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Current Trends in Intervention Studies of Hwabyung in Korean Medicine

화병의 한의학적 치료에 대한 연구동향

  • Suh, Hyo-Weon (Department of Neuropsychiatry, Graduate School, Kyung Hee University) ;
  • Choi, Eun-Ji (Department of Neuropsychiatry, Graduate School, Kyung Hee University) ;
  • Kim, Sang-Ho (Department of Neuropsychiatry, Pohang Oriental Hospital of Daegu Haany University) ;
  • Kim, Dong Hee (Department of Oriental Neuropsychiatry, Dongeui Oriental Medical Hospital of Dongeui University) ;
  • Kim, Lak-Hyung (Department of Neuropsychiatry, College of Korean Medicine, Woo-Suk University) ;
  • Kim, Jong-Woo (Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jae-Hyok (Department of Neuropsychiatry, College of Korean Medicine, Semyung University) ;
  • Lim, Jae-Hwan (Kyung Hee Brightmind Korean Medical Clinic) ;
  • Choi, Woo-Jin (Department of Neuropsychiatry, College of Korean Medicine, Sangji University) ;
  • Chung, Sun-Yong (Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University)
  • 서효원 (경희대학교 대학원 한방신경정신과) ;
  • 최은지 (경희대학교 대학원 한방신경정신과) ;
  • 김상호 (대구한의대학교 포항한방병원 신경정신과) ;
  • 김동희 (동의대학교 부속한방병원 한방신경정신과) ;
  • 김락형 (우석대학교 한의과대학 한방신경정신과학교실) ;
  • 김종우 (경희대학교 한의과대학 한방신경정신과학교실) ;
  • 이재혁 (세명대학교 한의과대학 한방신경정신과학교실) ;
  • 임재환 (경희밝은마음 한의원) ;
  • 최우진 (상지대학교 한의과대학 한방신경정신과학교실) ;
  • 정선용 (경희대학교 한의과대학 한방신경정신과학교실)
  • Received : 2016.11.25
  • Accepted : 2016.12.21
  • Published : 2016.12.30

Abstract

Objectives: To determine the general characteristics of clinical studies about Hwabyung and assess their limitations and alternatives. Methods: Clinical studies that examined the effects of traditional Korean medicine intervention on Hwabyung were included in this study. A systematic search of English, Chinese, Japanese, and Korean databases was performed. The characteristics of included articles were described and those articles were assessed by Risk of Bias (RoB) tool or Risk of Bias for Nonrandomized Studies (RoBANS) tool. Results: Sixteen articles were selected from 1,826 articles. Most clinical studies about Hwabyung were published in Korea. The number of conducted trials was insufficient. The prevailing study design was randomized controlled trial. Traditional Korean medicine intervention used in the trials were acupuncture, herbal medicine, counselling, meditation, emotional freedom technique (EFT), music therapy, art therapy, and multi intervention program. Herbal medicine study used placebo as control while non-pharmacological intervention study mostly used no treatment as control. Most of the trials were supported by the government. Therefore, financial conflict of interest might not exist for results. We judged that some studies had a high risk of bias. In general, most of the studies with a high risk of bias were non-pharmacological intervention studies, and the risk of bias was mainly due to lack of blinding. Conclusions: More clinical studies of Hwabyung are needed. There are some issues about a suitable comparison and effective blinding strategy for non-pharmacological study. Improving methodological quality is required.

Keywords

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