Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Antimicrobial and Anti-oral Malodor Efficacy of Schizandra chinensis Extracts against Oral Pathogens

오미자 추출물의 구강병원균에 대한 항균효과 및 구취억제 효과

  • Heo, Nam Suk (Department of Dental Hygiene, Masan University) ;
  • Choi, Hye Jung (Department of Biology and Interdisciplinary Program for Biotechnology, Changwon National University) ;
  • Hwang, Su Mi (Department of Clinical Pathology, Masan University) ;
  • Choi, Young Whan (Department of Horticultural Bioscience, Pusan National University) ;
  • Lee, Young Geun (Department of Food Science and Technology, Pusan National University) ;
  • Joo, Woo Hong (Department of Biology and Interdisciplinary Program for Biotechnology, Changwon National University)
  • 허남숙 (마산대학교 치위생학과) ;
  • 최혜정 (창원대학교 생명공학협동과정) ;
  • 황수미 (마산대학교 임상병리과) ;
  • 최영환 (부산대학교 원예생명자원학과) ;
  • 이영근 (부산대학교 식품공학과) ;
  • 주우홍 (창원대학교 생명공학협동과정)
  • Received : 2012.06.25
  • Accepted : 2012.11.23
  • Published : 2013.03.30
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Abstract

This study was conducted to investigate the antimicrobial and anti-oral malodor effect of Schizandra chinensis extracts against oral pathogens. S. chinensis methanol (MeOH) extract showed better antimicrobial activities against oral pathogens than the S. chinensis hot water extract did. In particular, ethylacetate (EA) fraction of S. chinensis MeOH extract had the greatest effects against Streptococcus mutans, S. sanguinis, S. salivaris subsp. thermophols and Porphyromons gingivalis. The anti-malodor effect of S. chinensis against the generation of volatile sulfur compounds (VSC), such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, was estimated using oral chroma in a practical study. The results showed that 2% MeOH extract of S. chinensis against the production of hydrogen sulfide, methyl mercaptan, and dimethyl sulfide had inhibitions of 91.15, 78.72 and 71.58%, respectively. These results showed that Schizandra chinensis extract had antimicrobial activity against several oral pathogens and exhibited significant effects on the inhibition of VSCs. Thus, Schizandra chinensis extract could be an alternative to available synthetic chemicals and oral hygiene products.

본 연구는 오미자 추출물의 구강병원균에 대한 항균활성과 항구취 효과를 조사하기 위해 수행되었다. 오미자 MeOH 추출물이 열수추출물에 비해 구강병원균에 대한 항균활성이 더 뛰어난 것으로 나타났다. 특히 MeOH 추출물의 EA 분획물은 Streptococcus mutans, S. sanguinis, S. salivaris subsp. thermophols 그리고 Porphyromons gingivalis에 대한 활성이 뛰어난 것으로 조사되었다. 오미자 2% MeOH 추출물의 항구취 효과를 oral chroma를 이용한 실제실험에서 측정한 결과, 황화수소, 메틸머캅탄 그리고 황화디메틸을 각각 91.15, 78.72 그리고 71.58% 감소시키는 것으로 측정되었다. 본 연구 결과, 오미자 추출물은 몇몇의 구강병원균에 대한 항균활성을 보였고 휘발성 화합물을 억제하는 효과가 뛰어난 것으로 나타났다. 그러므로 오미자의 추출물은 항균용 합성약품과 구강위생용품을 대체할 수 있는 소재로 판단된다.

Keywords

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