Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Nano-emulsion Formed with Phospholipid-Nonionic Surfactant Mixtures and its Stability

인지질-비이온계면활성제 혼합물로 형성된 나노에멀젼과 이의 안정성

  • Cho, Wan Goo (College of Medical Science, Jeonju University) ;
  • Kim, Eun Hee (College of Medical Science, Jeonju University)
  • 조완구 (전주대학교 의과학대학 기초의과학과) ;
  • 김은희 (전주대학교 의과학대학 기초의과학과)
  • Received : 2014.02.04
  • Accepted : 2014.02.20
  • Published : 2014.09.30
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Abstract

IIn this study, O/W type nano-emulsions were prepared by phospholipid-nonionic surfactant mixtures and octyldodecylmyristate using the phase transition low-energy emulsification method. The nano-emulsions were formed only in the very narrow area of the concentration of mixed surfactant and oil molar ratio of around 1 : 1. The particle size of the emulsions was decreased as adding the aqueous phase into the emulsions after phase inversion point unlike the emulsions formed only with nonionic surfactant. Nano-emulsion was stable at room temperature for more than a month. Thus, the nano-emulsions containing phospholipids can be widely used as a cosmetic formulations.

본 연구에서는 인지질-비이온계면활성제의 혼합계면활성제를 이용하여 옥틸도데실미리스테이트를 조성상전이 유화법으로 O/W 타입 나노에멀젼을 제조하였다. 혼합 계면활성제와 오일의 농도 비가 1 : 1 정도의 매우 좁은 영역에서 나노에멀젼이 형성되었다. 비이온계면활성제로만 제조된 나노에멀젼과는 달리 전상점 이후에 수용액상을 첨가함에 따라 에멀젼의 입자 크기가 감소하였다. 제조된 나노에멀젼은 실온에서 한 달 이상 안정하였다. 인지질을 함유하고 저에너지 유화법으로 제조된 나노에멀젼 제형은 화장품의 기재로서 널리 사용될 수 있다.

Keywords

References

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