Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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Practical Process Development of AMCA from Recyclable Source MFB

재사용이 가능한 MFB로부터 AMCA의 합성 공정 개발

  • Kim, Jong Cheon (Department of Bio & Nano Chemistry, Kookmin University) ;
  • Ryu, Young (Department of Bio & Nano Chemistry, Kookmin University) ;
  • Kim, Seok Chan (Department of Bio & Nano Chemistry, Kookmin University)
  • 김종천 (국민대학교 생명나노화학과) ;
  • 류영 (국민대학교 생명나노화학과) ;
  • 김석찬 (국민대학교 생명나노화학과)
  • Received : 2016.07.25
  • Accepted : 2016.09.13
  • Published : 2016.10.10
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Abstract

A facile synthesis of 4-(aminomethyl)cyclohexanecarboxylic acid (AMCA) from recyclable methyl 4-formylbenzoate (MFB) was described. In particular, we investigated the best process variables such as catalyst, hydrogen pressure, reaction temperature, and reaction time for AMCA conversion from AMBA through hydrogenation reaction. The best conditions were found to be as follows: the catalyst as [5% Pd/C, 5% Pt/C, 5% Rh/C (1 : 1 : 1)] which is a composite catalyst, the pressure as 30 bar, the reaction time as 8 hours and the reaction temperature at $130^{\circ}C$. Under the condition, a 90% yield (purity 99.9%) for the mass production of AMCA was achieved.

재활용이 가능한 자원인 MFB를 출발 물질로 하여 AMCA의 합성을 진행하였으며, AMBA로부터 AMCA로의 최적의 상업화 합성 조건을 찾고자 촉매, 수소 압력, 반응 온도, 반응 시간 같은 공정 변수를 조사하였다. 최적의 조건은 촉매는 [5% Pd/C : 5% Pt/C : 5% Rh/C (1 : 1 : 1)]의 복합 촉매를 반응 시간은 8 h, 반응 온도는 $130^{\circ}C$, 압력은 30 bar일 때(수율 90%, 순도 99.9%)임을 확인하였다.

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References

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