Preventive Nutrition and Food Science

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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A Novel Lactobacillus casei LP1 Producing 1,4-Dihydroxy-2-Naphthoic Acid, a Bifidogenic Growth Stimulator

  • Kang, Jo-Eun (Department of Biotechnology, Korea National University of Transportation) ;
  • Kim, Tae-Jung (Department of Biotechnology, Korea National University of Transportation) ;
  • Moon, Gi-Seong (Department of Biotechnology, Korea National University of Transportation)
  • Received : 2014.11.27
  • Accepted : 2015.03.03
  • Published : 2015.03.31
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Abstract

1,4-Dihydroxy-2-naphthoic acid (DHNA) is a bifidogenic growth stimulator (BGS) and could be a functional food ingredient since bifidobacteria are beneficial for human health. For that reason, lactic acid bacteria producing DHNA have been screened. A lactic acid bacterium LP1 strain isolated from a natural cheese was confirmed to produce DHNA, analyzed by a HPLC method. The strain was identified as Lactobacillus casei by 16S rRNA gene sequence analysis. The cell-free supernatant of fermented whey produced by L. casei LP1 presented the BGS activity for three bifidobacterial strains such as Bifidobacterium longum subsp. infantis KCTC 3127, Bifidobacterium bifidum KCTC 3202, and Bifidobacterium breve KCTC 3220 which were human-originated. To the best of our knowledge, a L. casei strain which can produce DHNA was firstly identified in this study.

Keywords

References

  1. Isawa K, Hojo K, Yoda N, Kamiyama T, Makino S, Saito M, Sugano H, Mizoguchi C, Kurama S, Shibasaki M, Endo N, Sato Y. 2002. Isolation and identification of a new bifidogenic growth stimulator produced by Propionibacterium freudenreichii ET-3. Biosci Biotechnol Biochem 66: 679-681. https://doi.org/10.1271/bbb.66.679
  2. Sanders ME, Lenoir-Wijnkoop I, Salminen S, Merenstein DJ, Gibson GR, Petschow BW, Nieuwdorp M, Tancredi DJ, Cifelli CJ, Jacques P, Pot B. 2014. Probiotics and prebiotics: prospects for public health and nutritional recommendations. Ann NY Acad Sci 1309: 19-29. https://doi.org/10.1111/nyas.12377
  3. Okada Y, Tsuzuki Y, Miyazaki J, Matsuzaki K, Hokari R, Komoto S, Kato S, Kawaguchi A, Nagao S, Itoh K, Watanabe T, Miura S. 2006. Propionibacterium freudenreichii component 1,4-dihydroxy-2-naphthoic acid (DHNA) attenuates dextran sodium sulphate induced colitis by modulation of bacterial flora and lymphocyte homing. Gut 55: 681-688. https://doi.org/10.1136/gut.2005.070490
  4. Okada Y, Tsuzuki Y, Narimatsu K, Sato H, Ueda T, Hozumi H, Sato S, Hokari R, Kurihara C, Komoto S, Watanabe C, Tomita K, Kawaguchi A, Nagao S, Miura S. 2013. 1,4- Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii reduces inflammation in interleukin-10-deficient mice with colitis by suppressing macrophage-derived proinflammatory cytokines. J Leukoc Biol 94: 473-480. https://doi.org/10.1189/jlb.0212104
  5. Bentley R, Meganathan R. 1982. Biosynthesis of vitamin K (menaquinone) in bacteria. Microbiol Rev 46: 241-280.
  6. Myers CR, Myers JM. 1993. Role of menaquinone in the reduction of fumarate, nitrate, iron(III) and manganese(IV) by Shewanella putrefaciens MR-1. FEMS Microbiol Lett 114: 215-222. https://doi.org/10.1111/j.1574-6968.1993.tb06576.x
  7. Newman DK, Kolter R. 2000. A role for excreted quinones in extracellular electron transfer. Nature 405: 94-97. https://doi.org/10.1038/35011098
  8. Saffarini DA, Blumerman SL, Mansoorabadi KJ. 2002. Role of menaquinone in Fe(III) reduction by membrane fraction of Shewanella putrefaciens. J Bacteriol 184: 846-848. https://doi.org/10.1128/JB.184.3.846-848.2002
  9. Rohmer M, Knani M, Simonin P, Sutter B, Sahm H. 1993. Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. Biochem J 295: 517-524. https://doi.org/10.1042/bj2950517
  10. Rohmer M, Seemann M, Horbach S, Bringer-Meyer S, Sahm H. 1996. Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis. J Am Chem Soc 118: 2564-2566. https://doi.org/10.1021/ja9538344
  11. Schwender J, Seemann M, Lichtenthaler HK, Rohmer M. 1996. Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus. Biochem J 316: 73-80. https://doi.org/10.1042/bj3160073
  12. Tojo R, Suarez A, Clemente MG, de los Reyes-Gavilan CG, Margolles A, Gueimonde M, Ruas-Madiedo P. 2014. Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis. World J Gastroenterol 20: 15163-15176. https://doi.org/10.3748/wjg.v20.i41.15163
  13. Plaza-Diaz J, Gomez-Llorente C, Fontana L, Gil A. 2014. Modulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the gut and in the liver by probiotics. World J Gastroenterol 20: 15632-15649. https://doi.org/10.3748/wjg.v20.i42.15632
  14. Furuichi K, Katakura Y, Ninomiya K, Shioya S. 2007. Enhancement of 1,4-dihydroxy-2-naphthoic acid production by Propionibacterium freudenreichii ET-3 fed-batch culture. Appl Environ Microbiol 73: 3137-3143. https://doi.org/10.1128/AEM.01307-06

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