Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
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Tooth Loss May Predict Poor Cognitive Function in Community-Dwelling Adults without Dementia or Stroke: The PRESENT Project

  • Park, Hyunyoung (Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine) ;
  • Suk, Seung-Han (Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine) ;
  • Cheong, Jin-Sung (Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine) ;
  • Lee, Hak-Seung (Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine) ;
  • Chang, Hyuk (Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Clinical Medicine) ;
  • Do, Seung-Yeon (Division of Health and Nutrition Survey, Korea Centers for Disease Control and Prevention) ;
  • Kang, Ji-Sook (Department of Nursing, Wonkwang University College of Medicine)
  • Received : 2012.04.26
  • Accepted : 2013.07.29
  • Published : 2013.10.10
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Abstract

Periodontal disease is a potential predictor of stroke and cognitive impairment. However, this association is unclear in adults aged 50 yr and above without a history of stroke or dementia. We evaluated the association between the number of teeth lost, indicating periodontal disease, and cognitive impairment in community-dwelling adults without any history of dementia or stroke. Dental examinations were performed on 438 adults older than 50 yr (315 females, mean age $63{\pm}7.8$ yr; 123 males, mean age $61.5{\pm}8.5$ yr) between January 2009 and December 2010. In the unadjusted analysis, odds ratios (OR) of cognitive impairment based on MMSE score were 2.46 (95% CI, 1.38-4.39) and 2.7 (95% CI, 1.57-4.64) for subjects who had lost 6-10 teeth and those who had lost more than 10 teeth, respectively, when compared with subjects who had lost 0-5 teeth. After adjusting for age, education level, hypertension, diabetes, hyperlipidemia, and smoking, the relationship remained significant (OR, 2.0; 95% CI, 1.08-3.69, P=0.027 for those with 6-10 teeth lost; OR, 2.26; 95% CI, 1.27-4.02, P=0.006 for those with more than 10 teeth lost). The number of teeth lost is correlated with cognitive impairment among community-dwelling adults aged 50 and above without any medical history of stroke or dementia.

Keywords

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