The Associated Factors with Whole Saliva Flow Rate and Xerostomia

전타액분비율과 구강건조증의 관련요인 분석

  • Park, Eun-Seon (Graduate School of Public Health, Gachon University) ;
  • Choi, Jun-Seon (Dept. of Dental Hygiene, College of Medical Science, Gachon University)
  • Published : 2012.04.30

Abstract

The aim of this study was to analyze the factors related to whole saliva flow and the xerostomia for the ground use of the materials in developing oral health improvement program and life quality improvement program. So, this study performed a questionnaire survey, targeting at 160 adults, older than 40 years, living in Gyeonggi and Incheon provinces from January to February 2011 and measured unstimulated salivary flow rate and stimulated salivary flow rate. The results are as followings. The group of participants who took gums and candies to relieve oral dryness had low stimulated whole saliva flow. The group of participants who graduated from middle schools, who separated by death, who were not healthy with menopause, and who recognized periodontal disease symptoms and tongue burning sensation recognized more symptoms of dry mouth than others. In addition, the group of participants who were not satisfied with life so much, who couldn't feel the meaning of life, and who recognized negative feelings frequently recognized symptoms of dry mouth more. Women, the group of participants who graduated from middle schools, who suffered from depressive symptoms, and who recognized halitosis had low unstimulated whole saliva flow. The group of participants who graduated from middle schools, who were not satisfied with life so much, who couldn't feel the meaning of life, and who were not satisfied with themselves had low stimulated saliva flow.

본 연구는 구강건조증과 전타액분비율과의 관련요인을 분석함으로써 건강인식도를 높이고, 삶의 질 향상 프로그램을 개발하는데 기초자료로 활용하고자 실시하였다. 2011년 1월 14일부터 2월 22일까지 경기 인천 지역에 거주하는 만 40세 이상의 성인 160명을 대상으로 설문조사와 비자극성, 자극성 전타액분비량을 측정하여 다음과 같은 결론을 얻었다. 1. 구강건조증 인식도와 전타액분비율과의 관련성을 분석한 결과 '구강건조의 완화를 위해 껌 사탕을 섭취'하는 집단에서 자극성 전타액분비율이 낮았다. 2. 중학교 졸업자와 사별(미혼) 집단에서 구강건조증을 더 많이 인식하고 있었다. 또한 중학교 졸업자는 고등학교 졸업자보다 비자극성 전타액분비율과 자극성 타액분비율이 더 낮았고, 여성은 남성보다 비자극성 전타액분비율이 낮았다. 3. 건강상태가 좋지 않으며 폐경 상태이고, 우울증 증상이 많으며, 치주질환 증상과 혀 작열감 등을 인식한 집단에서 구강건조증을 더 많이 인식하고 있었다. 또한 우울증의 증상이 많고 구취를 인식한 집단에서 비자극성 전타액분비율이 낮았다. 4. 삶의 만족도가 낮고 삶이 무의미하며 부정적 기분을 자주 인지하고, 구강건강과 관련된 삶의 질이 낮은 집단에서 구강건조증을 더 많이 인식하고 있었다. 또한 삶의 만족도가 낮고 삶이 무의미하며, 자신에 대한 만족도가 낮은 집단에서 자극성 전타액분비율이 더 낮았다. 이상의 결과로 볼 때, 전신건강과 구강건강인식도 및 삶의 질의 향상을 위하여 구강건조증과 타액분비의 저하는 조기에 예방하여야 하며, 삶의 질 향상 프로그램에 반드시 포함하여야 할 것으로 사료되었다.

Keywords

References

  1. Fox PC et al.: Xerostomia: evaluation of a symptom of a symptom with increasing significance. J Am Dent Assoc 110(4): 519-525, 1985.
  2. Orellana MF et al.: Prevalence of xerostomia in population-based samples; a systematic review. J Public Health Dent 66(2): 152-158, 2006. https://doi.org/10.1111/j.1752-7325.2006.tb02572.x
  3. Nederfors T et al.: Prevalence of perceived symptoms of dry mouth in an adult Swedish population - relation to age, sex and pharmacotherapy. Community Dent Oral Epidemiol 25(3): 211-216, 1997. https://doi.org/10.1111/j.1600-0528.1997.tb00928.x
  4. Dawes C: Physiological factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man. J Dent Res 66(spec): 648-653, 1987.
  5. Fox PC, Busch KA, Baum BJ: Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc 115(4): 501-584, 1987.
  6. Sreebny LM, Valdini A: Xerostomia. part I: relationship to other oral symptoms and salivary gland hypofunction. Oral Surg Oral Med Oral Pathol 66(4): 451-458, 1988. https://doi.org/10.1016/0030-4220(88)90268-X
  7. Axelsson PJ: Diagnosis and risk prediction of caries. 2th ed. Quintessence, Stockholm, pp. 94, 2000.
  8. Thomson WM et al.: Is medication a risk factor for dental caries among older people?. Community Dent Oral Epidemiol 30(3): 224-332, 2002. https://doi.org/10.1034/j.1600-0528.2002.300309.x
  9. Sreebny LM, Schwartz SS: A reference guide to drugs and dry mouth--2nd edition. Gerodontology 14(1): 33-47, 1997. https://doi.org/10.1111/j.1741-2358.1997.00033.x
  10. Screebny LM, Schwartz SS: A reference guide to drugs and dry mouth. Gerodontology 5(2): 75-99, 1986. https://doi.org/10.1111/j.1741-2358.1986.tb00055.x
  11. Bergdahl M: Salivary flow and oral complaints in adult dental patients. Community Dent Oral Epidemiol 28(1): 59-66, 2000. https://doi.org/10.1034/j.1600-0528.2000.280108.x
  12. Billings RJ. Proskin HM, Moss ME: Xerostomia and associated factors in a community-dwelling adult population. Community Dent Oral Epidemiol 24(5): 312-316, 1996. https://doi.org/10.1111/j.1600-0528.1996.tb00868.x
  13. Cassolato SF, Turnbull RS: Xerostomia: clinical aspects and treatment. Gerodontology 20(2): 64-77, 2003. https://doi.org/10.1111/j.1741-2358.2003.00064.x
  14. Thomson WM et al.: The impact of xerostomia on oral-health-related quality of life among younger adults. Health Qual Life Outcome 8(4): 86, 2006.
  15. Beck AT, Steer RA, Garbin MG: Psychometric properties of the Beck Depression Inventory:twenty-five years of evaluation. Clin Psychol Rev 8(1): 77-100, 1988. https://doi.org/10.1016/0272-7358(88)90050-5
  16. Ng SKS, Leung WK: Oral health-related quality of life and periodontal status. Community Dent Oral Epidemiol 34(2): 114-122, 2006. https://doi.org/10.1111/j.1600-0528.2006.00267.x
  17. Busato IMS, Brancher JA, Machado MAN: Impact of xerostomia on the quality of life of adolescents with type 1 diabetes mellitus. Oral Surg Oral Med Oral Pathol Oral Radio Endod 108(3): 376-382, 2009. https://doi.org/10.1016/j.tripleo.2009.05.005
  18. Slade GD: Derivation and validation of a short form oral health impact profile. Community Dent Oral Epidemiol 25(4): 284-290, 1997. https://doi.org/10.1111/j.1600-0528.1997.tb00941.x
  19. World Health Organization: Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol Med 28(3): 551-558, 1998. https://doi.org/10.1017/S0033291798006667
  20. Thomson WM, Williams SM: Further testing of the xerostomia inventory. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89(1): 46-50, 2000. https://doi.org/10.1016/S1079-2104(00)80013-X
  21. Narhi TO: Prevalence of subjective feeling of dry mouth in early. J Dent Res 73: 20-25, 1994. https://doi.org/10.1177/00220345940730010301
  22. Thomson WM et al.: The occurrence of xerostomia and salivary gland hypofunction in a population - based sample of older South Australians. Spec Care Dentist 19(1): 20-23, 1999. https://doi.org/10.1111/j.1754-4505.1999.tb01363.x
  23. 이정윤, 이영옥, 고흥섭: 구강건조증 증상 평가를 위한 설문지의 신뢰도에 관한 연구. 대한구강내과학회지 30(4): 383-389, 2005.
  24. Flink H et al.: Prevalence of hyposalivation in relation to general health, body mass index and remaining teeth in different age groups of adults. Community Dent Oral Epidemiol 36(6): 523-531, 2008. https://doi.org/10.1111/j.1600-0528.2008.00432.x
  25. 이지혜: 한국노인의 구강건조증의 관련요소 및 구강건조증이 구강건강과 관련된 삶의 질에 미치는 영향[석사학위논문]. 서울대학교 대학원, 서울, 2006.
  26. Ben-Aryeh H et al.: Whole saliva secreted by old and young healthy subjects. J Dent Res 63(9): 1147-1148, 1984. https://doi.org/10.1177/00220345840630091001
  27. Ghezzi EM, Ship JA: Aging an secretory reserve capacity of major salivary glands. J Dent Res 82(10): 844-848, 2003. https://doi.org/10.1177/154405910308201016
  28. Anttila SS, Knuuttila ML, Sakki TK: Depressive symptoms as an underlying factor of the sensation of dry mouth. Psychosom Med 60(2): 215-218, 1998.
  29. Percival RS, Challacombe SJ, Marsh PD: Flow rates of resting whole and stimulated parotid saliva in relation to age and gender. J Dent Res 73(8): 1416-1420, 1994.
  30. Sreebny LM, Valdini A, Yu A: Xerostomia. part II: relationship to nonoral symtoms, drugs, and diseases. Oral Surg Oral Med Oral Pathol 68(4): 419-427, 1989. https://doi.org/10.1016/0030-4220(89)90140-0
  31. Thomson WM, Chalmers JM, Spencer AJ: A longitudinal study of medication exposure and xerostomia among older people. Gerodontology 23(4): 205-213, 2006. https://doi.org/10.1111/j.1741-2358.2006.00135.x
  32. Smidt D et al.: Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people. Community Dent Oral Epidemiol 38(5): 422-435, 2010. https://doi.org/10.1111/j.1600-0528.2010.00554.x
  33. Leal SC et al.: Medication in elderly people: its influence on salivary pattern, signs and symptoms of dry mouth. Gerodontology 27(2): 129-133, 2010. https://doi.org/10.1111/j.1741-2358.2009.00293.x
  34. 지윤정 등: 구취발생과 구강환경의 연관성에 관한 연구. 치위생과학회지 10(2): 101-107, 2010.
  35. Sreebny LM, Valdini A: Xerostomia: a neglected symptom. Arch Intern Med 147(7): 1333-1337, 1987. https://doi.org/10.1001/archinte.1987.00370070145022
  36. 장경애, 황인철: 노인의 구강기능 향상에 미치는 구강운동의 효과. 치위생과학회지 11(3): 257-263, 2011.
  37. Odusola F: Chewing gum as an aid in treatment of hyposalivation. NY State Dent J 57(4): 28-31, 1991.
  38. Daniels TE, Wu AJ: Xerostomia - clinical evaluation and treatment in general practice. J Can Dent Assoc 28(12): 933-941, 2000.