Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Prevalence of Depression in Breast Cancer Survivors: a Systematic Review of Observational Studies

  • Zainal, Nor Zuraida (Psychological Medicine Research Group of University Malaya (PARADIGM), Faculty of Medicine, University of Malaya) ;
  • Nik-Jaafar, Nik Ruzyanei (Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre) ;
  • Baharudin, Azlin (Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre) ;
  • Sabki, Zuraida Ahmad (Psychological Medicine Research Group of University Malaya (PARADIGM), Faculty of Medicine, University of Malaya) ;
  • Ng, Chong Guan (Psychological Medicine Research Group of University Malaya (PARADIGM), Faculty of Medicine, University of Malaya)
  • Published : 2013.04.30
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Abstract

Background: Depression is common in breast cancer patients. The aim of this paper was to make a systematic review of its prevalence and associated factors oin breast cancer survivors. Materials and Methods: An extensive systematic electronic review (PUBMED, CINAHL, PsyINFO and Ovid) and handsearch were carried out to retrieve published articles up to November 2012, using Depression OR Dysthymia AND (Cancer OR Tumor OR Neoplasms as the keywords. Information about the design of the studies, measuring scale, characteristics of the participants, prevalence of depression and its associated factors from the included studies were extracted and summarized. Results: We identified 32 eligible studies that recruited 10,826 breast cancer survivors. Most were cross-sectional or prospective designed. The most frequent instrument used to screen depression was the Center for Epidemiological Studies for Depression (CES-D, n=11 studies) followed by the Beck Depression Inventory (BDI, n=6 studies) and the Hospital Anxiety and Depression Scale (HADS, n=6 studies). CES-D returned about similar prevalence of depression (median=22%, range=13-56%) with BDI (median=22%, range=17-48%) but higher than HADS (median=10%, range=1-22%). Depression was associated with several socio-demographic variables, cancer-related factors, treatment-related factors, subject psychological factors, lifestyle factors, social support and quality of life. Conclusions: Breast cancer survivors are at risk for depression so that detection of associated factors is important in clinical practice.

Keywords

References

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