Journal of the Korean Society for Precision Engineering (한국정밀공학회지)

Korean Society for Precision Engineering (한국정밀공학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Intraoperative Deep Brain Stimulation on Viscoelastic Properties of Parkinsonian Rigidity during Surgery

파킨슨성 경직의 점탄성에 대한 수술중의 뇌심부 자극의 효과

  • Received : 2012.01.16
  • Accepted : 2012.06.29
  • Published : 2012.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been found to be effective treatment of Parkinson's disease (PD). This study aims to evaluate the effect of DBS for rigidity during DBS surgery. Six Parkinsonian patients who received STN-DBS surgery participated in this study. The examiner imposed flexion and extension of a patient's wrist randomly. Resistance to passive movement was quantified by viscoelastic properties (two damping constants for each of flexion and extension phase and one spring constant throughout both phases). All Viscoelastic constants decreased by DBS (p<0.01). Specifically, reduction in damping constant during flexion ($B_f$) was greater than those of damping constant during extension ($B_e$) and of spring constant (p<0.05). $B_f$ would be appropriate for evaluation of effect of DBS for rigidity during DBS surgery.

Keywords

References

  1. Allen, D. P., Playfer, J. R., Aly, N. M., Duffey, P., Heald, A., Smith, S. L., and Halliday, D. M., "On the use of low-cost computer peripherals for the assessment of motor dysfunction in Parkinson's disease-quantification of bradykinesia using target tracking tasks," IEEE Trans. Neural Syst. Rehabil. Eng., Vol. 15, No. 2, pp. 286-294, 2007. https://doi.org/10.1109/TNSRE.2007.897020
  2. Moore, S. T., MacDougall, H. G., Gracies, J. M., Cohen, H. S., and Ondo, W. G., "Long-term monitoring of gait in Parkinson's disease," Gait Posture, Vol. 26, No. 2, pp. 200-207, 2007. https://doi.org/10.1016/j.gaitpost.2006.09.011
  3. Volkmann, J., Herzog, J., Kopper, F., and Deuschl, G., "Introduction to the programming of deep brain stimulators," Mov. Disord., Vol. 17, No. 3, pp. S181-S187, 2002. https://doi.org/10.1002/mds.10162
  4. Kim, J. H., Kwon, T. H., Koh, S. B., and Park, J. Y., "Parkinsonism-hyperpyrexia syndrome after deep brain stimulation surgery: case report," Neurosurgery, Vol. 66, No. 5, p. E1029, 2010. https://doi.org/10.1227/01.NEU.0000367799.38332.43
  5. Xia, R., Sun, J., and Threlkeld, A. J., "Analysis of interactive effect of stretch reflex and shortening reaction on rigidity in Parkinson's disease," Clin. Neurophysiol., Vol. 120, No. 7, pp. 1400-1407, 2009. https://doi.org/10.1016/j.clinph.2009.05.001
  6. Endo, T., Okuno, R., Yokoe, M., Akazawa, K., and Sakoda, S., "A novel method for systematic analysis of rigidity in Parkinson's disease," Mov. Disord., Vol. 24, No. 15, pp. 2218-2224, 2009. https://doi.org/10.1002/mds.22752
  7. Levin, J., Krafczyk, S., Valkovic, P., Eggert, T., Claassen, J., and Botzel, K., "Objective measurement of muscle rigidity in Parkinsonian patients treated with subthalamic stimulation," Mov. Disord., Vol. 24, No. 1, pp. 57-63, 2009. https://doi.org/10.1002/mds.22291
  8. Fung, V. S., Burne, J. A., and Morris, J. G., "Objective quantification of resting and activated parkinsonian rigidity: a comparison of angular impulse and work scores," Mov. Disord., Vol. 15, No. 1, pp. 48-55, 2000. https://doi.org/10.1002/1531-8257(200001)15:1<48::AID-MDS1009>3.0.CO;2-E
  9. Shapiro, M. B., Vaillancourt, D. E., Sturman, M. M., Metman, L. V., Bakay, R. A., and Corcos, D. M., "Effects of STN DBS on rigidity in Parkinson's disease," IEEE Trans. Neural Syst. Rehabil. Eng., Vol. 15, No. 2, pp. 173-181, 2007. https://doi.org/10.1109/TNSRE.2007.896997
  10. Mak, M. K., Wong, E. C., and Hui-Chan, C. W., "Quantitative measurement of trunk rigidity in parkinsonian patients," J. Neurol., Vol. 254, No. 2, pp. 202-209, 2007. https://doi.org/10.1007/s00415-006-0327-4
  11. Sepehri, B., Esteki, A., Ebrahimi-Takamjani, E., Shahidi, G. A., Khamseh, F., and Moinodin, M., "Quantification of rigidity in Parkinson's disease," Ann. Biomed. Eng., Vol. 35, No. 12, pp. 2196-2203, 2007. https://doi.org/10.1007/s10439-007-9379-6
  12. Patrick, S. K., Denington, A. A., Gauthier, M. J., Gillard, D. M., and Prochazka, A., "Quantification of the UPDRS Rigidity Scale," IEEE Trans. Neural Syst. Rehabil. Eng., Vol. 9, No. 1, pp. 31-41, 2001. https://doi.org/10.1109/7333.918274
  13. Park, B. K., Kwon, Y., Kim, J. W., Lee, J. H., Eom, G. M., Koh, S. B., Jun, J. H., and Hong, J., "Analysis of viscoelastic properties of wrist joint for quantification of parkinsonian rigidity," IEEE Trans. Neural Syst. Rehabil. Eng., Vol. 19, No. 2, pp. 167-176, 2011. https://doi.org/10.1109/TNSRE.2010.2091149
  14. Winter, D. A., "Biomechanics and motor control of human movement, 3rd ed.," John Wiley & Sons Inc., pp. 75-76, 2004.
  15. No, H. J., "Research methods and statistical analysis for Korean SPSS 10.0," Hyungseul Publisher, pp. 204-206, 2001.

Cited by

  1. Quantification of the Effect of Medication and Deep Brain Stimulation on Parkinsonian Rigidity vol.30, pp.5, 2013, https://doi.org/10.7736/KSPE.2013.30.5.559