Journal of Digital Convergence (디지털융복합연구)

The Society of Digital Policy and Management (한국디지털정책학회)
권호 표지
DOI QR코드

DOI QR Code

The Effect of 12-Weeks Combined Training and Policosanol Supplimentation Inflammatory and Maker and Leptin in Obese Women

12주간 복합운동 및 Policosanol 섭취가 비만 중년여성의 염증표지인자 및 렙틴에 미치는 효과

  • Received : 2015.01.28
  • Accepted : 2015.04.20
  • Published : 2015.04.28
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study is investigating the effects of combination of policosanol intake and combined exercise to the defence mechanism and the changes of fat cell control hormones by analyzing the changes of inflammatory markers LDH and CPK, and Leptin when having policosanol intake and combined exercise together against obese women for 12 week. These groups are randomly assigned to the control group, policosanol intake group, combined exercise group and combined treatment group with 12 obese women in esch group and they performed muscular resistance exercise and an aerobic exercise which was walking twice a week. After 12 weeks the LDH showed significant differences(p<.01) at exercise period, and also showed the significant differences(p<.05) in the effect of the interaction between exercise period and group. The changes in Leptin showed significant differences(p<.001) at exercise period. In summary, carrying out together of the aerobic exercise, muscular resistance exercise or policosanol intake can be considered to have the beneficial effects to prevent various disease which caused by inflammatory maker and Leptin and it also increases its effects.

본 연구는 12주간 비만 여성을 대상으로 규칙적인 복합운동과 policosanol 섭취 병행이 염증표지인자 LDH와 CPK, Leptin에 미치는 변화를 분석함으로써 복합운동과 policosanol 섭취 병행이 생체 방어반응과 지방세포 조절 호르몬 변화에 미치는 영향을 규명하는데 있다. 통제집단 12명, policosanol 섭취집단 12명, 복합운동집단 12명, 복합 처치 집단 12명으로 무선 배정하였고 주 2회는 근저항성 운동, 주2회는 걷기형태의 유산소운동을 실시하였다. 12주 후 LDH는 운동시기에서 유의한 차이를 보였고(p<.01), 운동시기와 그룹간의 상호작용 효과에서도 유의한 차이 (p<.05)를 나타냈다. 또한 leptin의 변화에서는 운동시기에 유의한 차이(p<.001)를 나타내었다. 이상의 결과를 종합하면 복합 운동이나, policosanol 섭취는 염증표지인자와 렙틴에 긍정적인 영향을 미치며, 복합운동과 policosanol 섭취의 병행은 그 효과를 더욱 증대시키는 것으로 사료된다.

Keywords

References

  1. Chang Kew Kim, Bong Joo Sung(1999). The effects of aerobic exercise on the surum leptin in young obese subjects. Journal of sports science research, 18, 61-71.
  2. Hyo Jeong Kim, Chang Keun Kim(2005). Effects of one year exercise training program on the impaired fasting glucose, cardiovascular risk factors and aerobic exercise capacity in middle aged men. Exercise Science, 14(2), 203-213.
  3. Yong Su Baek(2007). Function roles of leptin in the autonomic neurons innervating the urogenital system. Medicine and Science in Sports and Exercise. 20(3). 249-254. https://doi.org/10.1249/00005768-198806000-00006
  4. Byung Kang You(2005). The change of severely obese middle aged women's body fat, cardiovascular strength and blood hormone on the combined exercise. Journal of exercise nutrition & biochemistry, 9(3), 253-259.
  5. Ji Seon Jang, Chang Bae Hong, Ji Eun Lee, Hong Soo Kim, Ju Sik Park, Ki Jin Kim(2006). Effects of 12 weeks combined exercise program on body composition and atherosclerosis indices in middle-aged diabetic and obese women. Exercise Science, 15(1), 105-116.
  6. ACSM(2000). ACSM's guidelines for exercise testing and prescription(6th). Baltimore American College of Sports Medicine.
  7. Bluher S, Mantzoros CS(2004). The role of leptin in regulating neuroendocrine function in humans. J Nur. sep;124(9), 2469S-2474S.
  8. Costill, D. D., Allen, M. G., Kirwan, J.A., Mitchell, J.B., Thomas, R. & Park, S.H.(1988). Effects of repeated days of intensified training on muscular glycogen and swimming performance. Medicine and Science in Sports and Exercise. 20(3). 249-254. https://doi.org/10.1249/00005768-198806000-00006
  9. Gollnick, P.D. & Elliot, D.L.(1986). Enzymatic adaptation and significance for metabolic response to exercise. Biochemistry Exercise International Series on sports science. 16. 196-197.
  10. Hansen, K. N., Bierre-Kundsen. J., Brodthagen. U., Jordal. R., & Paulev. P. E.(1982). Muscle cell leakage long distance training. Journal of Applied physiology, 40. 868-972.
  11. Janssen, G. M. E., Kuipers, H., Willems, G.M., Does RIMM., Janssen MPE., Geurten, P.(1989). Plasma activity of muscle enzyme : quantification of skeletal muscle damage and relationship with metabolic variables. International Journal Sports Medicine, 10(3), 128-131.
  12. Karlsson, J., Sjodin. B., Thorstensson A., Hulten B., & Fr ith K.(1975). LDH isoenzymes in skeletal muscles of endurance and strength trained athletes. Acta Physiological Scandinavia, 93, 150-156. https://doi.org/10.1111/j.1748-1716.1975.tb05803.x
  13. Lehniger, A. L.(1982). Principles of Biochemisty. New York: Worth Publishers.
  14. Menendez R, Amor A, Rodeiro I, et al(2001). Policosnol modulates HMG Co A reductase activity in cultured fibroblasts. Arch Med Res.
  15. Noakes, T. D(1997). Effects of exercise on serum enzyme activities in human. International Journal of Sports Medicine, 4, 245-267.
  16. Ryan, A. S., Prately, R. E., & Elahi, D.(2000). Changes in plasma leptin and insulin actin with resistance training in postmenopausal women. Int. J. obese Metab., 24(1), 27-32. https://doi.org/10.1038/sj.ijo.0801080
  17. Schwarz. L., & Kindermann, W. A.(1996). Beta-endorphin, catecholamines, and cortisol during exhaustive endurance exercise. Internal Journal of Sports Medicine. 10, 324-328.
  18. Singh DK, Li L, Porter TD(2006). Policosnol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinases. J Pharmacol Exp Ther. 106, 107-144.
  19. Shodin B., Thorsternsson A., K. and LDH isoenzyme pattern in human skeletal muscle. Acta Physical Scandinvia. 97, 150-157. https://doi.org/10.1111/j.1748-1716.1976.tb10247.x
  20. Weltman J. Y., Wideman, L., Hartman, M. L., Veldhuis, J. D., & Weltman, A.(2001).Growh hormone release during acute and chronic aerobic and resistance exercise: recent findings. Sports Med, 32(15), 987-1004.
  21. Zhang Y, Proenca R, et al.,(1994). Positional cloning of the mouse obese gene and its human homologue. Nature, 372, 425-432. https://doi.org/10.1038/372425a0