Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
권호 표지
DOI QR코드

DOI QR Code

Prevention of tooth discoloration associated with triple antibiotics

Triple antibiotics와 관련한 치아 변색의 예방

  • Kim, Bo-Na (Department of Conservative Dentistry, Gangnam Severance Dental Hospital, Yonsei University College of Dentisty) ;
  • Song, Min-Ju (Department of Conservative Dentistry, Gangnam Severance Dental Hospital, Yonsei University College of Dentisty) ;
  • Shin, Su-Jung (Department of Conservative Dentistry, Gangnam Severance Dental Hospital, Yonsei University College of Dentisty) ;
  • Park, Jeong-Won (Department of Conservative Dentistry, Gangnam Severance Dental Hospital, Yonsei University College of Dentisty)
  • 김보나 (연세대학교 치과대학 보존과 강남세브란스치과병원) ;
  • 송민주 (연세대학교 치과대학 보존과 강남세브란스치과병원) ;
  • 신수정 (연세대학교 치과대학 보존과 강남세브란스치과병원) ;
  • 박정원 (연세대학교 치과대학 보존과 강남세브란스치과병원)
  • Received : 2011.12.29
  • Accepted : 2012.03.15
  • Published : 2012.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

Regenerative endodontics has a potential to heal a partially necrotic pulp, which can be beneficial for the continued root development and strengthening of immature teeth. For this purpose, triple antibiotic mixture of ciprofloxacin, metronidazole, and minocycline was recommended as intracanal medicament in an attempt to disinfect the root canal system for revascularization of a tooth with a necrotic pulp. However, discoloration of the tooth was reported after applying this. This case shows the idea for preventing the tooth discoloration using a delivery syringe to avoid the contact between the clinical crown and the antibiotics.

Keywords

References

  1. Jung IY, Lee SJ, Hargreaves KM. Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series. J Endod 2008;34:876-887.
  2. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 2004;30:196-200.
  3. Huang GT. A paradigm shift in endodontic management of immature teeth: conservation of stem cells for regeneration. J Dent 2008;36:379-386.
  4. Windley W 3rd, Teixeira F, Levin L, Sigurdsson A, Trope M. Disinfection of immature teeth with a triple antibiotic paste. J Endod 2005;31:439-443.
  5. Cheek CC, Heymann HO. Dental and oral discolorations associated with minocycline and other tetracycline analogs. J Esthet Dent 1999;11:43-48.
  6. Dodd MA, Dole EJ, Troutman WG, Bennahum DA. Minocycline-associated tooth staining. Ann Pharmacother 1998;32:887-889.
  7. McKenna BE, Lamey PJ, Kennedy JG, Bateson J. Minocycline-induced staining of the adult permanent dentition: a review of the literature and report of a case. Dent Update 1999;26:160-162.
  8. Petrino JA, Boda KK, Shambarger S, Bowles WR, McClanahan SB. Challenges in regenerative endodontics: a case series. J Endod 2010;36:536-541.
  9. Kim JH, Kim Y, Shin SJ, Park JW, Jung IY. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 2010;36:1086-1091.
  10. Tanase S, Tsuchiya H, Yao J, Ohmoto S, Takagi N, Yoshida S. Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics. Application to discolored teeth. J Chromatogr B Biomed Sci Appl 1998; 706:279-285.
  11. Hargreaves KM, Cohen S. Cohen's pathways of the pulp expert consult. 10th ed. St. Louis: Mosby Elsevier; 2011. Chapter 16, Regenerative endodontics; p602-619.
  12. Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report. Int Endod J 2009;42:84- 92.
  13. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J 1996;29:118-124.

Cited by

  1. Treatment of non-vital immature teeth with amoxicillin-containing triple antibiotic paste resulting in apexification vol.40, pp.4, 2015, https://doi.org/10.5395/rde.2015.40.4.322
  2. Triple antibiotic paste: momentous roles and applications in endodontics: a review vol.43, pp.3, 2018, https://doi.org/10.5395/rde.2018.43.e28
  3. Clinical Effectiveness of Different Polishing Systems and Self-Etch Adhesives in Class V Composite Resin Restorations: Two-Year Randomized Controlled Clinical Trial vol.42, pp.1, 2012, https://doi.org/10.2341/16-104-c
  4. Evaluation of the antimicrobial efficacy of two combinations of drugs on bacteria taken from infected primary teeth (in vitro) vol.20, pp.6, 2012, https://doi.org/10.1007/s40368-019-00446-4