Fabrication of PCL scaffold using autoadhesion phenomenon

Autoadhesion 현상을 이용한 PCL 세포 지지체 제작

  • 이세환 (원광대학교 기계공학과(원)) ;
  • 최기평 (원광대학교 기계공학과(원)) ;
  • 안상현 (원광대학교 기계공학과(원)) ;
  • 우창희 (원광대학교 기계공학과(원)) ;
  • 조영삼 (원광대학교 기계자동차공학부)
  • Published : 2012.04.30

Abstract

In this article, we proposed a novel technique to fabricate cell culturing scaffold, that is, the hollow cylinder grain assembly technique. This technique uses hollow cylindrical particles with sub-mm thickness. Firstly, we fabricate PCL (polycaprolactone) hollow cylinder with sub-mm thickness using lab-made stainless steel mold. After that, we put the above-mentioned fabricated particles into a metal mold of which temperature could be controlled with hot plate and heat insulation system. PCL particles in the metal mold could be assembled together without severe collapsing under adequate temperature and time. Consequently, we could fabricate scaffold or foam structure with interconnected porosity and observed surface of cross section of fabricated scaffold by SEM.

Keywords

References

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