Korean Journal of Medicinal Crop Science (한국약용작물학회지)

The Korean Society of Medicinal Crop Science (한국약용작물학회)
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Comparison of the Physiological Activities of Extracts from Different Parts of Prunus sargentii

산벚나무 부위별 추출물의 생리활성 비교

  • Yang, Sun-A (Department of Oriental Medicine Materials, Dongshin University) ;
  • Cho, Joo-Hyun (Department of Oriental Medicine Materials, Dongshin University) ;
  • Pyo, Byoung-Sik (Department of Oriental Medicine Materials, Dongshin University) ;
  • Kim, Sun-Min (Department of Oriental Medicine Materials, Dongshin University) ;
  • Lee, Kyoung-In (Biotechnology Industrialization Center, Dongshin University)
  • 양선아 (동신대학교 한약재산업학과) ;
  • 조주현 (동신대학교 한약재산업학과) ;
  • 표병식 (동신대학교 한약재산업학과) ;
  • 김선민 (동신대학교 한약재산업학과) ;
  • 이경인 (동신대학교 생물자원산업화지원센터)
  • Received : 2012.04.16
  • Accepted : 2012.05.27
  • Published : 2012.06.30
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Abstract

In this study, we investigated the antibacterial activity, antioxidative activity and whitening effect of 75% ethanol extracts from different parts of Prunus sargentii. The total phenolic compound content of the branch extract was 277.92 mg/g as the highest level. In the measurement of DPPH radical scavenging ability, $SC_{50}$ values of the cork layer and branch extract were 26.79 ${\mu}g/m{\ell}$ and 30.13 ${\mu}g/m{\ell}$. In nitric oxide (NO) scavenging ability, $SC_{50}$ values of the branch and leaf extract were 49.19 ${\mu}g/m{\ell}$ and 55.55 ${\mu}g/m{\ell}$. All extracts exhibited higher NO scavenging ability than ascorbic acid used as positive control. On the other hand, in antibacterial activity against Staphylococcus epidermidis and Staphylococcus aureus by disc diffusion assay, the pure bark extract showed the highest activity. Moreover, tyrosinase inhibitory activity of cork layer, pure bark and branch extracts showed higher activity than arbutin used as positive control. In the cytotoxicity measurement by MTT assay, leaf extract was exhibited Raw 264.7 cell viabilities of 44.68~61.83% as cytotoxic result in tested concentration. In conclusion, the branch extract of Prunus sargentii will be a functional materials without damage compared to other parts such as pure bark or cork layer in the plant.

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References

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