DOI QR코드

DOI QR Code

Reasons for Variation in Sensitivity and Specificity of Visual Inspection with Acetic Acid (VIA) for the Detection of Pre-Cancer and Cancer Lesions of Uterine Cervix

  • Parashari, Aditya (Division of Clinical Research, Institute of Cytology and Preventive Oncology (ICMR)) ;
  • Singh, Veena (Division of Clinical Research, Institute of Cytology and Preventive Oncology (ICMR))
  • Published : 2013.12.31

Abstract

Alternative strategies such as visual inspection of cervix with acetic acid, are real time, economical and easily implemented methods for cervical cancer screening. However, variable sensitivity and specificity have been observed in various community based studies. The possible reasons could include variation in man power training, light source used for visualization, and preparation of diluted (4-5%) acetic acid and its storage. A standardized protocol for training, teaching material (easy to understand in the local language) for trainees, supervision and reinforcement by intermittent and supplementary training to check the quality of their observation, a standard protocol for preparation dilute acetic acid and its storage and a standard good light source (equivalent to day light) are needed to minimize the variation in sensitivity and specificity of VIA in community settings.

Keywords

References

  1. Fei HL, Cheng YF, Cheng XD, et al (2011). Evaluation of five screening methods for an early detection of cervical cancer and its precancerous lesions in Zhejiang province. Zhonghua Yi Xue. 91, 309-12.
  2. Parashari Aditya, Singh V, Sehgal A, et al (20000. Low-cost technology for screening uterine cervical cancer. Bull WHO. 78, 964-7.
  3. Sankarnarayanan R, Nessa A, Esmy PO, et al (2012). Visual inspection methods for cervical cancer prevention. Best Pract Res Clin Obstet Gynaecol, 26, 221-32. https://doi.org/10.1016/j.bpobgyn.2011.08.003
  4. Sangwa-Lugoma G, Mahmud S, Nasr SH, et al (2006). Visual inspection as a cervical cancer screening method in a primary health care setting in Africa. Int J Cancer, 119, 1389-95. https://doi.org/10.1002/ijc.21972
  5. Sherigar B, Dalal A, Durdi G, et al (2010). Cervical cancer screening by visual Inspection with acetic acid - interobserver variability between nurse and physician. Asian Pac J Cancer Prev, 11, 619-22.
  6. Singh V, Parashari A, Sehgal A (2012). Man power training for early cervical cancer detection. Acta Obstet Gynecol Scand, 91, 1124-7. https://doi.org/10.1111/j.1600-0412.2012.01449.x
  7. Singh V, Parashari A, Sehgal A (2013). VIA screening for cervical cancer in developing countries: Potential role of the light source. J Obstet Gynaecol, 33, 898-99. https://doi.org/10.3109/01443615.2013.823389

Cited by

  1. A Systematic Review of Economic Aspects of Cervical Cancer Screening Strategies Worldwide: Discrepancy between Economic Analysis and Policymaking vol.15, pp.19, 2014, https://doi.org/10.7314/APJCP.2014.15.19.8229
  2. Cervical Screening Using Visual Inspection with Acetic Acid (VIA) and Treatment with Cryotherapy in Fiji vol.15, pp.24, 2015, https://doi.org/10.7314/APJCP.2014.15.24.10757
  3. Use of Fast Transfer Analysis Cartridges for Cervical Sampling and Real Time PCR Based High Risk HPV Testing in Cervical Cancer Prevention - a Feasibility Study from South India vol.16, pp.14, 2015, https://doi.org/10.7314/APJCP.2015.16.14.5993
  4. Accuracy of Visual Inspection with Acetic acid in Detecting High-Grade Cervical Intraepithelial Neoplasia in Pre- and Post-Menopausal Thai Women with Minor Cervical Cytological Abnormalities vol.16, pp.6, 2015, https://doi.org/10.7314/APJCP.2015.16.6.2327
  5. Determinants of Cervical Cancer Screening Accuracy for Visual Inspection with Acetic Acid (VIA) and Lugol’s Iodine (VILI) Performed by Nurse and Physician vol.12, pp.1, 2017, https://doi.org/10.1371/journal.pone.0170631
  6. Needs for Professional Education to Optimize Cervical Cancer Screenings in Low-Income Countries: a Case Study from Tanzania pp.1543-0154, 2017, https://doi.org/10.1007/s13187-017-1276-6
  7. Feasibility of implementing cervical cancer screening program using smartphone imaging as a training aid for nurses in rural India pp.07371209, 2018, https://doi.org/10.1111/phn.12517