Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Psychopathological Profile of Women with Breast Cancer Based on the Symptom Checklist-90-R

  • Pan, Xiong-Fei (Cancer Institute & Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Fei, Man-Dong (Cancer Institute & Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Zhang, Kenneth Y. (University of California San Diego) ;
  • Fan, Zhen-Lie (Cancer Institute & Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Fu, Feng-Huan (Cancer Institute & Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College) ;
  • Fan, Jin-Hu (Cancer Institute & Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College)
  • Published : 2013.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: With effective early treatments, many breast cancer patients suffer from psychological distress due to adverse effects and lifelong physical disfigurement. Our study aimed to evaluate the psychopathological profile of breast cancer patients in comparison with healthy women and explored demographic correlates. Method: We consecutively enrolled breast cancer patients who came to the hospital for follow-up or rehabilitation care after primary treatment, and healthy female relatives or friends of inpatients in the Cancer Institute of Chinese Academy of Medical Sciences between August 30, 2010 and January 1, 2012. Psychopathological profile was assessed based on the Symptom Checklist-90-R (SCL-90-R) for patients and controls. We compared demographics such as age, ethnicity, education, marriage, and occupation, and incorporated these data plus cancer status for the association with the general SCL-90-R index and scores for 9 major symptom dimensions in multiple regression analysis. Results: We surveyed a total of 291 female breast cancer patients and 531 healthy women. The average age was $55.1{\pm}6.40$ years for breast cancer patients and $43.1{\pm}12.8$ for healthy controls (P<0.01). The mean survival was 5.20 years for cancer patients (range, 0.60-9.90 years). There were statistically significant differences in education, marriage, and occupation between the two groups (P<0.01). General index ($1.45{\pm}0.45$ versus $1.32{\pm}0.37$) and 8 dimension scores (excluding anxiety) on SCL-90-R were significantly higher in patients (P<0.05). Multiple regression analysis showed that the breast cancer status was positively correlated with general SCL-90-R index and 6 dimension scores (excluding the anxiety, phobic anxiety and paranoid ideation dimensions) (P<0.05). Regression coefficients ranged from 0.10 (depression) to 0.19 (somatization). Higher interpersonal sensitivity was noticed in single women compared to married women. Conclusions: Chinese patients with breast cancer demonstrate greater psychopathology compared to healthy controls. The breast cancer status is an independent contributing factor to the general psychopathological profile. Breast cancer patients should be given particular counseling and care to alleviate their psychological distress.

Keywords

References

  1. Bian JS, Jing XX, Zhuang N (2008). Symptom Checklist-90 as a tool in mental health research: revisiting the issues (Chinese). Chinese J Health Psychol, 16, 231-3.
  2. Chen SC, Li ZQ, Zheng LW, Wu PC (2002). Psychological condition of breast cancer patients with surgery based on the SCL-90 survey (Chinese). Occupation Health, 18, 135.
  3. Chen WQ, Zheng RS, Zeng HM, et al (2013). Incidence and mortality of breast cancer in China, 2008. Thoracic Cancer, 4, 59-65. https://doi.org/10.1111/j.1759-7714.2012.00165.x
  4. Chu QZ, Li JM (2006). Study on psychological condition of patatients with breast cancer and correlated factors (Chinese). J Med Forum, 27, 38-40.
  5. Fafouti M, Paparrigopoulos T, Zervas Y, et al (2010). Depression, anxiety and general psychopathology in breast cancer patients: a cross-sectional control study. In Vivo, 24, 803-10.
  6. Fan L, Zheng Y, Yu KD, et al (2009). Breast cancer in a transitional society over 18 years: trends and present status in Shanghai, China. Breast Cancer Res Treat, 117, 409-16. https://doi.org/10.1007/s10549-008-0303-z
  7. Feng ZZ, Zhang DJ (2001). Validity of the Chinese version of Symptom Checklist-90 (Chinese). J Third Military Med Univ, 23, 481-3.
  8. Ferlay J, Shin HR, Bray F, et al (2010) GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet], Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr, accessed on 25/2/2013.
  9. Gandubert C, Carriere I, Escot C, et al (2009). Onset and relapse of psychiatric disorders following early breast cancer: a case-control study. Psychooncology, 18, 1029-37. https://doi.org/10.1002/pon.1469
  10. Ganz PA (2008). Psychological and social aspects of breast cancer. Oncology (Williston Park), 22, 642-6.
  11. Hjerl K, Andersen EW, Keiding N, et al (2003). Depression as a prognostic factor for breast cancer mortality. Psychosomatics, 44, 24-30. https://doi.org/10.1176/appi.psy.44.1.24
  12. Howlader N, Noone A, Krapcho M, et al (2013). SEER Cancer Statistics Review, 1975-2010. Bethesda, MD, http://seer.cancer.gov/csr/1975_2010/, based on November 2012 SEER data submission, posted to the SEER web site, April 2013, National Cancer Institute.
  13. Jin H, Wu WY, Zhang MY (1986). Preliminary results of SCL-90 in healthy Chinese (Chinese). Chinese Journal of Nervous and Mental Diseases 12, 260-3.
  14. Kissane DW, Grabsch B, Love A, et al (2004). Psychiatric disorder in women with early stage and advanced breast cancer: a comparative analysis. Aust N Z J Psychiatry, 38, 320-6. https://doi.org/10.1080/j.1440-1614.2004.01358.x
  15. Knobf MT (2007). Psychosocial responses in breast cancer survivors. Semin Oncol Nurs, 23, 71-83. https://doi.org/10.1016/j.soncn.2006.11.009
  16. Knobf MT (2011). Clinical update: psychosocial responses in breast cancer survivors. Semin Oncol Nurs, 27, e1-e14. https://doi.org/10.1016/S0749-2081(11)00052-0
  17. Li J, Zhang BN, Fan JH, et al (2011). A nation-wide multicenter 10-year (1999-2008) retrospective clinical epidemiological study of female breast cancer in China. BMC Cancer, 11, 364. https://doi.org/10.1186/1471-2407-11-364
  18. Manne SL, Ostroff JS, Norton TR, et al (2006). Cancer-related relationship communication in couples coping with early stage breast cancer. Psychooncology, 15, 234-47. https://doi.org/10.1002/pon.941
  19. National Office for Cancer Prevention and Control of the Chinese Ministry of Health (2010). National survey on cancer mortality in China. Beijing, The People's Health Press.
  20. Porter P (2008). “Westernizing” women’s risks? Breast cancer in lower-income countries. N Engl J Med, 358, 213-6. https://doi.org/10.1056/NEJMp0708307
  21. Sadler GR, Wang K, Wang M, Ko CM (2000). Chinese women: behaviors and attitudes toward breast cancer education and screening. Womens Health Issues, 10, 20-6. https://doi.org/10.1016/S1049-3867(99)00046-8
  22. Singh U, Verma N (2007). Psychopathology among female breast cancer patients. J Indian Academy Applied Psychol, 33, 61-71.
  23. Tan SM, Evans AJ, Lam TP, Cheung KL (2007). How relevant is breast cancer screening in the Asia/Pacific region? Breast, 16, 113-9. https://doi.org/10.1016/j.breast.2006.08.005
  24. Tang QP, Cheng ZH, Yuan AH, Deng YL (1999). The use and reanalysis of SCL-90 in China (Chinese). Chinese J Clin Psychol, 7, 16-20.
  25. Van’t Spijker A, Trijsburg RW, Duivenvoorden HJ (1997). Psychological sequelae of cancer diagnosis: a meta-analytical review of 58 studies after 1980. Psychosom Med, 59, 280-93. https://doi.org/10.1097/00006842-199705000-00011
  26. Wang Q, Li J, Zheng S, et al (2012). Breast cancer stage at diagnosis and area-based socioeconomic status: a multicenter 10-year retrospective clinical epidemiological study in China. BMC Cancer, 12, 122. https://doi.org/10.1186/1471-2407-12-122
  27. Wang ZY (1984). Introduction to the Symptom Checklist-90 (Chinese). Shanghai Archieves Psychiatry, 2, 68-70.
  28. Wimberly SR, Carver CS, Laurenceau JP, et al (2005). Perceived partner reactions to diagnosis and treatment of breast cancer: impact on psychosocial and psychosexual adjustment. J Consult Clin Psychol, 73, 300-11. https://doi.org/10.1037/0022-006X.73.2.300
  29. Zhang W, Qian QZ (2008). The psychological status and effects of intervention on patients with breast cancer (Chinese). China J Health Psychol, 16.
  30. Zhang YF (2002). Psychological profile of breast cancer patients and associated factors (Chinese). Chinese J Clin Rehab, 6, 2144-5.
  31. Zheng S, Bai JQ, Li J, et al (2012). The pathologic characteristics of breast cancer in China and its shift during 1999-2008: a national-wide multicenter cross-sectional image over 10 years. Int J Cancer, 131, 2622-31. https://doi.org/10.1002/ijc.27513

Cited by

  1. Comfort and Anxiety Levels of Women with Early Stage Breast Cancer Who Receive Radiotherapy vol.15, pp.5, 2014, https://doi.org/10.7314/APJCP.2014.15.5.2109
  2. Effect of Perceived Social Support on Psychosocial Adjustment of Turkish Patients with Breast Cancer vol.15, pp.8, 2014, https://doi.org/10.7314/APJCP.2014.15.8.3429
  3. Reliability and validity assessment of the revised Symptom Checklist 90 for alopecia areata patients in China vol.42, pp.10, 2015, https://doi.org/10.1111/1346-8138.12976
  4. Relationship Between Socio-Demographic Features, Work-Related Conditions, and Level of Anxiety Among Turkish Primary Health Care Workers vol.63, pp.11, 2015, https://doi.org/10.1177/2165079915593249
  5. Gender differences in cancer-related distress in Japan: a retrospective observation study vol.10, pp.1, 2016, https://doi.org/10.1186/s13030-016-0062-8
  6. Mediating effect of coping styles on the association between psychological capital and psychological distress among Chinese nurses: a cross-sectional study vol.24, pp.2-3, 2017, https://doi.org/10.1111/jpm.12350
  7. A comparison of psychosocial care preferences of breast cancer women in Mainland China and Hong Kong vol.28, pp.2, 2019, https://doi.org/10.1002/pon.4947