Journal of Acupuncture & Meridian Studies

Medical Association of pharmacopuncture Institute (사단법인약침학회)
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Sweet Bee Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy

  • Yoon, Jeungwon (East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University) ;
  • Jeon, Ju-Hyun (East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University) ;
  • Lee, Yeon-Weol (East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University) ;
  • Cho, Chong-Kwan (East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University) ;
  • Kwon, Ki-Rok (Korean Pharmacopuncture Institute) ;
  • Shin, Ji-Eun (Department of Statistics, Chungnam National University) ;
  • Sagar, Stephen (Juravinski Cancer Center, McMaster University) ;
  • Wong, Raimond (Juravinski Cancer Center, McMaster University) ;
  • Yoo, Hwa-Seung (East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University)
  • Published : 2012.08.31
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Abstract

Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is sensory and motor nerve damage to the peripheral nervous system caused by chemotherapeutic agents. It often causes pain and other varying degrees of neuropathic symptoms accompanied by functional limitations and reduced quality of life. Currently, there is no standard treatment protocol for the treatment of CIPN. Objective: In need of more research to develop new therapeutic options focusing on their safety, efficacy, and long-term sustained clinical effects, a pilot study of sweet bee venom pharmacopuncture (SBVP) for CIPN was conducted to build up preliminary efficacy data in the process of preparing for a future larger scale randomized controlled SBVP trial for CIPN. Methods: We conducted a prospective case series by analyzing the clinical observations made of CIPN patients treated with SBVP. A total of 11 eligible consecutive CIPN patients who visited East-West Cancer Center from June 1, 2010, to February 28, 2011, were treated with total of six SBVP treatments given within the 3-week period. The outcomes were measured using World Health Organization Common Toxicity Criteria for Peripheral neuropathy (WHO grading system), Patient Neurotoxicity Questionnaire (PNQ), Visual Analogue System (VAS), and Health-Related Quality of Life (HRQOL) collected at the baseline, post-second, fourth, and the final treatment. Patients were followed 3 weeks into no intervention to determine the sustained effects of pharmacopuncture.

Keywords

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