Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Some Monascus purpureus Genomes Lack the Monacolin K Biosynthesis Locus

  • Kwon, Hyung-Jin (Department of Biological Science and Bioinformatics, Myongji University) ;
  • Balakrishnan, Bijinu (Department of Biological Science and Bioinformatics, Myongji University) ;
  • Kim, Yeon-Ki (Department of Biological Science and Bioinformatics, Myongji University)
  • Received : 2015.10.30
  • Accepted : 2015.11.26
  • Published : 2016.03.31
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Abstract

Two Monascus purpureus genomes lack the monacolin K biosynthesis locus (mok), while Monascus species are generally assumed to be monacolin K producers. These M. purpureus harbor a fusion of mokA and mokB orthologues. This finding suggests that an ancestral mok locus underwent a deletion event in the M. purpureus genome.

Keywords

References

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