Nutrition Research and Practice

The Korean Nutrition Society (한국영양학회)
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Laxative effect of peanut sprout extract

  • Seo, Ji Yeon (School of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Seong Soon (School of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Hyo Jung (Reseacrh Institute for Biological Functions, Chubu University) ;
  • Liu, Kwang-Hyeon (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University) ;
  • Lee, Hak-Yong (Huvet Co. Ltd.) ;
  • Kim, Jong-Sang (School of Food Science and Biotechnology, Kyungpook National University)
  • Received : 2012.12.27
  • Accepted : 2013.05.09
  • Published : 2013.08.01
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Abstract

Certain phenolic compounds are known to exhibit laxative properties. Seed sprouts, such as those of peanut, are known to promote de novo biosynthesis of phenolic compounds. This study was conducted to examine the potential laxative properties of 80% (v/v) ethanolic extract of peanut sprout (PSE), which contains a high concentration of phenolic compounds such as resveratrol. For this, SD rats were orally administered PSE while a control group was incubated with saline. Laxative effects were examined in both groups of rats. Constipation induced by loperamide in SD rats was improved by administration of PSE. Constipated rats showed increased intestinal movement of $BaSO_4$ upon administration of PSE compared to the control, and the groups administered 100 or 1,000 mg PSE/kg bw were not significantly different in transit time of the indicator. However, colon length was not statistically different among the experimental groups, although it was longer in the group incubated with 1 g PSE/kg bw compared to other groups. Further, there was no significant difference in stool number among the experimental groups. Taken together, these findings show that PSE has a laxative effect in a rat model of loperamide-induced constipation.

Keywords

References

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