Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Permeation Characteristics of Hazardous Substances in Tattoo Dye using Franz Diffusion Cells

Franz Diffusion Cell을 이용한 문신용 염료 내 유해물질의 피부 투과특성 연구

  • Park, Kyo-Hyun (Department of Public Health, College of Natural Sciences, Keimyung University) ;
  • Jung, Se-Hoon (Department of Public Health, College of Natural Sciences, Keimyung University) ;
  • Shin, Ho-Sang (Department of Environmental Education, College of Education, Kongju National University) ;
  • Kim, Bae-Hwan (Department of Public Health, College of Natural Sciences, Keimyung University)
  • 박교현 (계명대학교 자연과학대학 공중보건학전공) ;
  • 정세훈 (계명대학교 자연과학대학 공중보건학전공) ;
  • 신호상 (공주대학교 사범대학 환경교육과) ;
  • 김배환 (계명대학교 자연과학대학 공중보건학전공)
  • Received : 2015.11.17
  • Accepted : 2016.02.16
  • Published : 2016.02.29
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Abstract

Objectives: The purpose of this study is to determine the exposure risk to tattoo components by analyzing skin absorption using the in vitro method. Tattoos are commonly used for cosmetic purposes, and the skin of not only the operator but of the people who are undergoing the cosmetic procedure is continuously exposed to hazardous chemicals. Methods: Skin permeation risk determination was conducted by the in vitro Franz diffusion cell method according to the ingredient types of tattoo dyes, such as volatile organic compounds (VOCs), non-volatile organic compounds and heavy metals, using hairless mouse full skin and human cadaver epidermis. Results: The major components with good skin penetration for each type of tattoo dye ingredient were clarified. Among the tatto dye ingredients, 1,2-Dichlorobenzene, Zn, Al, Pb and Ti showed good skin penetration. Most of the skin transmission rates were higher in hairless mouse full skin than in human cadaver epidermis. Conclusion: A possible exposure risk to hazardous substances in tattoo dyes was confirmed from this study. These results are expected to provide a positive contribution to the establishment of management regulations for tattoo dyes.

Keywords

References

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