DOI QR코드

DOI QR Code

A Case Report on Two Psoriasis Patients with Insomnia

불면증상을 동반한 건선 환자 치험 2례

  • Lee, Ki Hoon (Gangnam Dongyak Korean Medical Clinic) ;
  • Yang, Ji Eun (Gangnam Dongyak Korean Medical Clinic) ;
  • Chang, Gyu Tae (Department of Pediatrics, College of Korean Medicine, Kyung Hee University)
  • Received : 2015.01.22
  • Accepted : 2015.03.17
  • Published : 2015.03.31

Abstract

Objectives: The purpose of this study is to present two treatment cases of psoriasis with insomnia. Methods: We administered Guibi-tang medication to the psoriasis patients with insomnia and tested the results by Psoriasis Area and Severity Index(PASI) and Insomnia Severity Index(ISI) as well. Results: After the treatment both the patients showed improvements in PASI and ISI as well. PASI of Patient 1 changed from 15.2 to 1.2 along with the change of ISI from 27 to 2. In case of Patient 2, PASI changed from 14.6 to 1.8 while ISI changed from 21 to 6. Conclusions: The results suggest that Guibi-tang can be an effective treatment for insomnia and psoriasis as well. Further studies will be needed to demonstrate conclusively the effect of Guibi-tang on psoriasis cure.

불면을 동반한 건선(乾癬) 환자(患者)에게 불면과 건선(乾癬)의 경중이 비례하는 양상을 보인 환자(患者)에게 불면을 치료(治療)하면 건선(乾癬)이 회복될 것으로 판단되었다. 이와 관련하여 심혈부족(心血不足)이 불면의 원인(原因)이라고 판단되는 건선(乾癬) 환자(患者)에게 귀비탕(歸脾湯)을 투약해서 불면과 건선(乾癬)이 동시에 회복되는 결과(結果)를 확인했다. 아직 명확한 건선(乾癬) 치료(治療) 지침이 확립되지 않은 상황에서 건선(乾癬) 자체를 보고 접근해야 하는 경우도 있지만 건선(乾癬)과 동반된 기저 질환이 건선(乾癬)의 경중과 비례한다면 동반된 질환을 치료(治療)해서 건선(乾癬)을 치료(治療)할 수 있다는 가능성을 얻었다. 앞으로 건선(乾癬) 환자(患者)가 다른 기저 질환을 동반하고 이러한 질환의 경중이 건선(乾癬)과 비례한다면 이 질환의 치료(治療)를 시도하는 것이 건선(乾癬)의 회복에 도움을 줄 수 있을 것으로 보인다.

Keywords

References

  1. Andrew Warin. Psoriasis. Seoul:Academia. 2005: 7-8, 102.
  2. Kim SC, Ahn KJ, Hann SK, Kim JW, Sung KJ, Kye YC, et al. Clinico-Epidemiologic study on the Abuse, Misuse, and Adverse Effects of Topical Dermatologic Drugs. Korean J Dermal. 2003;41(9):1129-35.
  3. JH Lee. Updates on Biologics in the Management of Psoriasis. Journal of the Korean Society for Psoriasis. 2009;6(1):11.
  4. Park YH, Cheong SH, Lee JS, Kim SS, Shin HD. A Literatural Study of Psoriasis. The journal of K.O.M.S. 1989;9(1):131-6.
  5. Kim NK, Hwang CY, Lim GS. The Oriental and Occidental bibliographic Study of Psoriasis. The Journal of Oriental Medical Surgery Ophthalmology & Otolaryngology. 1999;12(1):171.
  6. Hong SH. Reviewing Research on Korean medical treatment of Psoriasis. The Journal of Korean Medical Ophthalmology & Otolaryngology & Dermatology. 2013;26(4):26-42. https://doi.org/10.6114/jkood.2013.26.4.026
  7. Yang JI. Lee KH, Kim YS, Shin MK, Yoo JH, Chang GT. A Report on Liver Function Tests of 82 Psoriasis Patients Taking Herbal Medication over 3 Months viewing Research on Korean medical treatment of Psoriasis. The Journal of Korean Oriental Medicine. 2012;33(3):95-104.
  8. Camila H, Mariana R, Mariana SA, Sergio T, Monica LA. Sleep Loss and Cytokines Levels in an Experimental Model of Psoriasis. 2012; 0051183. Available at: URL:http://journalss.plos.org/article?id=10.1371/journal.pone.0051183. Accessed Oct. 15, 2014
  9. Jang JS, Jung IC, Lee SR. The Literature Review on th Etiologic Theory of Insomnia. Journal of Oriental Medical Academy in Daejeon University. 2014;13(1):341-342.
  10. The Compilation committee. Oriental Pathology. Seoul:Haneuimonhwasa. 2007:394-396.
  11. Cheng GP. Yixuexinwu. Seoul:Seowondang. 1994:224.
  12. Fredriksson T, Pettersson U. Severe psoriasis-oral therapy with a new retinoid. Dermatologica. 1978;157(4):238-44. https://doi.org/10.1159/000250839
  13. Jacobs GD, Pace-Schott EF, Stickgold R, Otto MW. Cognitive behavior therapy and pharmacotherapy for insomnia. Arch InternMed. 2004;164:1888-96. https://doi.org/10.1001/archinte.164.17.1888
  14. The Compilation committe. Dermatology. 4th ed. Seoul:Yeomungak. 2002:221-30.
  15. Kang WH. Atlas of Skin Disease. Seoul: Hanmibook. 2003:121.
  16. Chao YF, Zhubingyuanhoulun. Seoul:Jungdam. 1985:461-2,796-8.
  17. Park YG, Kim YK, Yun YG. A review on composition, action, compatibility of ingredients, clinical application of Gwibitang. The korean journal of oriental medical prescription. 2007;15(2):6.
  18. Kim JH, Lee JK, Ha HK, Seo CS, Lee MY, Lee HY. Analysis of Studies on Guibi-tang (Guipitang) for Fundamental Establishment of Evidence Based Medicine(EBM). J. of Oriental Neuropsychiatry. 2009;20(3):213.
  19. Lee DJ, Kim SH. An Experimental Study on the Influence that the Medicinal Decoction of Kwi-Bi-Tang Affects Sleeping Hours and Sedation. K. H. Univ. Med. J. 1979:2(1):163-169.

Cited by

  1. 상한론에 근거하여 오수유탕을 이용하여 호전된 건선 치험 1례 vol.24, pp.1, 2015, https://doi.org/10.14374/hfs.2016.24.1.53
  2. 건선 한약제제 임상시험 가이드라인 개발을 위한 관련 국내외 가이드라인과 기존 건선치료 한약제제 연구와의 비교 vol.29, pp.2, 2016, https://doi.org/10.6114/jkood.2016.29.2.012
  3. 건선의 변증유형과 한약치료에 대한 증례 분석 vol.31, pp.1, 2015, https://doi.org/10.7778/jpkm.2017.31.1.001
  4. 불면장애에 사용된 귀비탕의 동질성 연구 -CNKI에서 검색한 무작위배정 임상연구를 중심으로- vol.29, pp.3, 2015, https://doi.org/10.7231/jon.2018.29.3.145
  5. CARE 지침에 따른 대한한의학회지의 증례 보고에 대한 질 평가 연구: 2015년~2020년 증례 보고를 중심으로 vol.41, pp.2, 2015, https://doi.org/10.13048/jkm.20016