Chemical Constituents of Lonicera maackii Leaves

괴불나무잎(Lonicera maackii)의 성분

  • Kim, Seon Mi (College of Pharmacy, Kangwon National University) ;
  • Won, Yong Hoon (College of Pharmacy, Kangwon National University) ;
  • Jeong, Kai (College of Pharmacy, Kangwon National University) ;
  • Kim, Myong Jo (College of Agriculture and Life Science, Kangwon National University) ;
  • Chun, Wanjoo (School of Medicine, Kangwon National University) ;
  • Yang, Hee Jung (College of Pharmacy, Kangwon National University) ;
  • Kwon, Yongsoo (College of Pharmacy, Kangwon National University)
  • Received : 2016.03.09
  • Accepted : 2016.04.19
  • Published : 2016.06.30

Abstract

Two flavonoid glycosides and three secoiridoide glycosides were isolated from the leaves of Lonicera maackii. On the basis of spectral and physico-chemical data, the structures of isolated compounds were identified as hesperetin-7-O-glucoside (1), luteolin-7-O-${\beta}$-D-glucopyranoside (2), secologanin dimethylacetal (3), epi-vogeloside (4), and vogeloside (5), respectively. Hesperetin-7-O-glucoside (1) was isolated for the first time from this plant.

Keywords

References

  1. 이우철 (1996) 원색 한국기준식물도감, 331, 아카데미서적, 서울.
  2. 배기환 (2000) 한국의 약용식물, 474, 교학사, 서울.
  3. 國家中醫藥管理局 <中華本草> 編纂委員會 (1999) 中華本草 7, 539-540, 上海科學技術出版社, 上海.
  4. Sultana, S., Kamil, M. and Ilyas, M. (1984) Chemical investigation of Lonicera maackii. J. Indian Chem. Soc. 61: 730.
  5. Wang, G. Zhou, X., Yuan, S. and Yang, X. (2010) Chemical constituents in fruit of Lonicera maackii. Zhongguo Yaowu Huaxue Zazhi 20: 211-213.
  6. M. J. L. and Li, J. S. (2013) Chemical constituents from leaves of Lonicera maackii. Xiandai Yaowu Yu Linchuang 28: 476-479.
  7. Marby, T. J., Markham, K. R. and Thomas, M. B. (1970) The Systematic Identification of Flavonoids. Springer - Verlag, New York.
  8. Agrawal, P. K. (1989) Carbon - 13 NMR of Flavonoids. Elsevier, Amsterdam.
  9. Slade, D., Ferreira, D. and Marais, P. J. (2005) Circular dichroism, a powerful tool form the assessment of absolute configuration of flavonoids. Phytochemistry 66: 2177-2215. https://doi.org/10.1016/j.phytochem.2005.02.002
  10. Levai, A. (1998) Utilization fo the chiroptical spectroscopies for the structure elucidation of flavonoids and related benzopyran derivatives. Acta Chim. Slov. 45: 267-284.
  11. Zheng, J., Gao, H., Chen, G., Wu, B. and Wu, L. (2006) Studies on the chemical constituents of the active parts of Mentha spicata L. (I). J. Shenyang Pharm. Univ. 23: 145-147.
  12. Ren, Y. L. and Yang, J. S. (2001) Study on chemical constituents of Saussurea tridac-tyla Sch-Bip. Chin. Pharm. J. 36: 590-593.
  13. 강삼식, 손건호 (2000) 천연물성분 구조결정법, 73-91, 서울대학교 출판부, 서울.
  14. Kawai, H., Kuroyanagi, M. and Ueno, A. (1988) Iridoid glucosides from Lonicera japonica Thunb. Chem. Pharm. Bull. 36: 3664-3666. https://doi.org/10.1248/cpb.36.3664
  15. Kang, W. Y. and Hao, X. J. (2007) Terpenoid glycosides from stem of Luculia pinceana. Zhongguo Zhong Yao Za Zhi. 32: 2606-2609.
  16. Tomassini, L., Francesca Cometa, M., Serafini, M. and Nicoletti, M. (1995) Isolation of secoiridoid artifacts from Lonicera japonica. J. Nat. Prod. 58: 1756-1758. https://doi.org/10.1021/np50125a020