Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
권호 표지
DOI QR코드

DOI QR Code

Antimicrobial effects of curcumin against pathogenic bacteria in fish

어류의 병원성 세균에 대한 curcumin의 항균효과

  • Heo, Gang-Joon (College of Veterinary Medicine, Chungbuk National University) ;
  • Kang, Jin-Hui (College of Veterinary Medicine, Chungbuk National University) ;
  • Shin, Gee-Wook (Bio-Safety Research Institute and College of Veterinary Medicine, Chonbuk National University)
  • 허강준 (충북대학교 수의과대학) ;
  • 강진휘 (충북대학교 수의과대학) ;
  • 신기욱 (전북대학교 수의과대학 생체안전연구소)
  • Received : 2013.11.26
  • Accepted : 2013.12.20
  • Published : 2013.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

The present study was to investigate anti-microbial effects of curcumin on major bacterial pathogens for farmed fish, such as Aeromonas hydrophila, A. salmonicida subsp. masoucida, A. salmonicida subsp. salmonicida, Edwardsiella tarda, Vibrio vulnificus, V. paraheamolyticus using disk diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests. In disc diffusion test, curcumin exhibited concentration-dependent antimicrobial activities to all bacteria pathogens used in the study. Antimicrobial effects of curcumin was found differently depending on bacterial species when determined by MIC or MBC tests. For examples, E. tarda and A. hydrophila was respectively the most sensitive bacterium for bacteriostatic and bacteriocidal effect of curcumin. Collectively, curcumin could be a potential natural drug for controlling pathogenic bacteria in the aquaculture industry.

Keywords

References

  1. Ammon HPT, Wahl MA. 1991. Pharmacology of Curcumin longa. Planta Medica 57: 1-7. https://doi.org/10.1055/s-2006-960004
  2. Aoki T, Egusa S, Watanabe T. 1973. Detection of $R^{+}$ bacteria in cultured marine fish, yellow tails. J Micobiol Immunol 21: 77-83.
  3. Beuchat LR, Golden DA. 1989. Antimicrobials occurring naturally in foods. Food Technol 43: 134-142.
  4. Blackburn KJ, Mitchell AM, Blackburn HM, Curtis A, Thompson AB. 2010. Evidence of antibiotic resistance in free swimming, top-level marine predatory fishes. J Zoo and Wildlife Med 41: 7-16. https://doi.org/10.1638/2007-0061.1
  5. Chatterjee S, Padwal Desai SR, Thomas P. 1993. Effect of ${\gamma}$-irradiation on the antioxidant activity of tumeric (Curcuma longa L.) extracts. Food Research International 32:487-490.
  6. Cho SW. 1990. Inhibitory effects grapefruit seed extract (DF-100) on growth and toxin prodution of Penicillium islandicum. J Korean Agric Chem Soc 33: 169-173.
  7. Cowan MM. 1999. Plant products as antimicrobial agent. Clin Microbial Rev 12: 564-582.
  8. Gupta B, Ghash B. 1999. Curcuma longa inhibits TNF-${\alpha}$ induced expression of adhesion molecules human umbilicle vein endothelial cells. International J of Immunopharmacology 21: 745-757. https://doi.org/10.1016/S0192-0561(99)00050-8
  9. Han HS, Woo S, Kim DK, Heo BG, Lee, KD. 2010. Effects of composts in the growth, yield and effective components of tumeric (Curcuma Longa L.) Korean J Environ Agric 32: 171-178.
  10. Hughey VL, Johnson EA. 1987. Antimicrobial activity of lysozyme against bacteria involved in food spoilage and food-borne disease. Appl Environ Microbiol 53:2165-2170.
  11. Kang SY, Oh MJ, Shin JA. 2005. Antimicrobial activities of korean marine algae against fish pathogenic bacteria. Korean J Fish Soc 18: 147-156.
  12. Kang WS, Kim JH, Park EJ, Yoon KR. 1998. Antioxidative Property of Turmeric (Curcumae Rhizoma) Ethanol Extract. Korea J Food Sci Technol 30: 266-271.
  13. Khar A, Mubarak A, Pardhasaradhi BVV, Begum Z, Anjun R. 1995. Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cell. FEBS Latters 445: 165-168.
  14. Kim KH, Chun HJ, Han YS. 1998. Screening of antimicrobial activity of the dandelion (Taraxacum platycarpum) extract. Korean J Soc Food Sci 14: 114.
  15. Kim SS, Jang JW, Song JW, Lim SJ, Jeong JB, Lee SM, Kim KW, Son MH, Lee KJ. 2009. Effects of Dietary Supplementation of Alga Mixtures (Hizikia fusiformis and Ecklonia cava) on Innate Immunity and Disease Resistance Against Edwardsiella tarda in Olive Flounder (Paralichthys olivaceus). Korean J Fish Aquat Sci 42: 614-620. https://doi.org/10.5657/kfas.2009.42.6.614
  16. Lee BW, Shin DH. 1991. Antimicrobial effect of some plant extracts and their fractionates for good spoilage microorganisms. Korean Food Sci Technol 23: 205-211.
  17. Lee SG, Cho KH, Lee WC, Kim YS, Bai HS, Koo BH. 1990. Effects of cefotaxime on the hepatic and renal function of Curcuma Rhizoma in Rabbits. Kyung Hee Univ. Med Cont 6: 188-201.
  18. Mazumder A, Raghavan K, Weinstein J, Kohn KW, Pommier Y. 1995. Inhibition of human immunodeficiency virus TYPE-1 integranse by curcumin. Biochemumder Pharmacology 49: 1165-1170. https://doi.org/10.1016/0006-2952(95)98514-A
  19. Moon JS, Hong YG. 2003. Life properties and contents of cumeric as to harvest condition. pp. 102-105.
  20. National Fisheries Research & Development Agency. 2000. p. 204.
  21. Oh DH, Ham SS, Park BK, Ahn C, Yu JY. 1998. Antimicrobial activities of natural medicinal herbs on the food spoilage or food borne disease microorganisms. Korean J Food Sci Technol 30: 957-953.
  22. Park UY, Chang DS, Cho HR. 1992. Antimicrobial effect of Lithospermum erythrorhizon extract. J Korean Soc Food Nutr 21: 97-100.
  23. Purseglove JW, Brown EG, Green CL, Robbins SRJ. 1981. Spices. pp. 100-286. Lonman Inc., New York, NY, USA.
  24. Ryu SR, Han KJ, Jang HD. 2005. Separation and Purification of Effectiveness Components from UIGem (Curcuma longa) & The Test Study of Anticancer Effects that Use Its. Applied Chemistry 9: 69-72.
  25. Selvam R., Subramanian L, Gayathri R, Angayarkanni N. 1995. The antioxidant activity of turmeric (Curcuma longa). J. of Ethnopharmacology 47: 59-67. https://doi.org/10.1016/0378-8741(95)01250-H
  26. Shelef LA, Naglic OA, Bogen DW. 1980. Sensitivity of some common food-borne bacteria to the spices sage, rosemary and allspice. J Food Sci 45: 1042-1044. https://doi.org/10.1111/j.1365-2621.1980.tb07508.x
  27. Song JH, Kwon HD, Lee WK, Park IH. 1998. Antimicrobial activity and composition of extract from Smilax china root. J Soc Food Sci Nutr 27: 574-584.

Cited by

  1. Determination of Mass Culture Method of Marine-derived Micro Organism, Bacillus sp. 2-4 (KCCMI 11107P) with Antimicrobial Acitivity vol.30, pp.1, 2018, https://doi.org/10.13000/JFMSE.2018.02.30.1.123
  2. 넙치(Paralichthys olivaceus)의 비특이적 면역반응 및 병 저항성에 대한 Bacillus subtilis MD-02의 효과 vol.47, pp.1, 2019, https://doi.org/10.4014/mbl.1807.07003