The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지

Relationship between Heart Rate Variability and Cold-Heat Patternization in Patient with Chronic Constipation

만성변비환자의 한열변증에 따른 심박변이도에 관한 연구

  • Park, Jong-Joo (Dept. of Internal Medicine, Oriental Medical Hospital, Se-Myung University in Chungju) ;
  • Lee, Myung-Su (Dept. of Internal Medicine, Oriental Medical Hospital, Se-Myung University in Chungju) ;
  • Kong, Kyung-Hwan (Dept. of Internal Medicine, Oriental Medical Hospital, Se-Myung University in Chungju) ;
  • Go, Ho-Yeon (Dept. of Internal Medicine, Oriental Medical Hospital, Se-Myung University in Chungju)
  • 박종주 (세명대학교 충주한방병원 한방내과) ;
  • 이명수 (세명대학교 충주한방병원 한방내과) ;
  • 공경환 (세명대학교 충주한방병원 한방내과) ;
  • 고호연 (세명대학교 충주한방병원 한방내과)
  • Published : 2012.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : The aim of this study was to investigate the relationship between the autonomic nervous system and the cold-heat pattern in patients with chronic constipation. Methods : Subjects with chronic constipation (n=30) and without chronic constipation (n=20) were recruited, interviewed and measured for heart rate variability (HRV). Chronic constipation was defined as functional constipation and Irritable Bowel Syndrome (IBS) with constipation based on Rome III criteria. We surveyed patients' general characteristics, categorized by cold-heat pattern, and took measurement of HRV for 5 minutes. Analysis was conducted among these three indices. Results : Women accounted for most of the subjects with chronic constipation (96.7%). In groups with or without constipation, the number of cold patterns was more than of heat patterns. The mean heart rate of subjects without chronic constipation was significantly higher than that of subjects with chronic constipation. No other statistical significance was noted among indices of HRV and cold-heat pattern. Conclusions : Through this study, there were few relationships between autonomic nervous system measured by HRV and cold-heat pattern in chronic constipation.

Keywords

References

  1. 가톨릭대학교 의과대학 소화기내과. 소화기내과학. 서울: 한우리; 2001, p. 6.
  2. 박무인, 신정은, 명승재, 허규찬, 최차환, 정성애, 등, 대한소화기 기능성질환 운동학회. 변비 치료에 관한 임상진료지침. 대한소화기학회지 2011; 57(2):100-14.
  3. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006;130(5): 1480-91. https://doi.org/10.1053/j.gastro.2005.11.061
  4. 전국한의과대학 비계내과학교실. 비계내과학. 서울: 군자출판사; 2008, p. 189-96.
  5. 윤석희, 김형준. 대역 동의보감. 경남: 동의보감출판사; 2005, p. 420-1.
  6. 변영순, 이정인. 여고생의 스트레와 변비에 관한 연구. 기본간호학회지 2003;10(1):23-9.
  7. Heitkemper M, Jarrett M, Cain KC, Burr R, Levy RL, Feld A, et al. Autonomic nervous system function in women with irritable bowel syndrome. Dig Dis Sci 2001;46(6):1276-84. https://doi.org/10.1023/A:1010671514618
  8. Cain KC, Jarrett ME, Burr RL, Hertig VL, Heitkemper MM. Heart rate variability is related to pain severity and predominant bowel pattern in women with irritable bowel syndrome. Neurogastroenterol Motil 2007;19(2):110-8. https://doi.org/10.1111/j.1365-2982.2006.00877.x
  9. Jarrett ME, Burr RL, Cain KC, Rothermel JD, Landis CA, Heitkemper MM. Autonomic nervous system function during sleep among women with irritable bowel syndrome. Dig Dis Sci 2008; 53(3):694-703. https://doi.org/10.1007/s10620-007-9943-9
  10. Mazur M, Furgala A, Jablonski K, Madroszkiewicz D, Ciecko-Michalska I, Bugajski A, et al. Dysfunction of the autonomic nervous system activity is responsible for gastric myoelectric disturbances in the irritable bowel syndrome patients. J Physiol Pharmacol 2007;58(3):131-9.
  11. Dobrek L, Friediger J, Furgala A, Thor PJ. Autonomic nervous system activity in IBS patients estimated by heart rate variability (HRV). Przegl Lek 2006;63(9):743-7.
  12. 박영재, 남동현, 박영배. 변증과 자율신경기능의 상관성 연구. 대한한의진단학회지 2002;6(1): 123-34.
  13. 이태권, 최경미, 박영재, 박영배. 증상과 맥박변이도와의 상관성 연구. 대한한의진단학회지 2003; 7(2):83-100.
  14. 이상범, 최경미, 박영배. 설문에 의한 음양성향이 맥박변이도에 미치는 영향. 대한한의진단학회지 2003;7(2):101-16.
  15. 이상범, 최경미, 박영배. 음양성향과 맥파의 관련성에 관한 연구. 대한한의진단학회지 2004; 8(1):137-64.
  16. 송윤경, 임형호, 김호준, 진성순, 송재철, 신현택. 모발미네랄검사와 자율신경기능 및 비만도와의 연관성 연구 - 한의학적 변증 응용을 위한 -. 대한한의학회지 2007;28(1):249-59.
  17. 박재우, 윤성우, 김진성, 류봉하. 만성변비에 대한 홍화약침의 효능 연구. 대한침구학회지 2008; 25(5):127-37.
  18. 백태선, 박영재, 박영배, 박재형, 임재중. 한열변증 설문지와 일반적 건강 검진 결과와의 상호 연관성에 관한 비교 연구. 대한한의진단학회지 2005;9(2):145-52.
  19. 김정룡. 김정룡 소화기계 질환. 서울: 일조각; 2000, p. 42-9.
  20. 김숙경, 박영배. 한열변증 설문지 개발. 대한한의진단학회지 2003;07(1):64-75.
  21. 명승재, 이태희, 허규찬, 최석채, 손정일, 대한소화기 기능성질환 운동학회. 변비의 진단: 체계적인 문헌고찰. 대한소화기학회지 2010;55:316-24.
  22. El-Salhy M. Chronic idiopathic slow transit constipation: pathophysiology and management. Colorectal Dis 2003;5(4):288-96. https://doi.org/10.1046/j.1463-1318.2003.00498.x
  23. Altomare D, Pilot MA, Scott M, Williams N, Rubino M, Ilincic L, et al. Detection of subclinical autonomic neuropathy in constipated patients using a sweat test. Gut 1992;33(11): 1539-43. https://doi.org/10.1136/gut.33.11.1539
  24. Task Force of The European Society of Cardiology and The North American Society of Pacing and Electrophysiology. Heart Rate Variability : Standards of measurement, physiological interpretation, and clinical use. European Heart Journal 1996;17:354-81. https://doi.org/10.1093/oxfordjournals.eurheartj.a014868
  25. Pomeranz B, Macaulay RJ, Caudill MA, Kutz I, Adam D, Gordon D, et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 1985;248:H151-3.
  26. 강석일, 임춘우, 박원태, 소응룡, 송민주, 김연섭. 변비에 대한 천추혈 침구치료의 임상적 연구. 대한침구학회지 2001;18(6):125-34.
  27. 강영록, 김연진, 황치원. 배대승기탕 보류관장을 시행한 중풍변폐 환자 45례에 대한 임상적 고찰. 대한한방내과학회지 2001;21(2):329-36.
  28. Amenta M, Cascio MT, Di Fiore P, Venturini I. Diet and chronic constipation. Benefits of oral supplementation with symbiotic zir fos (Bifidobacterium longum W11 + FOS Actilight). Acta Biomed 2006;77(3):157-62.
  29. Tack J, Muller-Lissner S, Bytzer P, Corinaldesi R, Chang L, Viegas A, et al. A randomized controlled trial assessing the efficacy and safety of repeated tegaserod therapy in women with irritable bowel syndrome with constipation. Gut 2005;54(12):1707-13. https://doi.org/10.1136/gut.2005.070789
  30. 김숙경, 남동현, 박영배. 한열변증 설문지 개발을 위한 타당성 연구(I). 대한한의진단학회지 2002;6(2):141-56.
  31. 김지은, 박경모, 이승기, 유화승. 건강군과 질환군의 한열지표 차이에 관한 고찰. 동의생리병리학회지 2006;20(1):224-8.
  32. 김지은, 이정찬, 박경모, 강희철, 이승기. 건강인의 표리 한열 변증, HRV, 우울, 불안 지표의 상관성 분석. 동의생리병리학회지 2006;20(2): 482-7.