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Biological Activity of Aloe Vera Gel and Skin Extracts

알로에 베라 젤 및 껍질 추출물의 생리활성 평가

  • Cho, Eunhye (Research & Development, Natural Choice Co., Ltd.) ;
  • Kim, Soyoung (Research & Development, Natural Choice Co., Ltd.) ;
  • Bang, Soonil (Research & Development, Natural Choice Co., Ltd.) ;
  • Kim, Dong Chung (Department of Human Nutrition and Food Science, Chungwoon University) ;
  • In, Man-Jin (Department of Human Nutrition and Food Science, Chungwoon University) ;
  • Chae, Hee Jeong (Research & Development, Natural Choice Co., Ltd.)
  • Received : 2014.06.09
  • Accepted : 2014.12.12
  • Published : 2014.12.30

Abstract

In vitro biological activities of Aloe vera gel and skin extracts were evaluated. Total polyphenol contents of Aloe vera skin were measured 41.12 mg/g. DPPH radical scavenging activity of Aloe vera skin-70% EtOH extract, Aloe vera skin-water extract, Aloe vera gel-70% EtOH extract and Aloe vera gel-water extract were 55%, 38%, 11% and 10%, respectively. In addition, 70% EtOH extract and water extract were compared with respect to SOD-like antioxidant activity of Aloe vera-70% EtOH extract has higher activity than Aloe vera water extract. Tyrosinase inhibition rate of Aloe vera gel extract was higher than Aloe vera skin extract. Alcohol dehydrogenase (ADH) and Acetaldehyde dehydrogenase (ALDH) relative percentage activity of Aloe vera gel extract were 126% and 216%, respectively. It was suggested that Aloe vera gel and skin extracts could be used as a functional biomaterial for functional food and cosmetics.

Keywords

References

  1. Vogler, B. K. and E. Erst (1999) Aloe vera: a systemic review of its clinical effectiveness. Br. J. Gen. Pract. 49: 823-828.
  2. Hu, Y., J. Xu, and Q. Hu (2003) Evaluation of antioxidant potential of Aloe vera (Aloe barbadensis miller) extracts. J. Agric. Food Chem. 51: 7788-7791. https://doi.org/10.1021/jf034255i
  3. Chitha, P., G. B. Sajithlal, and G. Chandrakasan (1998) Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Mol. Cell Biochem. 181: 71-76. https://doi.org/10.1023/A:1006813510959
  4. Rhim, J. Y., Y. S. Moon, S. H. Jung, K. Y. Lee, S. Y. Lyu, C. S. Shim, and W. B. Park (2002) Antimicrobial activities of combined extract of Aloe vera with propolis against oral pathogens. J. Korean Soc. Food Sci. Nutr. 31: 899-904. https://doi.org/10.3746/jkfn.2002.31.5.899
  5. Shin, Y. (1997) Studies on the chromones and anthraquinones in Aloe Barbadensis. Ph.D. Thesis. University of Seoul National, Seoul, Korea.
  6. Reynolds, T. (1985) The compounds in Aloe leaf exudates: a review. Bot. J. Linn. Soc. 90: 157-177. https://doi.org/10.1111/j.1095-8339.1985.tb00377.x
  7. Okamura, N., N. Hine, Y. Tateyama, M. Nakazawa, T. Fujioka, and A. Yagi (1997) Three chromones of Aloe vera leaves. Phytochem. 45: 1511-1513. https://doi.org/10.1016/S0031-9422(97)00148-9
  8. Reynolds, T. and A. Dweck (1997) Aloe vera leaf gel, a review update. J. Ethnopharmacol. 68: 3-37.
  9. Chang, K. W., J. S. Paek, G. C. Jang, and Y. G. Nam (1993) Fatty and organic acids, and barbaloin in various of Aloe species dried at different drying temperatures. J. Korean Agric. Chem. Soc. 36: 244-248.
  10. Yen, G. C., P. D. Duh, and D. Y. Chuang (2000) Antioxidant activity of anthraquinones and anthrone. Food Chem. 70: 437-441. https://doi.org/10.1016/S0308-8146(00)00108-4
  11. Jung, M. H. (1998) Usefulness old aloe food. Symposium on health foods 26: 15-25.
  12. Ro, J. Y., B. C. Lee, J. Y. Kim, Y. J. Chung, M. H. Chung, S. K. Lee, T. H. Jo, K. H. Kim and Y. I. Park (2000) Inhibitory mechanism of aloe aingle component (alprogen) on mediator relases in guinea pig lung mast cells activated with specific antigen-antibody reactions. J. Pharmcol. Exp. Ther. 292: 114-121.
  13. Thompson, J. E. (1991) Topical use of aloe vera derived allantoin gel in otolarymgology. Ear. Nose Throat. J. 70: 56-119.
  14. Folin, A. D. and W. Denis (1915) A colorimetric method for the determination of phenols (and phenol derivatives) in urine. J. Biochem. 22: 305-308.
  15. Heo, J. C., J. Y. Park, S. M. An, J. M. Lee, C. Y. Yun, H. M. Shin, T. K. Kwon, and S. H. Lee (2006) Anti-oxidant and anti-tumor activities of crude cxtracts by Gastrodia elata blume. Korean J. Food Prev. 13: 83-87.
  16. Lee, S. B., Y. K. Lee, and S. D. Kim (2006) Solubility, antioxidative and antimicrobial activity of chitosan-ascorbate. J. Med. Food 35: 973-978.
  17. Hong, E. S., G. W. Ahn, and B. K. Jo (2009) The study on the potential anti-aging properties of Prunella vulgaris extract in vitro and in vivo. J. Soc. Cos. Sci. Korean 34: 129-135.
  18. Marklund, S. and G. Marklund (1974) Involvement of the superoxide anion radical in the oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47: 469-474. https://doi.org/10.1111/j.1432-1033.1974.tb03714.x
  19. Lebsack, M. E., D. R. Peterson, and A. C. Collus (1977) Preferntial inhibition of the low $K_m$ aldehyde dehydrogenase activity by pargyline. Biochem. Pharmac. 25: 1151-1154.
  20. Tottmar, S. O., H. Petterson, and K. H. Kiessling (1973) The subcellular distribution and properties of aldehyde dehydrogenase in rat liver. Biochem. J. 135: 577-581. https://doi.org/10.1042/bj1350577a
  21. Jung, M. S., G. S. Lee, and H. J. Chae (2004) In vitro biological activity assay of ethanol extract of radish. J. Korean Soc. Appl. Biol. Chem. 47: 67-71.
  22. Lee, Y. C., K. H. Hwang, D. H. Han, and S. D. Kim (1997) Compositions of Opuntia ficus-indica. Korean J. Food Sci. Technol. 29: 847-853.
  23. Han, H. J., C. W. Park, C. H. Lee, and C. W. Yoo (2004) A study on anti-irritant effect od Aloe vera gel agrinst the irritation of sodium lauryl sulfate. Korean J. Dermatol. 42: 413-419.
  24. Kang, Y. H., Y. K. Park, and G. D. Lee (1996) The nitrite scavenging and electron donating ability of phenolic compounds. Korean J. Food Sci. Technol. 28: 624-630.
  25. Choe, J. H., A. R. Jang, B. D. Lee, X. D. Lie, H. P. Song, and C. H. Jo (2008) Antioxidant and antimicrobial effects of medicinal herb extract mix in pork patties during cold storage. Korean J. Food Sci. Ani. Resour. 28: 122-129. https://doi.org/10.5851/kosfa.2008.28.2.122
  26. Shin, E. H., S. J. Park, and S. K. Choi (2011) Component analysis and antioxidant activity of Opuntia ficus-indica var. saboten. J. East Asian Soc. Dietary Life 21: 691-697.
  27. Choi, W. (2008) A study on biological activities and anti-oxidative and-inflammatory effects of Aloe. MS Thesis. University of Konkuk, Seoul, Korea.
  28. Lim, J. A., Y. S. Na, and S. H. Beak (2004) Antioxidative activity and nitrite scavenging ability of ethanol extract from Phyllostachys bambusoides. Korean J. Food Sci. Technol. 36: 306-310.
  29. An, B. J., J. T. Lee, S. A. Lee, J. H. Kwak, J. M. Park, J. Y. Lee, and J. H. Son (2004) Antioxidant effects and application as natural ingredients of Korean Sanguisorbae L. J. Korean Soc. Appl. Biochem. 47: 244-250.
  30. Yang, H. J. and S. N. Park (2007) Component analysis and study on anti-clastase activity of Equlseham arverse extracts (II). J. Soc. Cosme. Sci. Korean 33: 1226-2587.
  31. Cho, J. J., K. K. Lee, B. K. Jo, and J. D. Choi (2000) Isolation and characterization of elastase inhibitor from Areca catechu. J. Soc. Cosme. Sci. Korean 35: 163-185.
  32. Sung, K. C. and K. J. Kim (2005) Tyrosinase activated inhibition effect and analysis of pine-needles extract. Korean Oil Chem. Soc. 22: 71-76.
  33. French, S. W. (1989) Biochemical basis for alcohol-induced liver injury. Clin. Biochem. 22: 41-49. https://doi.org/10.1016/S0009-9120(89)80067-0
  34. Cheong, J. C., J. Y. Lee, M. J. Kim, and J. H. Chung (1996) Effects of Aloe extract on ethanol metabolism. J. Fd. Hyg. Safety 11: 31-34.
  35. Sakai, K., Y. Sattoh, C. Ikawa, and T. Nishhata (1989) Effect of water extracts of aloe and some herbs in decreasing blood ethanol concentration in rats. Chem. Pharm. Bull. 37:155-159. https://doi.org/10.1248/cpb.37.155
  36. Franz, G., and M. Grun (1983) Chemistry, occurrence and biosynthesis of c-glycosyl compounds in plants. Planta Med. 47: 131-140. https://doi.org/10.1055/s-2007-969972

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