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Trend Analysis of the Research on Bee Venom Acupuncture in South Korea, Based on Published Articles

  • Han, Chang Hyun (Department of Medical History & Literature Group, Korea Institute of Oriental Medicine) ;
  • Lee, Yong Seok (Department of Preventive Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Sung, Soo Hyun (Department of Medical History & Literature Group, Korea Institute of Oriental Medicine) ;
  • Lee, Bong Hyo (Department of Acupuncture, Moxibustion and Acupoint, College of Korean Medicine, Daegu Haany University) ;
  • Shin, Hwa Young (Department of Acupuncture, Moxibustion and Acupoint, College of Korean Medicine, Daegu Haany University) ;
  • Lee, Young Joon (Department of Preventive Medicine, College of Korean Medicine, Daegu Haany University)
  • Received : 2015.11.30
  • Accepted : 2015.12.30
  • Published : 2015.12.30

Abstract

Background: This study investigated current research trends in bee venom acupuncture in Korea. Materials and methods: The literature in Korea was reviewed using the search engines Science and Technology Society Village, Korean Studies Information Service System, National Discovery for Science Leaders, and Oriental Medicine Advanced Searching Integrated System. The keywords searched were "bee venom," "apitoxin," "apitherapy," and "bee sting." We selected 412 studies, which included Korean literary studies, experimental studies, and clinical studies. Results: We classified them by publication year, research type, disease and topic, and quality assessment. Among bee venom-related studies, clinical studies (235 studies) outnumbered experimental studies (149 studies) and literary studies (28 studies). Nineteen experimental studies concentrated on the theme of "anticancer." In the type analysis of clinical studies, lumbar disorders comprised 45 of 235 studies, followed by the effect on body. Forty-two randomized controlled trials (RCTs) have been published from 2003 to date (2015). Twenty-two studies used appropriate randomization methods. Fourteen studies had a Jadad score of 4-5 points; 15 studies, 1-3 points; and 13 studies, 0 points. Conclusions: Bee venom treatment is based on Korean traditional medicine theory. Numerous research studies suggest its effectiveness. Effort and academic approach on bee venom are expected to receive a positive evaluation.

Keywords

References

  1. Korean Pharmacopuncture Institute. Pharma-o-puncturology. Korean Pharmacopuncture Institute, editor. Seoul:Elsevier Korea. 2008.
  2. Korean Pharmacopuncture Institute. Pharmacopuncture Procedure Guide. Korean Pharmacopuncture Institute, editor. Seoul:Korean Pharmacopuncture Institute. 2008.
  3. Korean Pharmacopuncture Institute. Pharmacopuncturology. Korean Pharmacopuncture Institute, editor. Seoul:Elsevier Korea. 2011.
  4. White AR, Ernst E. A systematic review of randomized controlled trials of acupuncture for neck pain. Rheumatology (Oxford, England). 1999;38(2):143-147. PubMed PMID: 10342627. Epub 1999/05/26. eng. https://doi.org/10.1093/rheumatology/38.2.143
  5. Koh H. Experimental studies on the effect of bee venom therapy on the analgesic, anti-pyretic and anti-inflammatory action. Korean Orien Med. 1976;13(1):283-292.
  6. Lee YC, Nam DJ, Huh G, Lee JE, Kim BNR, Song EM, et al. The comparative study on the effect of hwangryunhaedoktang pharmacopuncture and essential bee venom pharmacopuncture for cervical pain caused by traffic accidents. J Orien Rehabil Med. 2014;24(4):145-153.
  7. Im SH, Lee MJ, Lee SM, Kim ES, Lee SH, Kang JW, et al. A comparative study of the effects of jungsongouhyul pharmacopuncture treatment and bee venom pharmacopuncture treatment on peripheral facial paralysis. Journal of Korean Acupuncture & Moxibustion Society. 2014;31(2):135-144.
  8. Kim JH, Jeong JY, Yee SW, Shin SY, Park JH, Kim CH, et al. Comparison of the efficacy between needle-embedding therapy and sweet bee venom pharmacopuncture therapy on peripheral facial paralysis. Journal of Korean Acupuncture & Moxibustion Society. 2013;30(4):35-44. Korean.
  9. Ro HR, Park SH, Lee JY, Choo WJ, Han SW, Kim SW, et al. The comparative study on the effect of ShinBaro pharmacopuncture treatment and bee venom pharmacopuncture treatment of patient with spondylolisthesis. J Korea CHUNA Med Spine & Nerves. 2012;7(2):53-61.
  10. Cho SH, Cho HS, Lee KY, Yun SH, Jung WS, Kim SH. The comparative study of effectiveness of cotreatment with samgieum-gagam, acupuncture and sweet bee venom acupuncture on post-stroke shoulder pain. Journal of Korean Acupuncture & Moxibustion Society. 2012; 29(2):15-27.
  11. Lee JH, Kim JS, Yang KY, Han SY, Lee JY, Hwang EM. Effect of bee-venom acupuncture on low back pain by traffic accidents. J Korea CHUNA Med Spine & Nerves. 2011;6(2):61-70.
  12. Park JA, Lee CH, Kwon GS, Lee KA, Jang KJ. The effects of sweet bee venom pharmacopuncture on the post-stroke hemiplegic shoulder pain. Journal of Korean Acupuncture & Moxibustion Society. 2011;28(4):37-47.
  13. Ku JY, Lee KH, Cho SW, Lee SC, Youn HM, Jang KJ, et al. Comparison of the effects between sweet bee venom pharmacopuncture and scolopendrid pharmacopuncture on carpal tunnel syndrome. Pharmacopuncture. 2010;13(4):75-89.
  14. Park JH, Jang SH, Lee CH, Ku JY, Jeun DS, Ahn CB, et al. The clinical research of the effectiveness of pharmacopuncture complex therapy on peripheral facial paralysis. Journal of Korean Acupuncture & Moxibustion Society. 2010;27(2):79-87.
  15. Noh JH, Park JA, Cho SW, Youn HM, Jang KJ, Song CH, et al. Effect of bee-venom acupuncture on upper limb spasticity of stroke patients. Journal of Korean Acupuncture & Moxibustion Society. 2010;27(4):115-125.
  16. Choi JY, Lee H, Kang JH, Kim YI, Kim JH, Lee SH, et al. Comparative study of general oriental medical treatment and bee venom pharmacopuncture on acute peripheral facial paralysis patient with postauricular pain. Journal of Korean Acupuncture & Moxibustion Society. 2009;26(5):95-103.
  17. Gwak JY, Cho SY, Shin AS, Lee IW, Kim NH, Kim HM, et al. Efficacy of bee-venom acupuncture on central post stroke pain - single-blind randomized controlled trial. Journal of Korean Acupuncture & Moxibustion Society. 2009;26(6):205-214.
  18. Kang I, Moon JY, Lim MJ, Cho JH, Lee HE. The comparison study between different interventions for treating acute ankle sprain - using dry needle, bee venom acupuncture, hwangryunhaedoktang herbal acupuncture. Journal of Korean Acupuncture & Moxibustion Society. 2008;25(5):89-95.
  19. Kim HB, Lee RM, Lee MH, Choi YS, Kim JI, Lee YH, et al. Comparative Study of Effects of ‘Intramuscular Bee Venom Herbal Acupuncture' and ‘Intracutaneous Bee Venom Herbal Acupuncture' in Knee Osteoarthritis Patients. Journal of Korean Acupuncture & Moxibustion Society. 2008;25(2):151-164.
  20. Yang KR, Song HS. A comparative study of warm needling and bee venom pharmacopuncture on osteoarthritis of the knee - a randomized controlled trial. Pharmacopuncture. 2008;11(2):21-31.
  21. Kim SC, Na WM, Lee SY, Jang EH, Lim SI. A study on pain relief effects and allergic responses for the osteoarthritis of the knee joint between sweet bee venom and bee venom pharmacopuncture. Pharmacopuncture. 2008;11(1):31-40. https://doi.org/10.3831/KPI.2008.11.1.031
  22. Kim JH, Jang SH, Yoon HM, Jang KJ, Ahn CB, Kim CH, et al. The comparison of effectiveness between bee venom and sweet bee venom therapy on chronic lower back pain. Pharmacopuncture. 2008;11(4):15-24. https://doi.org/10.3831/KPI.2008.11.4.015
  23. Yook TH, Yu JS, Jung HS. Effects of sweet bee venom and bee venom on the heart rate variability. Pharmacopuncture. 2008;11(1):41-54.
  24. Lee KH, Youn HM, Ko WS, Song CH, Jang KJ, Ahn CB, et al. Comparison of treatment effects and allergic responses to stiff neck between sweet bee venom and bee venom pharmacopuncture. Pharmacopuncture. 2008;11(4):39-48. https://doi.org/10.3831/KPI.2008.11.4.039
  25. Yoo HS, Kim JS. The effect of sweet bee venom pharmacopuncture (SBVP) on cancer -related pain: a randomized controlled trial and double Blinded. Pharmacopuncture. 2008;11(1):21-29.
  26. Lee SH, Kang MW, Lee H, Lee SY. Effectiveness of bee-venom acpuncture and ouhyul herbal acpuncture in herniation of nucleus pulposus-comparison with acpuncture therapy only. Journal of Korean Acupuncture & Moxibustion Society. 2007;24(5):197-205.
  27. Na WM, Lee SY, Jang EH, Kim SC, Moon HC, Kim SM, et al. A study on pain relief effects and allergic responses for the osteoarthritis of the knee joint between sweet bee venom and bee venom pharmacopuncture. Pharmacopuncture. 2007;10(2):47-55.
  28. Lee TH, Hwang HS, Chang SY, Cha JH, Jung KH, Lee EY, et al. The comparison of effectiveness between bee venom and sweet bee venom therapy on low back pain with radiating pain. Pharmacopuncture. 2007;10(3):85-89.
  29. Ko CN, Min IK, Park SW, Jung WS, Moon SK, Park JM, et al. Effectiveness of bee venom acupuncture on shoulder pain after stroke. The Journal of Korean Oriental Medicine. 2007;28(1):11-24.
  30. Song BY. A clinical study on the effects of sweet bee venom herbal acupuncture for patients with whiplash injury. Pharmacopuncture. 2007;10(3):77-83. https://doi.org/10.3831/KPI.2007.10.3.077
  31. Seo JW, Park MJ, Sung IH, Kim NO, Ahn CK. A clinical study of bee venom acupuncture therapy on the treatment of acute ankle sprain. Journal of Korean Acupuncture & Moxibustion Society. 2006;23(1):95-103.
  32. An BJ, Song HS. Effect of bee venom -acupuncture therapy on patients with sprain of the wrist joint. Pharmacopuncture. 2006;9(2):167-171. https://doi.org/10.3831/KPI.2006.9.2.167
  33. An BJ, Kim KT, Kang MS, Song HS. Effect of bee venom-acupuncture on patients with osteoarthritis of knee joint. Journal of Korean Acupuncture & Moxibustion Society. 2006;23(4):15-20.
  34. Eom JY, Won SH, Kwon KR, Lee HS. Comparative study of acupuncture, bee venom acupuncture and bee venom herbal acupuncture on the treatment of post-stroke hemiplegic shoulder pain. Pharmacopuncture. 2006;9(1):139-154.
  35. Lee DY, Lee GM, Yeom SC, Kim DH, Kim DJ. A clinical study of bee venom acupuncture therapy on shoulder pain patients in stroke sequelae. Journal of Korean Acupuncture & Moxibustion Society. 2006;23(4):69-80. Korean.
  36. Lee JS, Lee JY, Kwon KR, Lee HC. A study on allergic responses between bee venom and sweet bee venom pharmacopuncture. Pharmacopuncture. 2006;9(3):61-77. https://doi.org/10.3831/KPI.2006.9.3.061
  37. Cho SW, Go KH, Nam JH, Kim MS, Lee SY, Lee IS, et al. The effectiveness of zingiberis rhizoma herbal acupuncture therapy and bee venom herbal acupuncture therapy on the poststroke hemiplegic shoulder pain. J Orien Rehabil Med. 2005;15(4):77-87. Korean.
  38. Kim KT, Song HS. A randomized controlled double blinding study of bee venom acupuncture therapy on sprain of c-spine. Journal of Korean Acupuncture & Moxibustion Society. 2005;22(4):189-195.
  39. Kim KT, Song HS. The effectiveness of bee venom acupuncture therapy on the treatment of sprain of l-spine (a randomized controlled trial; double blinding). Journal of Korean Acupuncture & Moxibustion Society. 2005;22(4):113-120.
  40. Song HS. The effect of bee venom acupuncture (BVA) on acute ankle sprain: a randomized controlled trial and double blinding - pilot study. Pharmacopuncture. 2005;8(2):11-16.
  41. Kim MS, Kim HJ, Park YJ, Kim EH, Lee EY. The clinical research of the efficacy of bee venom aqua-acupuncture on peripheral facial paralysis. Journal of Korean Acupuncture & Moxibustion Society. 2004;21(4):251-262. Korean.
  42. Ryu SM, Lee JS, Kim SS, Jung SH. The effect of intra-articular bee venom injection on osteoarthritis of the knee. J Orien Rehabil Med. 2004;14(1):35-52.
  43. An GH, Lee H, Lee BR. The comparative study on the bee-venom therapy and common acupuncture therapy for the lateral epicondylitis (tennis elbow). J Korean Orien Med. 2004;13(2):267-276.
  44. Lee H. The comparative study on the bee-venom therapy and common acupuncture therapy for the acute ankle sprain. Korean J Acupunct. 2004;21(4):133-143.
  45. Lee SN, Hong SY, Jo HC, Byeon IJ, Song HS, Kim GH. The clinical study on bee venom acupuncture treatment on osteoarthritis of knee joint. Journal of Korean Acupuncture & Moxibustion Society. 2003;20(5):73-81. Korean.
  46. Chung WS, Lee JS, Chung SH, Kim SS. The effect of bee venom acupuncture on patient with herniation of nucleus pulposus of lumbar spine. J Orien Rehabil Med. 2003;13(2):87-101. Korean.
  47. Lee SH, Hong SJ, Kim SY, Yang HI, Lee JD, Choe DY, et al. Randomized controlled double blind study of bee venom therapy on rheumatoid arthritis. Journal of Korean Acupuncture & Moxibustion Society. 2003;20(6):80-88. Korean.
  48. Kim MH. Bee Venom Therapy and Bee Acupuncture Therapy. Kim MH, editor. Seoul: Korean Education Plan. 1994.
  49. Habermann E. Chemistry, Pharmacology and Toxicology of Bee, Wasp and Hornet Venoms. In: Bucherl W, Buckley EE, editors. Venomous Animals and Their Venoms: Venomous Invertebrates. New York: Academic Press. 1971:61-93.
  50. Lee JA, Son MJ, Choi J, Jun JH, Kim JI, Lee MS. Bee venom acupuncture for rheumatoid arthritis: a systematic review of randomised clinical trials. BMJ open. 2014;4(11):e006140. PubMed PMID: 25380812. Pubmed Central PMCID: 4225238. Epub 2014/11/09. eng. https://doi.org/10.1136/bmjopen-2014-006140
  51. Kweon KL, Koh HK, Kim CH. Experimental studies on the effect of api-toxin therapy on the anti-inflammatory action. Kyunghee Univ Oriental Med J. 1993;16:297-323.
  52. Begg C, Cho M, Eastwood S, Horton R, Moher D, Olkin I, et al. Improving the quality of reporting of randomized controlled trials. The CONSORT statement. Jama. 1996 Aug 28;276(8):637-639. PubMed PMID: 8773637. Epub 1996/08/28. eng. https://doi.org/10.1001/jama.1996.03540080059030
  53. Chalmers I. Current Controlled Trials: an opportunity to help improve the quality of clinical research. Current controlled trials in cardiovascular medicine. 2000;1(1):3-8. PubMed PMID: 11714397. Pubmed Central PMCID: 59587. Epub 2001/11/21. Eng. https://doi.org/10.1186/CVM-1-1-003
  54. MacPherson H, White A, Cummings M, Jobst KA, Rose K, Niemtzow RC, et al. Standards for Reporting Interventions in Controlled Trials of Acupuncture: the STRICTA recommendations. Journal of alternative and complementary medicine (New York, NY). 2002 Feb;8(1):85-89. PubMed PMID: 11890439. Epub 2002/03/14. eng. https://doi.org/10.1089/107555302753507212
  55. Kim WY, Lee SD, Lim BM, Kim KS. The assessment of appropriateness of acupuncture methodology based on STRICTA recommendations-the discussion of 5 systematic reviews and their objects 58 randomized controlled trials using the new tools. Journal of Korean Acupuncture & Moxibustion Society. 2007;24(5):151-170.

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