Lee MH, Lee HB, Kim KE, Pyun BY, Lee SI, Han MJ. Aerobiological study of pollen and mold in the 10 states of Korea. Pediatr Allergy Respir Dis 2000; 10: 22-33.
  21. Ziska LH, Caulfield FA. Rising $CO_{2}$ and pollen production of common ragweed (Ambrosia artemisiifolia L.), a known allergy-inducing species: implications for public health. Aust J Plant Physiol 2000; 27: 893-8.
  22. Ackermann-Liebrich U, Schindler C, Frei P, Probst-Hensch NM, Imboden M, Gemperli A, Rochat T, Schmid-Grendemeier P, Bircher AJ. Sensitisation to Ambrosia in Switzerland: a public health threat on the wait. Swiss Med Wkly 2009; 139: 70-5.
  23. Frenz DA. Interpreting atmospheric pollen counts for use in clinical allergy: allergic symptomology. Ann Allergy Asthma Immunol 2001; 86: 150-7. https://doi.org/10.1016/S1081-1206(10)62683-X
  24. Ehara K. Comparative morphological studies of the hop (Humulus lupulus L.) and the Japanese hop (H. japonicus Sieb. et Zucc.) Part I. J Fac Agric Kyushu Univ 1955; 10: 209-32.
  25. Cronk QC, Fuller JL. Plant invaders: the threat to natural ecosystems. London: Chapman & Hall, 1995, p241.
  26. Wittenberg R, Cock MJW. Invasive alien species. How to address one of the greatest threats to biodiversity: a toolkit of best prevention and management practices. Oxon: CAB International, 2001.

Cited by

  1. 알레르기 꽃가루 위험도 예보모델의 개발과 검증 vol.14, pp.4, 2012, https://doi.org/10.5532/kjafm.2012.14.4.265
  2. Sensitization rates to inhalant allergens in children and adolescents of Incheon and Asan area and the relationship between polysensitization and prevalence of allergic diseases vol.1, pp.1, 2012, https://doi.org/10.4168/aard.2013.1.1.41
  3. Paradoxical Increase of IgE Binding Components during Allergen-Specific Immunotherapy in Pollinosis Patients vol.29, pp.7, 2014, https://doi.org/10.3346/jkms.2014.29.7.1025
  4. Identification of IgE binding components of two major weed pollens, ragweed and mugwort vol.2, pp.5, 2012, https://doi.org/10.4168/aard.2014.2.5.337
  5. The correlation between allergy sensitization rate in pediatric and aerobiological study for airborne pollen in Busan for 15 years vol.2, pp.1, 2012, https://doi.org/10.4168/aard.2014.2.1.38
  6. Evaluation of the association of vegetation of allergenic plants and pollinosis with meteorological changes vol.2, pp.1, 2012, https://doi.org/10.4168/aard.2014.2.1.48
  7. Association Between the Sensitization Rate for Inhalant Allergens in Patients with Respiratory Allergies and the Pollen Concentration in Ulsan, Korea vol.86, pp.4, 2012, https://doi.org/10.3904/kjm.2014.86.4.453
  8. Changes of aeroallergen sensitization in children with asthma or allergic rhinitis from a tertiary referral hospital in Seoul over 10 years vol.2, pp.2, 2012, https://doi.org/10.4168/aard.2014.2.2.97
  9. Ragweed-induced allergic rhinoconjunctivitis: current and emerging treatment options vol.8, pp.None, 2012, https://doi.org/10.2147/jaa.s47789
  10. Cross-allergenicity between dandelion and major weed pollens vol.3, pp.5, 2012, https://doi.org/10.4168/aard.2015.3.5.358
  11. Evaluation of the association between pollen count and the outbreak of allergic disease vol.4, pp.6, 2012, https://doi.org/10.4168/aard.2016.4.6.415
  12. A Six-Year Study on the Changes in Airborne Pollen Counts and Skin Positivity Rates in Korea: 2008–2013 vol.57, pp.3, 2012, https://doi.org/10.3349/ymj.2016.57.3.714
  13. Particularities of allergy in the Tropics vol.9, pp.None, 2012, https://doi.org/10.1186/s40413-016-0110-7
  14. Regional Difference of Causative Pollen in Children with Allergic Rhinitis vol.32, pp.6, 2017, https://doi.org/10.3346/jkms.2017.32.6.926
  15. Clinical diagnostic guidelines for allergic rhinitis: diagnosis vol.60, pp.1, 2012, https://doi.org/10.5124/jkma.2017.60.1.81
  16. Characteristics of airborne pollen in Incheon and Seoul (2015–2016) vol.7, pp.3, 2012, https://doi.org/10.5415/apallergy.2017.7.3.138
  17. Evaluation of the allergenic relationship betweenHumulus japonicusandHumulus lupuluspollen allergens vol.5, pp.4, 2012, https://doi.org/10.4168/aard.2017.5.4.217
  18. Distinct epitope structures of defensin‐like proteins linked to proline‐rich regions give rise to differences in their allergenic activity vol.73, pp.2, 2012, https://doi.org/10.1111/all.13298
  19. Chamber and Field Studies demonstrate Differential Amb a 1 Contents in Common Ragweed Depending on CO 2 Levels vol.10, pp.3, 2012, https://doi.org/10.4168/aair.2018.10.3.278
  20. Allergic sensitization and its association with air pollution in childhood allergic rhinitis vol.6, pp.4, 2012, https://doi.org/10.4168/aard.2018.6.4.189
  21. Etiology and clinical feature of oral allergy syndrome in children vol.6, pp.4, 2012, https://doi.org/10.4168/aard.2018.6.4.219
  22. The impact of climate change on pollen allergy in Korea vol.6, pp.suppl1, 2018, https://doi.org/10.4168/aard.2018.6.s1.s31
  23. Changes of aeroallergen sensitization in childhood vol.7, pp.4, 2019, https://doi.org/10.4168/aard.2019.7.4.171
  24. Recent changing pattern of aeroallergen sensitization in children with allergic diseases: A single center study vol.7, pp.4, 2019, https://doi.org/10.4168/aard.2019.7.4.186
  25. Short-term effects of multiple outdoor environmental factors on risk of asthma exacerbations: Age-stratified time-series analysis vol.144, pp.6, 2012, https://doi.org/10.1016/j.jaci.2019.08.037
  26. Trends of Sensitization to Inhalant Allergens in Korean Children Over the Last 10 Years vol.61, pp.9, 2020, https://doi.org/10.3349/ymj.2020.61.9.797
  27. Pollen-food allergy syndrome in children vol.63, pp.12, 2012, https://doi.org/10.3345/cep.2019.00780
  28. Increased sensitization rates to tree pollens in allergic children and adolescents and a change in the pollen season in the metropolitan area of Seoul, Korea vol.32, pp.5, 2012, https://doi.org/10.1111/pai.13472