Journal of Korean Traditional Oncology (대한암한의학회지)

Korean Association of Traditional Oncology (대한암한의학회)
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A case report of a clinically diagnosed advanced lung cancer patient after treatment with Gunchilgyebok-Jung

건칠계복정으로 치료한 임상적 진행성 폐암 환자 1례

  • Park, So jung (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University) ;
  • Kang, Hwi joong (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University) ;
  • Park, Ji hye (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University) ;
  • Cho, Chong kwan (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University) ;
  • Yoo, Hwa seung (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
  • 박소정 (대전대학교 둔산한방병원 동서암센터) ;
  • 강휘중 (대전대학교 둔산한방병원 동서암센터) ;
  • 박지혜 (대전대학교 둔산한방병원 동서암센터) ;
  • 조종관 (대전대학교 둔산한방병원 동서암센터) ;
  • 유화승 (대전대학교 둔산한방병원 동서암센터)
  • Received : 2015.03.28
  • Accepted : 2015.04.20
  • Published : 2015.04.25
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Abstract

Objective : This case report presents the effects of Gunchilgyebok-Jung to a patient who was clinically diagnosed with advanced lung cancer. Methods : The study involved a 74-year-old male patient clinically diagnosed with advanced (stage III) lung cancer by chest computed tomography (CT) and positron emission tomography. The patient had two masses (11.32 mm and $23.03mm{\times}35.34mm$) in the right upper lobe of the lung and in the mediastinum respectively. Gunchilgyebok-Jung commonly used for its anti-tumor and anti-inflammatory effect is composed of Rhus verniciflua stokes and Guizhifuling wan extracts. We prescribed Gunchilgyebok-Jung at a dosage of 1 g three times a day for 50 days. Results : After the administration of Gunchilgyebok-Jung, a decrease in tumor size to 10.69 mm and $22.71mm{\times}34.21mm$ on chest CT was observed. A numerical rating scale (NRS) showed an improvement in symptoms from points 7-8 to 3-4. Conclusion : This study suggests that Gunchilgyebok-Jung may have considerable anti-tumor and immunopotentiating activity in lung cancer without any adverse effects.

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References

  1. 보건복지부 암등록통계(국가승인통계 11744호), 2013
  2. 대한병리학회. 병리학. 서울: 고문사;989-9992,2002
  3. 박재현, 엄석기, 정현식, 김경석, 윤성우, 최원철. 積聚를 위주로 한 종양의 병인병기에 관한 소고. 대한암한의학회지 12(1):1-13, 2007
  4. 박재현, 문구. 積聚를 위주로 한 종양의 치법에 관한 소고. 대한암한의학회지 13(1):1-11, 2008
  5. 송미선, 김윤상, 임은미. 건칠에 대한 문헌적 고찰. 대한한방부인과회지 15(1):60-76, 2002
  6. 윤성우,박재우,김경식,정현식,최원철. 건칠추출물(Nexia)의 독성 실험과 급성 림프구성 백혈병환자의 임상증례군 보고. 대한암한의학회지 11(1):1-21, 2006
  7. 김은희, 박소정, 최원철, 이수경. 알러젠제거 옻나무 추출물 투여로 생존기간이 연장된 편평세포폐암 환자 1례. 대한암한의학회지 16(2):35-41, 2011
  8. 김보근, 박상채. 옻나무 전탕추출물 치료 를 받은 위암 4기 환자 1례. 대한암한의학회지 18(1):17-22, 2013
  9. 권은미,이수경,이상헌,김경석,윤성우,최원철, 한종현,정현식. 알러젠 제거 옻나무 추출 물 위주의 한방치료로 관리한 저등급 자궁내막 간질육종 증례보고. 대한암한의학회지 16(2):1-8, 2011
  10. 김보근, 박상채. 옻나무 전탕추출물 한방치료와 항암화학요법을 병용한 대장암 4기 환자 2례. 대한암한의학회지 16(2):63-70, 2011
  11. 남은정, 이연경, 이동녕, 김형준. 계지복령환 제제의 원발성 월경통에 대한 임상적 효과. 동의생리병리학회지 20(5):1364-1368, 2006
  12. Takao Namiki, Hiromi Sato, Yukari Matsumoto, Haruka Kakikura, Koichi Ueno, Atsushi Chino, Hideki Okamoto, Akito Hisanaga, Akiyo Kaneko, Toshiaki Kita, Maki Kihara, Makio Shozu, and Katsutoshi Terasawa. Identification of a Predictive Biomarker for the Beneficial Effect of Keishibukuryogan, a Kampo (Japanese Traditional) Medicine, on Patients with Climacteric Syndrome. Evidence-Based Complementary and Alternative Medicine 2014:1-8, 2014
  13. 서창섭, 김온순, 신현규. LC-MS/MS를 이용한 계지복령환의 동시분석 및 항산화 효능 연구. 생약학회지 45(3):240-248, 2014
  14. 이수경. Effect of the geijibokryunghwan on human hepatocarcinoma cells. 대한동의생리병리학회 17(2):568-573, 2003
  15. 황덕상, 조정훈, 장준복, 이경섭. 계지복령환의 Hela cell 증식억제와 사멸효과. 대한한의학회지 27(1):23-35, 2006
  16. Yao Zhang, Shulan Zhang. Inhibition effect of Guizhi-Fuling-decoction on the invasion of human cervical cancer. Journal of Ethnopharmacology 120(1):25-35, 2008 https://doi.org/10.1016/j.jep.2008.07.044
  17. Kim JH, Shin YC, Ko SG. Integrating Traditional Medicine into Modern Inflammatory Disease Care: Multitargeting by Rhus verniciflua Stokes. Mediators of Inflammation 2014:1-17, 2014
  18. Lee JO, Moon JW. Lee SK. Kim SM, Kim N, Ko SG, Kim HS, Park SH. Rhus verniciflua Extract Modulates Survival of MCF-7 Breast Cancer Cells through the Modulation of AMPK-Pathway. Biol. Pharm. Bull. 37(5):794-801, 2014 https://doi.org/10.1248/bpb.b13-00893
  19. 김성학, 김경준. 건칠이 혈관신생관련 단백질 발현에 미치는 영향. 한방안이비인후피부과학회지 19(3):1-12, 2006

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