Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지
DOI QR코드

DOI QR Code

Comparative evaluation of NovaMin desensitizer and Gluma desensitizer on dentinal tubule occlusion: a scanning electron microscopic study

  • Received : 2013.04.19
  • Accepted : 2013.11.07
  • Published : 2013.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: In this study, the effect of calcium sodium phosphosilicate (NovaMin) desensitizing agent, which is a powder-based system, and hydroxyethyl methacrylate and glutaraldehyde (Gluma desensitizer), which is liquid-based system, on dentinal tubule occlusion was analyzed by scanning electron microscope. The effects of the above two along with one control group were compared to determine the more effective method of sealing the dentinal tubules after initial application. Methods: Twenty specimens were allocated to each of 3 groups: Control, Gluma desensitizer, and NovaMin. Two additional samples were also prepared and treated with Gluma and NovaMin; these samples were longitudinally fractured. The specimens were prepared from extracted sound human premolars and were stored in 10% formalin at room temperature. The teeth were cleaned of gross debris and then sectioned to provide one to two dentin specimens. The dentin specimens were etched with 6% citric acid for 2 minutes and rinsed in distilled water. Control discs were dried, and the test discs were treated with the desensitizing agents as per the manufacturer's instructions. The discs as well as longitudinal sections were later analyzed under the scanning electron microscope. The proportions of completely occluded, partially occluded, and open tubules within each group were calculated. The ratios of completely and partially occluded tubules to the total tubules for all the groups was determined, and the data was statistically analyzed using nonparametric tests and statistical significance was calculated. Results: NovaMin showed more completely occluded tubules ($0.545{\pm}0.051$) while Gluma desensitizer showed more partially occluded tubules ($0.532{\pm}0.075$). The differences among all the groups were statistically significant ($P{\leq}0.05$). Conclusion: Both materials were effective in occluding dentinal tubules but NovaMin appeared more promising in occluding tubules completely after initial application.

Keywords

References

  1. Banoczy J. Dentine hypersensitivity: general practice considerations for successful management. Int Dent J 2002;52(Suppl 5):366. https://doi.org/10.1002/j.1875-595X.2002.tb00935.x
  2. Johnson RH, Zulqar-Nain BJ, Koval JJ. The effectiveness of an electro-ionizing toothbrush in the control of dentinal hypersensitivity. J Periodontol 1982;53:353-9. https://doi.org/10.1902/jop.1982.53.6.353
  3. Curro FA. Tooth hypersensitivity in the spectrum of pain. Dent Clin North Am 1990;34:429-37.
  4. Bamise CT, Olusile AO, Oginni AO. An analysis of the etiological and predisposing factors related to dentin hypersensitivity. J Contemp Dent Pract 2008;9:52-9.
  5. Dababneh RH, Khouri AT, Addy M. Dentine hypersensitivity - an enigma? A review of terminology, mechanisms, aetiology and management. Br Dent J 1999;187:606-11.
  6. Narhi MV. Responses of pulpal nociceptors to tissue injury and inflammation. In: Addy M, Embery G, Edgar WM, Orchardson R. Tooth wear and sensitivity: clinical advances in restorative dentistry. London: Martin Dunitz; 2000. p.257-66.
  7. Jacobsen PL, Bruce G. Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment. J Contemp Dent Pract 2001;2:1-12.
  8. Orchardson R. Strategies for the management of dentine hypersensitivity. In: Addy M, Embery G, Edgar WM, Orchardson R. Tooth wear and sensitivity: clinical advances in restorative dentistry. London: Martin Dunitz; 2000. p.315-25.
  9. Litkowski L. Pilot clinical and in vitro studies evaluating NovaMin in desensitizing dentifrices [abstract]. Dent Res 1998;77:199.
  10. Absi EG, Addy M, Adams D. Dentine hypersensitivity: a study of the patency of dentinal tubules in sensitive and non-sensitive cervical dentine. J Clin Periodontol 1987;14:280-4. https://doi.org/10.1111/j.1600-051X.1987.tb01533.x
  11. Yoshiyama M, Masada J, Uchida A, Ishida H. Scanning electron microscopic characterization of sensitive vs. insensitive human radicular dentin. J Dent Res 1989;68:1498-502. https://doi.org/10.1177/00220345890680110601
  12. Pashley DH, Carvalho RM. Dentine permeability and dentine adhesion. J Dent 1997;25:355-72. https://doi.org/10.1016/S0300-5712(96)00057-7
  13. West NX. Dentine hypersensitivity: preventive and therapeutic approaches to treatment. Periodontol 2000 2008;48:31-41. https://doi.org/10.1111/j.1600-0757.2008.00262.x
  14. Ling TY, Gillam DG, Barber PM, Mordan NJ, Critchell J. An investigation of potential desensitizing agents in the dentine disc model: a scanning electron microscopy study. J Oral Rehabil 1997;24:191-203. https://doi.org/10.1111/j.1365-2842.1997.tb00313.x
  15. Morris MF, Davis RD, Richardson BW. Clinical efficacy of two dentin desensitizing agents. Am J Dent 1999;12:72-6.
  16. Gillam DG, Mordan NJ, Sinodinou AD, Tang JY, Knowles JC, Gibson IR. The effects of oxalate-containing products on the exposed dentine surface: an SEM investigation. J Oral Rehabil 2001;28:1037-44. https://doi.org/10.1046/j.1365-2842.2001.00775.x
  17. Arrais CA, Chan DC, Giannini M. Effects of desensitizing agents on dentinal tubule occlusion. J Appl Oral Sci 2004;12:144-8. https://doi.org/10.1590/S1678-77572004000200012
  18. Litkowski LJ, Hack GD, Greenspan DC, inventors; US Biomaterials Co., assignee. Compositions containing bioactive glass and their use in treating tooth hypersensitivity. United States patent US 5,735,942. 1998 Apr 7.
  19. Litkowski LJ, Hack GD, Greenspan DC, inventors; US Biomaterials Co., assignee. Methods of treatment using bioactive glass. United States patent US 6,086,374. 2000 Jul 11.
  20. Wefel JS. NovaMin: likely clinical success. Adv Dent Res 2009;21:40-3. https://doi.org/10.1177/0895937409335622
  21. Rajesh KS, Hedge S, Arun Kumar MS, Shetty DG. Evaluation of the efficacy of a 5% calcium sodium phosphosilicate (Novamin) containing dentifrice for the relief of dentinal hypersensitivity: a clinical study. Indian J Dent Res 2012;23:363-7. https://doi.org/10.4103/0970-9290.102228
  22. Kolker JL, Vargas MA, Armstrong SR, Dawson DV. Effect of desensitizing agents on dentin permeability and dentin tubule occlusion. J Adhes Dent 2002;4:211-21.
  23. Schüpbach P, Lutz F, Finger WJ. Closing of dentinal tubules by Gluma desensitizer. Eur J Oral Sci 1997;105(5 Pt 1):414-21. https://doi.org/10.1111/j.1600-0722.1997.tb02138.x
  24. In-Vitro evaluation of NovaMin root conditioner. Internal Research Report [Internet]. Alachua (FL): NovaMin Technology Inc.; [cited 2013 Mar 15]. Available from: http://www.oralscience.ca/en/documentation/articles/tooth_paste/In-Vitro-Evaluation-of-NovaMin-Root-Conditioner.pdf.
  25. Du Min Q, Bian Z, Jiang H, Greenspan DC, Burwell AK, Zhong J, et al. Clinical evaluation of a dentifrice containing calcium sodium phosphosilicate (novamin) for the treatment of dentin hypersensitivity. Am J Dent 2008;21:210-4.
  26. de Assis Cde A, Antoniazzi RP, Zanatta FB, Rosing CK. Efficacy of Gluma Desensitizer on dentin hypersensitivity in periodontally treated patients. Braz Oral Res 2006;20:252-6. https://doi.org/10.1590/S1806-83242006000300013

Cited by

  1. Occluding Effect of the Application of Fluoride Compounds and Desensitizers on Dentinal Tubules vol.16, pp.4, 2013, https://doi.org/10.17135/jdhs.2016.16.4.272
  2. Effect of GLUMA desensitizer on the retention of full metal crowns cemented with Rely X U200 self-adhesive cement vol.8, pp.5, 2016, https://doi.org/10.4047/jap.2016.8.5.404
  3. Efficacy of Diode Laser and Gluma on Post‐Preparation Sensitivity: A Randomized Split‐Mouth Clinical Study vol.28, pp.6, 2016, https://doi.org/10.1111/jerd.12230
  4. Evaluation of ex vivo effectiveness of commercial desensitizing dentifrices vol.9, pp.4, 2013, https://doi.org/10.4317/jced.53040
  5. Effects of different desensitizers and lasers on dentine tubules: An in‐vitro analysis vol.80, pp.7, 2017, https://doi.org/10.1002/jemt.22859
  6. Performance of a bioglass-based dentine desensitizer under lactid acid exposition: an in-vitro study vol.18, pp.None, 2013, https://doi.org/10.1186/s12903-018-0642-z
  7. Preventive Use of a Resin-based Desensitizer Containing Glutaraldehyde on Tooth Sensitivity Caused by In-office Bleaching: A Randomized, Single-blind Clinical Trial vol.43, pp.5, 2013, https://doi.org/10.2341/17-020-c
  8. Comparative Evaluation of the Remineralizing Potential of Commercially Available Agents on Artificially Demineralized Human Enamel: An In vitro Study vol.10, pp.4, 2019, https://doi.org/10.4103/ccd.ccd_679_18
  9. Four-Session Protocol Effectiveness in Reducing Cervical Dentin Hypersensitivity: A 24-Week Randomized Clinical Trial vol.37, pp.2, 2013, https://doi.org/10.1089/photob.2018.4477
  10. In Vitro Effect of Innovative Desensitizing Agents on Dentin Tubule Occlusion and Erosive Wear vol.44, pp.2, 2013, https://doi.org/10.2341/17-284-l
  11. Clinical Evaluation of Nd:YAG Laser With and Without Dentin Bonding Agent for the Treatment of Occlusal Hypersensitivity vol.44, pp.3, 2013, https://doi.org/10.2341/17-265-c
  12. Nd:YAG laser and calcium sodium phosphosilicate prophylaxis paste in the treatment of dentin hypersensitivity: a double-blind randomized clinical study vol.23, pp.8, 2013, https://doi.org/10.1007/s00784-018-2759-5
  13. Therapeutic Management of Demineralized Dentin Surfaces Using a Mineralizing Adhesive To Seal and Mineralize Dentin, Dentinal Tubules, and Odontoblast Processes vol.5, pp.10, 2013, https://doi.org/10.1021/acsbiomaterials.9b00619
  14. Efficacy of MI Paste® on Bleaching-Related Sensitivity: Randomized Clinical Trial vol.2021, pp.None, 2013, https://doi.org/10.1155/2021/9963823
  15. Study on Occluding Dentinal Tubules with a Nanosilver-Loaded Silica System In Vitro vol.6, pp.30, 2021, https://doi.org/10.1021/acsomega.1c02123
  16. Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds vol.15, pp.3, 2013, https://doi.org/10.1055/s-0041-1725576