Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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The Effect of Yongyukjowitang Distillate on the Immune Activity of Spleen Cells of Aged Rats

용육조위탕(龍肉調胃湯) 증류액이 노화 흰쥐 비장 세포의 면역활성에 미치는 영향

  • Yi, Jin-Wook (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Daejeon University) ;
  • Jang, Moon-Hee (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Daejeon University) ;
  • Choi, Jae-Song (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Daejeon University) ;
  • Ahn, Taek-Won (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Daejeon University)
  • 이진욱 (대전대학교 한의과대학 사상체질의학) ;
  • 장문희 (대전대학교 한의과대학 사상체질의학) ;
  • 최재송 (대전대학교 한의과대학 사상체질의학) ;
  • 안택원 (대전대학교 한의과대학 사상체질의학)
  • Received : 2013.07.05
  • Accepted : 2013.09.04
  • Published : 2013.09.30
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Abstract

Objectives The purpose of this study was to investigate the effect of Yongyukjowitang(YJT) distillate on the immune activity of spleen cells of aged SD rats. Methods Spleen cells from 10w, 52w, 72w old rats were stimulated with Concanavalin A(Con A) and treated with Vitamin C(Vit.C) or Yongyukjowitang distillate(YJT). After 24 hours, levels of IL-2, IL-4, IL-10, IFN-${\gamma}$ were measured using ELISA in spleen cells. Results and Conclusions 1. The concentration of IL-2, IL-4 in spleen cells of 52 weeks old SD rats(YJT group) significantly decreased in comparison with ConA group. 2. The concentration of IFN-${\gamma}$ in spleen cells of 72 weeks old SD rats significantly increased in comparison with 10 weeks old SD rats(NT group), but decreased in comparison with 10 weeks old SD rats(YJT group). These results suggest that Yongyukjowitang distillate has an effect on the immune activity of spleen cells of aged SD rats.

Keywords

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