Journal of the Korean Medical Association (대한의사협회지)

Korean Medical Association (대한의사협회)
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Diagnosis and management of amyotrophic lateral sclerosis

근위축성 측삭경화증의 진단과 치료

  • Shin, Je-Young (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Lee, Kwang-Woo (Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine)
  • 신제영 (서울대학교 의과대학 서울대병원 신경과) ;
  • 이광우 (서울대학교 의과대학 서울대병원 신경과)
  • Received : 2014.11.26
  • Accepted : 2014.12.10
  • Published : 2015.02.10
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Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons. The clinical diagnosis is confirmed by careful history taking, neurologic examination and electromyography. Like other neurodegenerative disease, ALS has many genetic and environmental factors. There are many studies reported about the pathogenesis and treatment of ALS. Many clinical trials are currently in progress. Herein we review about the epidemiology, genetics, pathophysiology, diagnosis and treatment of ALS.

Keywords

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