Journal of Breast Cancer

Korean Breast Cancer Society (한국유방암학회)
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Dose-Volume Analysis of Lung and Heart according to Respiration in Breast Cancer Patients Treated with Breast Conserving Surgery

  • Shim, Jae-Goo (Department of Radiological Science, Hanseo University) ;
  • Kim, Jeong-Koo (Department of Radiological Science, Hanseo University) ;
  • Park, Won (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Seo, Jeong-Min (Department of Radiological Technology, Daewon University College) ;
  • Hong, Chae-Sun (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Song, Ki-Won (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Cheong-Hwan (Department of Radiological Science, Hanseo University) ;
  • Jung, Hong-Ryang (Department of Radiological Science, Hanseo University) ;
  • Kim, Chan-Hyeong (Department of Nuclear Engineering, Hanyang University)
  • Published : 2012.03.30
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Abstract

Purpose: Adjuvant radiotherapy of breast cancer using a photon tangential field incurs a risk of late heart and lung toxicity. The use of free breathing (FB), expiration breath hold (EBH), and deep inspiration breath hold (DIBH) during tangential breast radiotherapy as a means of reducing irradiated lung and heart volume was evaluated. Methods: In 10 women with left-sided breast cancer (mean age, 44 years) post-operative computed tomography (CT) scanning was done under different respiratory conditions using FB, EBH, and DIBH in 3 CT scans. For each scan, an optimized radiotherapy plan was designed with 6 MV photon tangential fields encompassing the clinical target volume after breast-conserving surgery. Results: The results of dose-volume histograms were compared using three breathing pattern techniques for the irradiated volume and dose to the heart. A significant reduction dose to the irradiated heart volume for the DIBH breathing technique was compared to FB and EBH breathing techniques (p<0.05). Conclusion: This study demonstrated that the irradiated heart volume can be significantly reduced in patients with left-sided breast cancer using the DIBH breathing technique for tangential radiotherapy.

Keywords

References

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