The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Review of Domestic Experimental Studies of Herbal Medicines for Hyperthyroidism since 2000

갑상선 기능항진증에 대한 국내 한의약 실험연구 고찰 - 2000년 이후

  • Lee, Min-hye (Dept. of Korean Internal Medicine, Gil Korean Medical Hospital, Ga-Chon University) ;
  • Jeon, Chan-yong (Dept. of Korean Internal Medicine, Gil Korean Medical Hospital, Ga-Chon University) ;
  • Kang, Mi Suk (Dept. of Korean Internal Medicine, Gil Korean Medical Hospital, Ga-Chon University) ;
  • Choi, You-kyung (Dept. of Korean Internal Medicine, Gil Korean Medical Hospital, Ga-Chon University)
  • 이민혜 (가천대학교부속 길한방병원 한방내과) ;
  • 전찬용 (가천대학교부속 길한방병원 한방내과) ;
  • 강미숙 (가천대학교부속 길한방병원 한방내과) ;
  • 최유경 (가천대학교부속 길한방병원 한방내과)
  • Received : 2016.10.21
  • Accepted : 2016.11.23
  • Published : 2016.12.30
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Abstract

Objectives: This study reviewed experimental studies on the effects of herbal medicines in treating hyperthyroidism. Methods: We analyzed the experimental studies of herbal medicines done in Korea to treat hyperthyroidism that have been reported since 2000 by searching 4 Korean databases with the keyword "hyperthyroidism". Results: Two single herbal medicines and 15 complex herbal medicines were used in 15 experimental studies. There was 1 clinical study and 14 nonclinical studies, among them, 2 in vitro experiments and 12 in vivo experiments. It was confirmed that the herbal medicines used have improving effects on hyperthyroidism by inhibiting the oversupplied thyroid hormones and hypermetabolic symptoms. Conclusions: There should be further studies on the antioxidative effects and acting mechanisms of herbal medicines and more clinical studies on hyperthyroidism.

Keywords

References

  1. Department of Internal Medicine of kidney system, National College of Korean Medicine. Syngye Naegwahak. Seoul: Koonja publishing company; 2011, p. 279-82.
  2. Korean Endocrine Society. Endocrinology. The 2nd Edition. Seoul: Koonja publishing company; 2011, p. 129.
  3. Kasper D, Braunwald E, Fauci A, Hauser S, Longo D, Jameson J, et al. Harrison's Internal Medicine. Seoul: Book publishing MIP; 2006, p. 2308-23.
  4. Soma Masayoshi. Steps to internal medicine part 9. Seoul: Jeongdam; 2008, p. 55-65.
  5. Byun SH, Kim SI, Kang KH, Lee BC, Ahn YM, Doo HK, et al. The Analysis on Clinical Characteristics of Out-Patients of Oriental Thyroid Clinic. Korean J Orient Int Med 2005;26(1): 213-20.
  6. Lee SH, Choi AR, Goo DM. The clinical study on 1 case of soeumin patient diagnosed as Grave's disease, treated with Palmulgunja-tang and western medicine. Korean J Sasang Constitutional Med 2010;22(4):98-105.
  7. Kim DH, Park SC, Cho MK, Han CW, Choi JY, Kwon JN, et al. Clinical case report of Hyperthyroidism patient treated with only traditional Korean herbal medicine. Korean J Orient Physiology & Pathology 2012;26(3):376-80.
  8. Son HY, Kim BS, Kim KS, Kim SM, Choi HS. A case study about Soyangin heat sensation in the chest patient diagnosed as Hyperthyroidism. Korean J East-West Med 2014;39(1):41-9.
  9. Erdamar H, Demirci H, Yaman H, Erbil MK, Yakar T, Sancak B, et al. The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status. Clinical Chemistry and Laboratory Medicine 2008;47(7):1004-14.
  10. Lee MH, Choi YK. Systemic Reviews of Domestic Experimental Studies of Herbal Medicines Used for Hypothyroidism since 2000. Korean J Orient Int Med 2015;36(4):570-81.
  11. Herbology Editorial Committee of Korean Medicine schools. Herbology. Seoul: Younglimsa; 2011, p. 169-70, 190-3, 233-4, 354-5, 533-8, 581-3, 601-3.
  12. Jang MK. HangjonglyuJungyagjeogImsangeungyong. Beijing: People hygiene publishing company; 1998, p. 316-7.
  13. Jang SS. HyeondaeSilyongHangamJungyag. Beijing: Beijing science and technology publishing company; 1999, p. 133-6.
  14. Lee SJ. Bonchogangmog. Beijing: People hygiene publishing company; 1982, p. 1303-4.
  15. Lee JM. Longevity and Life Preservation In Eastern Medicine. Seoul: Eulyoomunhwasa; 2002, p. 27-278.
  16. Doo HK. Oriental internal medicine of Kidney. Seoul: Foundation of oriental medicine research institute; 1993, p. 850-3, 858-68, 1056-65.
  17. Shin MG, Park G, Maeng UG. GugyeogHyangyag Jibseongbang(ha). Seoul: Younglimsa; 1989, p. 1763, 1772, 1782, 1802, 1828, 1858, 1971, 1985.
  18. Kim CM, Shin MG, Ahn DG, Lee KS. Jungyag daesajeon. Seoul: Jeongdam; 1997, p. 4788-9.
  19. Xiong D, Yu LX, Yan X, Guo C, Xiong Y. Effects of root and stem extracts of Asparagus cochinchinensis on biochemical indicators related to aging in the brain and liver of mice. Am J Chin Med 2011;39:719-26. https://doi.org/10.1142/S0192415X11009159
  20. Wang GD. Jeungchijunseung. Shanghai: Shanghai science and technology publishing company; 1995, p. 347-50, 409.
  21. Hwang UI. DonguiJeongsingwahag. Seoul: Modern medicine book company; 1987, p. 608-892.
  22. Han YS, Park JH. Western and Korean Review of Hyperthyroidism and Hypothyroidism. J East-West Medicine 1997;22(3):17-36.
  23. Park BG. Jeungbo HanbangImsangSasibnyeon. Seoul: Daegwangmunhwasa; 1992, p. 337.
  24. Jeoung YH, Chae BY. Studies on Effects of Sipyukmiyukieum on the Hyperthyroidism. Korean J Orient Med 1988;9(2):98-108.
  25. Beijing Chinese Clinic. Oriental Medicine Clinical Pathology. Seoul: Seongbosa; 1983, p. 70-2.
  26. Go BH. SilyongJunguioegwahag. Shanghai: Shanghai science and technology publishing company; 1982, p. 148-54.
  27. Kim CJ. Literatural Examination on Hyperthyroidism. Research Institute of Korean Medicine Symposium, Daejon University 1998:807-15.
  28. Lee KG, Lee NG, Nam TS. The Literature Study on Goiter. Korean J Orient Medical Pathology 1996;10(1):25-31.
  29. Guyton. Textbook of Medical Physiology. Seoul: Jeongdam; 2002, p. 1002-12.
  30. Min HG, Choi YG, Go CS, Heo GB, Lee TH, Lee HG. Endocrinology. Seoul: Korea Medical Book Publishing Company; 1999, p. 155-9, 164-5, 256-9.
  31. Lee GN. Clinical Pathalagy File. The 3rd edition. Seoul: Medi-Culture Press; 2003, p. 417-22.
  32. Venditti P, Di Meo S. Thyroid hormone-induced oxidative stress. Cell Mol Life Sci 2006;63:414-34. https://doi.org/10.1007/s00018-005-5457-9
  33. Subudhi U, Das K, Paital B, Bhanja S, Chainy GB. Alleviation of enhanced oxidative stress and oxygen consumption of L-thyroxine induced hyperthyroid rat liver mitochondria by vitamin E and curcumin. Chem Biol Interact 2008;173:105-14. https://doi.org/10.1016/j.cbi.2008.02.005
  34. Messarah M, Boumendjel A, Chouabia A, Klibet F, Abdennour C, Boulakoud Ms, et al. Influence of thyroid dysfunction on liver lipid peroxidation and antioxidant status in experimental rats. Exp Toxicol Pathol 2010;62:301-10. https://doi.org/10.1016/j.etp.2009.04.009
  35. Baydas B, Meral I. Effects of melatonin on lipid peroxidation and anti-oxidant enzyme activity in rats with experimentally induced hyperthyroidism. Clin Exp Pharmacol Physiol 2005;32:541-4. https://doi.org/10.1111/j.1440-1681.2005.04228.x

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