Korean Journal of Clinical Pharmacy (한국임상약학회지)

Korean College Of Clinical Pharmacy (한국임상약학회)
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Drug Prescribing Patterns for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease in Korea

우리나라에서의 천식 및 만성폐쇄성폐질환 치료제 처방 양상

  • Jang, Jin Kyung (Department of Pharmacy, St. Mary's Hospital, The Catholic University of Korea) ;
  • Kim, Hae Sook (Department of Pharmacy, Gangneung Asan Hospital) ;
  • Sohn, Hyun Soon (College of Pharmacy, Sookmyung Women's University) ;
  • Park, Chanmi (Review and Assessment Research Institute, Health Insurance Review and Assessment Services) ;
  • Kim, Ju Sang (Department of Internal Medicine, St. Mary's Hospital, The Catholic University of Korea) ;
  • Jung, Bock Hyun (Department of Internal Medicine, Gangneung Asan Hospital) ;
  • Ji, Eunhee (College of Pharmacy, Gachon University) ;
  • Cho, Jung Hwan (College of Pharmacy, Sookmyung Women's University) ;
  • Shin, Hyun Taek (College of Pharmacy, Sookmyung Women's University)
  • 장진경 (가톨릭대학교 인천성모병원 약제팀) ;
  • 김해숙 (강릉아산병원 약제팀) ;
  • 손현순 (숙명여자대학교 약학대학) ;
  • 박찬미 (건강보험심사평가원) ;
  • 김주상 (가톨릭대학교 인천성모병원 호흡기내과) ;
  • 정복현 (강릉아산병원 호흡기내과) ;
  • 지은희 (가천대학교 약학대학) ;
  • 조정환 (숙명여자대학교 약학대학) ;
  • 신현택 (숙명여자대학교 약학대학)
  • Received : 2014.02.07
  • Accepted : 2014.03.21
  • Published : 2014.03.31
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Abstract

Purpose: The aim of this study was to investigate drug prescription patterns for the treatment of asthma and chronic obstructive pulmonary disease (COPD) patients in Korea. Methods: Ambulatory adult patients who were diagnosed and received treatment for the asthma (ICD-10 code J45) or COPD (ICD-10 code J44) from January 2009 to September 2011 in two independent secondary hospitals in Korea were enrolled in this study. Prescribed drug lists were generated based on the evidence-based guidelines and prescribed drug dosage forms were identified from the patient medical records and computerized drug prescription databases of the study centers. Results: Total numbers of asthma and COPD patient enrolled in this study were 2,432 and 2,615, respectively. Individual prescription-based accumulated numbers of patient were 12,021 for asthma and 16,584 for COPD. The most commonly prescribed three drugs were oral predisolone, oral formoterol and oral montelukast for asthma and oral formoterol, oral doxofylline and inhaled tiotropium for COPD. Frequencies of oral drugs were 83.4% and 63.3% while inhalers were 16.4% and 30.2%, for asthma and COPD, respectively. Conclusion: The oral treatment was prescribed more in asthma and COPD patients than inhalers. To enhance the compliance of evidence-based guidelines for these chronic airway diseases, more realistic and specific strategies to increase the use of inhalers recommended as primary treatment options for asthma and COPD would be required.

Keywords

References

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