The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
권호 표지
DOI QR코드

DOI QR Code

The Compositional Differences of Sipjeondaebo-tang(Siquandabu-tang) Decoctions Extracted by Different Extraction Method and Extraction Time

전탕 방법 및 전탕 시간에 따른 십전대보탕 전탕액 비교 연구

  • Kim, Jung-Hoon (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine) ;
  • Seo, Chang-Seob (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine) ;
  • Jeon, Woo-Young (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine) ;
  • Shin, Hyeun-Kyoo (Basic Herbal Medicine Research Group, Korea Institute of Oriental Medicine)
  • 김정훈 (한국한의학연구원 한약기초연구그룹) ;
  • 서창섭 (한국한의학연구원 한약기초연구그룹) ;
  • 전우영 (한국한의학연구원 한약기초연구그룹) ;
  • 신현규 (한국한의학연구원 한약기초연구그룹)
  • Received : 2012.04.26
  • Accepted : 2012.05.15
  • Published : 2012.05.25
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: This study was performed to compare the differences between decoctions extracted by different extraction method and extraction time. Methods: Decoctions were prepared with pressurized or non-pressurized extraction for 60, 120 and 180min. The yield of extract, total soluble solid content, hydrogen ion concentration(pH) and the content of reference compound in Sipjeondaebo-tang (Siquandabu-tang) were investigated. Results: While yields and the total soluble solid of decoction were higher in pressurized method proportional to extraction time, pH values were lower in pressurized method and showed decreasing values with increasing extraction time. Albilflorin, ferulic acid, nodakenin, coumarin, cinnamaldehyde and glycyrrhizin were contained in decoctions by pressurized extraction method more than non-pressurized method whereas the content of coumarin was higher in decoctions by non-pressurized extraction method. In addition, coumarin was extracted increasingly with extraction time in decoctions by pressurized method, however, nine compounds except cinnamaldehyde showed the tendency of increasing proportional to extraction time. Conclusions: The results show that extraction methods including pressurized or non-pressurized extraction, and extraction time could affect the physicochemical characteristic or composition of Sipjeondaebo-tang(Siquandabu-tang) decoction.

Keywords

References

  1. 杜中惠. 煎煮时间对四物汤某些成分含量的影响. 中国药业. 2001;10(4):31.
  2. Wu HW, et al. Study of effective ingredient in Huanglianjiedu decoction under different decocting conditions. Chinese Journal of Information on TCM. 2010;17(2):42-4.
  3. 이종태. 한국인의 한약재 복용실태 조사 연구. 서울:식품의약품안전청. 2006:91-4.
  4. 박요한 등. 한방의료기관 한약제제 구비현황 조사 연구. 대한한의학방제학회지. 2010;18(1):43-56.
  5. 허준. 동의보감. 서울:남산당. 2007:447.
  6. Prasad KN, et al. Effects of high pressure extraction on the extraction yield, total phenolic content and antioxidant activity of longan fruit pericarp. Innovative Food Science and Emerging Technologies. 2009;10:155-9. https://doi.org/10.1016/j.ifset.2008.11.007
  7. 양희종 등. 반응표면 분석법을 이용한 neohesperidin 생산 수율의 최적화. 생명과학회지. 2010;20(11):1691-6.
  8. 김영식 등. 초음파를 이용한 고삼에 포함된 Genistein 및 Formononetin의 추출. 한국화학공학회지. 2009;47(2):258-61.
  9. 김지혜 등. 팽화에 의한 인삼 유효성분의 변화. 한국응용생명화학회지. 2008;51(3):188-93.
  10. 곽은정. GABA 함량이 높은 갈색 유색미를 이용한 차 개발. 한국식품영양과학회지. 2010;39(8):1201-5.
  11. 한진수 등. 사포닌 함량 및 품질의 증진을 위한 백삼 물추출액 추출 조건. 한국작물학회지. 2009;54(4):458-63.
  12. 정갑섭. 소리쟁이(Rumex crispus) 뿌리로부터 가용성 고형분의 추출특성. 한국환경과학회지. 2011;20(10):1265-72.
  13. Hou K, et al. Modeling and optimization of herb leaching processes. Comput Chem Eng 2000;24:1343-8. https://doi.org/10.1016/S0098-1354(00)00411-7
  14. 천연물화학교재편찬위원회. 천연물화학. 서울:영림사. 2003:236.