DOI QR코드

DOI QR Code

Emergence of GII.4 Sydney Norovirus in South Korea During the Winter of 2012-2013

  • Kim, Hyun Soo (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Hyun, Jeongwon (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Kim, Han-Sung (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Kim, Jae-Seok (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Song, Wonkeun (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Lee, Kyu Man (Department of Laboratory Medicine, Hallym University College of Medicine)
  • Received : 2013.08.20
  • Accepted : 2013.09.10
  • Published : 2013.11.28

Abstract

Norovirus is the major cause of acute gastroenteritis worldwide. Between November 2012 and June 2013, 1718 stool samples were requested for norovirus antigen testing in the metropolitan areas of South Korea, and 91 samples were genotyped. The norovirus antigen-positive rate peaked at 52.8% in December 2013. A novel norovirus GII.4 variant, GII.4 Sydney 2012, was the most frequently found genotype (60.4%) during this period. This study demonstrates that norovirus activity increased during the winter of 2012-2013 in South Korea and that norovirus GII.4 Sydney 2012 was the cause of the norovirus epidemic during this period.

Keywords

References

  1. Barclay L, Wikswo M, Gregoricus N, Vinjé J, Lopman B, Parashar U, et al. 2013. Emergence of new norovirus strain GII.4 Sydney-United States 2012. MMWR 62: 55-56
  2. Eden J, Tanaka MM, Boni MF, Rawlinson WD, White PA. 2013. Recombination within the pandemic norovirus GII.4 lineage. J. Virol. 87: 6270-6282. https://doi.org/10.1128/JVI.03464-12
  3. Han TH, Kim CH, Chung JY, Park SH, Hwang ES. 2011. Emergence of norovirus GII-4/2008 variant and recombinant strains in Seoul, Korea. Arch. Virol. 156: 323-329. https://doi.org/10.1007/s00705-010-0844-4
  4. Hasing ME, Lee BE, Preiksaitis JK, Tellier R, Honish L, Senthilselvan A, et al. 2013. Emergence of a new norovirus GII.4 variant and changes in the historical biennial pattern of norovirus outbreak activity in Alberta Canada, from 2008-2013. J. Clin. Microbiol. 51: 2204-2211. https://doi.org/10.1128/JCM.00663-13
  5. Higgins RR, Beniprashad M, Cardona M, Masney S, Low DE, Gubbay JB. 2011. Evaluation and verification of the Seeplex Diarrhea-V ACE assay for simultaneous detection of adenovirus, rotavirus, and norovirus genogroups I and II in clinical stool specimens. J. Clin. Microbiol. 49: 3154-3162. https://doi.org/10.1128/JCM.00599-11
  6. Hoa Tran TN, Trainor E, Nakagomi T, Cunliffe NA, Nakagomi O. 2013. Molecular epidemiology of noroviruses associated with acute sporadic gastroenteritis in children: global distribution of genogroups, genotypes and GII.4 variants. J. Clin. Virol. 56: 185-193
  7. Huh JW, Kim W-H, Moon SG, Lee JB, Lim YH. 2009. Viral etiology and incidence associated with acute gastroenteritis: a 5-year survey in Gyeonggi province, South Korea. J. Clin. Virol. 44: 152-156. https://doi.org/10.1016/j.jcv.2008.11.016
  8. Kim EJ, Kim MS, Cheon DS, Song MO, Kim MY, Park SH, et al. 2008. Genetic distribution of human noroviruses detected from acute gastroenteritis patients in Seoul. Korean J. Microbiol. 44: 135-139.
  9. Kroneman A, Vega E, Vennema H, Vinjé J, White PA, Hansman G, et al. 2013. Proposal for a unified norovirus nomenclature and genotyping. Arch. Virol. 158: 2059-2068. https://doi.org/10.1007/s00705-013-1708-5
  10. Kroneman A, Vennema H, Deforche K, Avoort HV, Pennaranda S, Oberste MS, et al. 2001. An automated genotyping tool for enteroviruses and noroviruses. J. Clin. Virol. 51: 121-125.
  11. Lim KL, Eden J, Oon LLE, White PA. 2013. Molecular epidemiology of norovirus in Singapore 2004-2011. J. Med. Virol. 85: 1842-1851. https://doi.org/10.1002/jmv.23669
  12. Morillo SG, Luchs A, Cilli A, Ribeiro CD, Calux SJ, Carmona Rde C, et al. 2011. Norovirus 3rd generation kit: an improvement for rapid diagnosis of sporadic gastroenteritis cases and valuable for outbreak detection. J. Virol. Methods 173: 13-16. https://doi.org/10.1016/j.jviromet.2010.12.017
  13. Park DJ, Kim JS, Park JY, Kim HS, Song W, Kim HS, et al. 2010. Epidemiological analysis of norovirus infection between March 2007 and February 2010. Korean J. Lab. Med. 30: 647-653. https://doi.org/10.3343/kjlm.2010.30.6.647
  14. Park K, Yeo S, Jeong H, Baek K, Kim D, Shin M, et al. 2012. Updates on the genetic variations of norovirus in sporadic gastroenteritis in Chungnam Korea, 2009-2010. Virol. J. 9: 29. https://doi.org/10.1186/1743-422X-9-29
  15. Patel MM, Widdowson MA, Glass RI, Akazawa K, Vinjé J, Parashar UD. 2008. Systematic literature review of role of noroviruses in sporadic gastroenteritis. Emerg. Infect. Dis. 14: 1224-1231. https://doi.org/10.3201/eid1408.071114
  16. van Beek J, Ambert-Balay K, Botteldoorn N, Eden JS, Fonager J, Hewitt J, et al. 2013. Indications for worldwide increased norovirus activity associated with emergence of a new variant of genotype II.4, late 2012. Euro Surveill. 18: 8-9.
  17. van Beek J, Kroneman A, Vennema H, Koopmans M. 2013. Norovirus Molecular Platform: Noronet Report, April 2013. Available at http://www.rivm.nl/dsresource?objectid=rivmp:204484&type=org&disposition=inline&ns_nc=1.

Cited by

  1. Development of Enhanced Primer Sets for Detection of Norovirus vol.2015, pp.None, 2013, https://doi.org/10.1155/2015/103052
  2. Molecular Epidemiology of Human Norovirus in Korea in 2013 vol.2015, pp.None, 2015, https://doi.org/10.1155/2015/468304
  3. Molecular epidemiology of norovirus in South Korea vol.48, pp.2, 2013, https://doi.org/10.5483/bmbrep.2015.48.2.254
  4. Molecular Characteristics of Noroviruses Genogroup I and Genogroup II Detected in Patients With Acute Gastroenteritis vol.35, pp.2, 2013, https://doi.org/10.3343/alm.2015.35.2.242
  5. Re-emergence of a GII.4 Norovirus Sydney 2012 Variant Equipped with GII.P16 RdRp and Its Predominance over Novel Variants of GII.17 in South Korea in 2016 vol.9, pp.2, 2017, https://doi.org/10.1007/s12560-017-9278-4
  6. Full-genome sequence analysis of an uncommon norovirus genotype, GII.21, from South Korea vol.145, pp.11, 2013, https://doi.org/10.1017/s0950268817001273
  7. Phylogenetic characterization of norovirus strains detected from sporadic gastroenteritis in Seoul during 2014–2016 vol.10, pp.None, 2018, https://doi.org/10.1186/s13099-018-0263-8
  8. Pathogenesis of Human Norovirus Genogroup II Genotype 4 in Post-Weaning Gnotobiotic Pigs vol.28, pp.12, 2018, https://doi.org/10.4014/jmb.1809.09061
  9. Full-genome sequences of GII.13[P21] recombinant norovirus strains from an outbreak in Changsha, China vol.165, pp.7, 2020, https://doi.org/10.1007/s00705-020-04643-1