DOI QR코드

DOI QR Code

A Test for Psychobiologic Entropy Model on Cancer Related Fatigue among Patients with Solid Tumors

고형암 환자의 암성피로에 대한 정신생리학적 엔트로피 모델 검증

  • 오창희 (화순전남대학교병원) ;
  • 박현영 (호남대학교 간호학과) ;
  • 이지숙 (호남대학교 간호학과) ;
  • 최자윤 (전남대학교 간호대학.간호과학연구소)
  • Received : 2015.09.25
  • Accepted : 2016.02.09
  • Published : 2016.02.29

Abstract

Purpose: The purpose of this study was to test a Winningham's psychobiologic entropy model (PEM) on cancer related fatigue (CRF) among patients with solid tumors. Methods: Participants consisted of 213 patients with solid tumors recruited from December, 2012 through June, 2013, in a university hospital, in Hwasun, South Korea. Primary symptoms, adjustment, physical activity, status of nutrition and fatigue were measured using structured questionnaires. Collected data were analyzed using SPSS 21.0 and AMOS 21.0 programs. Results: The modified model tested provided a reasonable fit to the data ($x^2=65.80$ [df=30, p<.001], TLI=.92, CFI=.95, RMSEA=.08, SRMR=.07). Primary symptoms (dyspnea, anxiety, depression and insomnia) had direct positive effects on CRF. Adjustment and status of nutrition showed indirect negative effects on CRF. However, the impact of physical activity was not significant. These variables explained 49.2% of the variance of CRF among solid tumor patients. Conclusion: The findings demonstrate that the tested model explain some CRF among solid tumor patients and warrant future research considering the cancer-related clinical factors of the given population.

Keywords

References

  1. Mock V, Atkinson A, Barsevick AM, Berger AM, Cimprich B, Eisenberger MA, et al. Cancer-related fatigue. Clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network: JNCCN. 2007;5(10):1054-78. https://doi.org/10.6004/jnccn.2007.0088
  2. Hofman M, Ryan JL, Figueroa-Moseley CD, Jean-Pierre P, Morrow GR. Cancer-related fatigue: the scale of the problem. Oncologist. 2007;12(1):4-10. http://dx.doi.org/10.1634/theoncologist.12-S1-4
  3. Horneber M, Fischer I, Dimeo F, Ruffer JU, Weis J. Cancerrelated fatigue: epidemiology, pathogenesis, diagnosis and treatment. Deutsches Arzteblatt International. 2012;109(9): 161-72. http://dx.doi.org/10.3238/arztebl.2012.0161
  4. Winningham ML, Nail LM, Burke MB, Brophy L, Cimprich B, Jones LS, et al. Fatigue and the cancer experience: the state of the knowledge. Oncology Nursing Forum. 1994;21(1):23-36.
  5. Bower JE, Lamkin DM. Inflammation and cancer-related fatigue: mechanism, contributing factors, and treatment implications. Brain, Behavior, and Immunity. 2013;30:48-S57. http://dx.doi.org/10.1016/j.bbi.2012.06.011
  6. AI-Majid S, Gray P. A biobehavioral model for the study of exercise interventions in cancer-related fatigue. Biological Research for Nursing. 2009;10(4):381-91. https://doi.org/10.1177/1099800408324431
  7. Choi JY, Kang HS. Influencing factors for fatigue in cancer patients. Journal of Korean Academy Nursing. 2007;37(3):365-72. http://dx.doi.org/10.1177/1099800408324431
  8. Pearson EJ, Morris ME, McKinstry CE. Cancer-related fatigue: a survey of health practitioner knowledge and practice. Supportive Care in Cancer. 2015; [Epub ahead of print].
  9. Winningham, M. The role of exercise in cancer therapy. In: Eistinger M, Watson RW, editors. Exercise and disease. Boca Raton, FL: CRC Press, 1992. p. 63-70.
  10. Zordan R, Manitta V, Nandurkar H, Cole-Sinclair M, Philip J. Prevalence and predictors of fatigue in haemo-oncological patients. Internal Medicine Journal 2014;44(10):1013-7. http://dx.doi.org/10.1111/imj.12517
  11. Nail LM, Winningham ML. Fatigue and weakness in cancer patients: the symptom experience. Seminars in Oncology Nursing. 1995;11(4):272-8.
  12. Husain N, Cruickshank K, Husain M, Khan S, Tomenson B, Rahman A. Social stress and depression during pregnancy and in the postnatal period in British Pakistani mothers: a cohort study. Journal of Affective Disorders. 2012;140(3):268-76. http://dx.doi.org/10.1016/j.jad.2012.02.009
  13. Bentler PM, Chou CP. Practical issues in structural modeling. Sociological Methods and Research. 1987;15(1):78-117. http://dx.doi.org/10.1177/0049124187016001004
  14. Kim YJ, Kim JY, Choi IR, Kim MW, Rhodes VA. The index of nausea, vomiting, and retching(Korean translation). Journal of Korean Academy Adult Nursing. 2000;12(2):278-85.
  15. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. British Medical Journal. 1983;67(6):361-70.
  16. Shin JS, Lee YB. The effects of social supports on psychosocial well-being of the unemployed. Korean Journal of Social Welfare. 1999;37:241-69.
  17. Cho YW, Song ML, Morin CM. Validation of a Korean version of the insomnia severity index. Journal of Clinical Neurology. 2014;10(3):210-5. http://dx.doi.org/10.3988/jcn.2014.10.3.210
  18. Bauer J, Capra S, Ferguson M. Use of the scored patient-generated subjective global assessment(PG-SGA) as a nutrition assessment tool in patients with cancer. European Journal of Clinical Nutrition. 2002;56:779-85. https://doi.org/10.1038/sj.ejcn.1601412
  19. Lee MS. Relationship between breast cancer and coping style or emotional adaptation [master thesis]. Seoul: Seoul National University; 1997.
  20. Oh JY, Yang YJ, Kim BS, Kang JH. Validity and reliability of Korean version of International Physical Activity Questionnaire (IPAQ) short form. Korean Journal of Family Medicine. 2007;28(7):532-41. http://dx.doi.org/10.4082/kjfm.2012.33.3.144
  21. Mendoza TR, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK, et al. The rapid assessment of fatigue severity in cancer patients: use of the brief fatigue inventory. Cancer. 1999;85(5):1186-96. https://doi.org/10.1002/(SICI)1097-0142(19990301)85:5<1186::AID-CNCR24>3.0.CO;2-N
  22. Valentine AD, Meyers CA. Cognitive and mood disturbance as causes and symptoms of fatigue in cancer patients. Cancer. 2001;92(6 Suppl):1694-8. https://doi.org/10.1002/1097-0142(20010915)92:6+<1694::AID-CNCR1499>3.0.CO;2-S
  23. Porock D, Beshears B, Hilton P, Anderson C. Nutritional, functional, an emotional characteristics related to fatigue in patients during and after biochemotherapy. Oncology Nursing Forum. 2005;32(3):661-7. https://doi.org/10.1188/05.ONF.661-667
  24. Mitchell SA, Beck SL, Hood AE, Moore K, Tanner ER. Putting evidence into practice: evidence-based interventions for fatigue during and following cancer and its treatment. Clinical Journal of Oncology Nursing. 2007;11(1):99-113. http://dx.doi.org/10.1188/07.CJON.99-113
  25. Cramp F, Byron-Daniel J. Exercise for the management of cancer-related fatigue in adults. The Cochrane Database of Systematic Reviews. 2012;11:CD006145. http://dx.doi.org/10.1002/14651858.CD006145.pub3
  26. Seo YM, Oh HS, Seo WS, Kim HS. Comprehensive predictors of fatigue for cancer patients. Journal of Korean Academy Nursing. 2006;36(7):1224-31. https://doi.org/10.4040/jkan.2006.36.7.1224
  27. Dirksen SR, Belyea MJ, Epstein DR. Fatigue-based subgroups of breast cancer survivors with insomnia. Cancer Nursing. 2009;32(5):404-11. http://dx.doi.org/10.1097/NCC.0b013e3181a5d05e
  28. Guest DD, Evans EM, Rogers LQ. Diet components associated with perceived fatigue in breast cancer survivors. European Journal of Cancer Care. 2013;22(1):51-9. http://dx.doi.org/10.1111/j.1365-2354.2012.01368.x
  29. Lee YH, Tsai YF, Lai YH, Tsai CM. Fatigue experience and coping strategies in Taiwanese lung cancer patients receiving chemotherapy. Journal of Clinical Nursing. 2008;17(7):876-83. http://dx.doi.org/10.1111/j.1365-2702.2007.02021.x
  30. Minton O, Richardson A, Sharpe M, Hotopf M, Stone P. A systematic review and meta-analysis of the pharmacological treatment of cancer-related fatigue. Journal of the National Cancer Institute. 2008;100(16):1155-66. http://dx.doi.org/10.1093/jnci/djn250

Cited by

  1. 척추마취 전립선절제술환자의 음악요법효과에 대한 융합연구 vol.8, pp.1, 2016, https://doi.org/10.15207/jkcs.2017.8.1.097
  2. Pre-post analysis of a social capital-based exercise adherence intervention for breast cancer survivors with moderate fatigue: a randomized controlled trial vol.28, pp.11, 2016, https://doi.org/10.1007/s00520-020-05363-7