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Epidemiologic Characteristics of Intentional Poisoning: Emergency Department Based Injury in-depth Surveillance During 2011-2015

의도적 중독으로 응급실을 방문하는 환자들의 특성: 2011-2015년 응급실 손상환자 심층조사 분석

  • Lee, Hak Soo (Department of Emergency Medicine, Yonsei University College of Medicine) ;
  • Han, Juhee (Department of Emergency Medicine, Yonsei University College of Medicine) ;
  • Kim, Ji Hoon (Department of Emergency Medicine, Yonsei University College of Medicine) ;
  • Kim, Sunpyo (Department of Emergency Medicine, College of Medicine, Chosun University) ;
  • Kim, Sun Hyu (Department of Emergency Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Lee, Ji Sook (Department of Emergency Medicine, Ajou University School of Medicine) ;
  • Cho, Gyu Chong (Department of Emergency Medicine, School of Medicine, Hallym University) ;
  • Han, Chul (Department of Emergency Medicine, Ewha Womans University, School of Medicine) ;
  • Park, Joon Min (Department of Emergency Medicine, Inje University Ilsan Paik Hospital) ;
  • Chung, Sung Phil (Department of Emergency Medicine, Yonsei University College of Medicine) ;
  • Kim, Min Joung (Department of Emergency Medicine, Yonsei University College of Medicine)
  • 이학수 (연세대학교 의과대학 응급의학교실) ;
  • 한주희 (연세대학교 의과대학 응급의학교실) ;
  • 김지훈 (연세대학교 의과대학 응급의학교실) ;
  • 김선표 (조선대학교병원 응급의학과) ;
  • 김선휴 (울산대학교병원 응급의학과) ;
  • 이지숙 (아주대학교 의과대학 응급의학교실) ;
  • 조규종 (한림대학교 의과대학 응급의학과) ;
  • 한철 (이화여자대학교 의과대학 응급의학교실) ;
  • 박준민 (인제대학교 일산백병원 응급의학과) ;
  • 정성필 (연세대학교 의과대학 응급의학교실) ;
  • 김민정 (연세대학교 의과대학 응급의학교실)
  • Received : 2017.07.20
  • Accepted : 2017.08.15
  • Published : 2017.12.31

Abstract

Purpose: The purpose of this study was to investigate the epidemiologic characteristics of patients who visited emergency departments (EDs) after intentional poisoning in Korea. Methods: This study retrospectively analyzed the data of of 23 hospitals during a five-year period, between 2011 and 2015. We included patients who inflicted injury to themselves - attempt of suicide - by means of poisoning. Results: A total of 18,121 patients visited an ED after intentional poisoning. Among them, 58.3% were females; however, there were more males among those aged 60 years or older. The mortality rate for males was 8.6%, which was 3.1 times higher than that for females with 2.8%. The most common poison was pesticides (35.4%) in males and sedative-hypnotics (44.0%) in females. The most common causative agent of death was pesticide in both sexes (75.2% and 65.3%, respectively). Since the production of paraquat was discontinued in 2011, the number of deaths from pesticide poisoning has decreased. The mortality rate declined in both males and females, from 12.6% and 4.5% in 2011 to 7.1% and 2.1% in 2015, respectively. Conclusion: In this study, we analyzed the epidemiologic characteristics of intentional poisoning, especially the frequency of suicide attempts by gender and age group, the cause of suicide, and the causative agent. This can be used as basic data for establishing policies to reduce and prevent suicide attempts by poisoning.

Keywords

References

  1. OECD (2016), OECD Factbook 2015-2016: Economic, Environmental and Social Statistics, OECD Publishing, Paris. http://dx.doi.org/10.1787/factbook-2015-en.
  2. Chang SS, Gunnell D, Sterne JA, Lu TH, Cheng AT. Was the economic crisis 1997-1998 responsible for rising suicide rates in East/Southeast Asia? A time-trend analysis for Japan, Hong Kong, South Korea, Taiwan, Singapore and Thailand. Soc Sci Med 2009;68:1322-31. https://doi.org/10.1016/j.socscimed.2009.01.010
  3. Kim H, Kim B, Kang SG, Kim MD, Kim MH, Kim SI, et al. Attempted Suicides in South Korea: A Multi-Center Analysis of Causes, Methods, and Psychiatric Diagnoses of Suicidal Attempters in 2013. Korean J Biol Psychiatry 2015;22:187-94.
  4. Lee JH, Oh SH, Park KN, Youn CS, Kim SH, Jeong WJ, et al. Epidemiologic Study of Poisoned Patients Who Presented to the Emergency Department of a High end Medical Facility in Seoul 1998-2009. J Korean Soc Clin Toxicol 2010;8:7-15.
  5. Kim JH, Cho JS, Kim JJ, Lim YS, Yang HJ, Lee G. Comparison of Epidemiology and Outcomes of Patients with Intentional Poisoning by Age Groups: Single Center Observation Study. J Korean Soc Clin Toxicol 2016;14:129-35. https://doi.org/10.22537/jksct.2016.14.2.129
  6. Jang N, Kim J, Park WB, Cho JS, Hyun SY, Lim YS, et al. Efficacy of a Program Associated with a Local Community of Suicide Attempters who Visited a Regional Emergency Medical Center. J Korean Soc Emerg Med 2012;23:696-704.
  7. World health organization (WHO). Guidelines for poison control. 2017. Available at http://www.who.int/ipcs/publications/training_poisons/guidelines_poison_control/en/ (cited 16 JULY, 2017).
  8. Spiller HA, Appana S, Brock GN. Epidemiological trends of suicide and attempted suicide by poisoning in the US: 2000-2008. Leg Med (Tokyo) 2010;12:177-83. https://doi.org/10.1016/j.legalmed.2010.04.005
  9. Kumar TS, Kanchan T, Yoganarasimha K, Kumar GP. Profile of unnatural deaths in Manipal, Southern India 1994-2004. J Clin Forensic Med 2006;13:117-20. https://doi.org/10.1016/j.jcfm.2005.10.005
  10. Jors E, Christoffersen M, Veirum NH, Aquilar GC, Morant RC, Konradsen F. Suicide attempts and suicides in Bolivia from 2007 to 2012: pesticides are the preferred method - females try but males commit suicide! Int J Adolesc Med Health 2014;26:361-7.
  11. O'Neill S, Corry C, McFeeters D, Murphy S, Bunting B. Suicide in Northern Ireland: An Analysis of Gender Differences in Demographic, Psychological, and Contextual Factors. Crisis 2016;37:13-20. https://doi.org/10.1027/0227-5910/a000360
  12. Hawton K. Sex and suicide. Gender differences in suicidal behaviour. Br J Psychiatry 2000;177:484-5. https://doi.org/10.1192/bjp.177.6.484
  13. Moscicki EK. Gender differences in completed and attempted suicides. Ann Epidemiol 1994;4:152-8. https://doi.org/10.1016/1047-2797(94)90062-0
  14. Mergl R, Koburger N, Heinrichs K, Szekely A, Toth MD, Coyne J, et al. What Are Reasons for the Large Gender Differences in the Lethality of Suicidal Acts? An Epidemiological Analysis in Four European Countries. PLoS One 2015;10:e0129062. https://doi.org/10.1371/journal.pone.0129062
  15. Cibis A, Mergl R, Bramesfeld A, Althaus D, Niklewski G, Schmidtke A, et al. Preference of lethal methods is not the only cause for higher suicide rates in males. J Affect Disord 2012;136:9-16. https://doi.org/10.1016/j.jad.2011.08.032
  16. Moller-Leimkuhler AM. The gender gap in suicide and premature death or: why are men so vulnerable? Eur Arch Psychiatry Clin Neurosci 2003;253:1-8.
  17. Houle J, Mishara BL, Chagnon F. An empirical test of a mediation model of the impact of the traditional male gender role on suicidal behavior in men. J Affect Disord 2008;107:37-43. https://doi.org/10.1016/j.jad.2007.07.016
  18. Boenisch S, Bramesfeld A, Mergl R, Havers I, Althaus D, Lehfeld H, et al. The role of alcohol use disorder and alcohol consumption in suicide attempts--a secondary analysis of 1921 suicide attempts. Eur Psychiatry 2010;25:414-20.
  19. Sher L, Oquendo MA, Richardson-Vejlgaard R, Makhija NM, Posner K, Mann JJ, et al. Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders. J Psychiatr Res 2009;43:901-5. https://doi.org/10.1016/j.jpsychires.2009.01.005
  20. Li X, Phillips MR, Cohen A. Indepth interviews with 244 female suicide attempters and their associates in northern China: understanding the process and causes of the attempt. Crisis 2012;33:66-72. https://doi.org/10.1027/0227-5910/a000108
  21. Chen YY, Wu KC, Yousuf S, Yip PS. Suicide in Asia: opportunities and challenges. Epidemiol Rev 2012;34:129-44. https://doi.org/10.1093/epirev/mxr025
  22. Hovda KE, Bjornaas MA, Skog K, Opdahl A, Drottning P, Ekeberg O, et al. Acute poisonings treated in hospitals in Oslo: a one-year prospective study (I): pattern of poisoning. Clin Toxicol (Phila) 2008;46:35-41. https://doi.org/10.1080/15563650601185969
  23. Islambulchilar M, Islambulchilar Z, Kargar-Maher MH. Acute adult poisoning cases admitted to a university hospital in Tabriz, Iran. Hum Exp Toxicol 2009;28:185-90. https://doi.org/10.1177/0960327108099679
  24. Goksu S, Yildirim C, Kocoglu H, Tutak A, Oner U. Characteristics of acute adult poisoning in Gaziantep, Turkey. J Toxicol Clin Toxicol 2002;40:833-7. https://doi.org/10.1081/CLT-120016953
  25. Avsarogullari L, Senol V, Akdur O, Akin A, Durukan P, Ozkan S. Characteristics of acute adult poisonings in a university hospital emergency department in central Turkey: a threeyear analysis. J Pak Med Assoc 2012;62:129-33.
  26. Mew EJ, Padmanathan P, Konradsen F, Eddleston M, Chang SS, Phillips MR, et al. The global burden of fatal self-poisoning with pesticides 2006-15: Systematic review. J Affect Disord 2017;219:93-104. https://doi.org/10.1016/j.jad.2017.05.002
  27. Page A, Liu S, Gunnell D, Astell-Burt T, Feng X, Wang L, et al. Suicide by pesticide poisoning remains a priority for suicide prevention in China: Analysis of national mortality trends 2006-2013. J Affect Disord 2017;208:418-23. https://doi.org/10.1016/j.jad.2016.10.047
  28. Knipe DW, Chang SS, Dawson A, Eddleston M, Konradsen F, Metcalfe C, et al. Suicide prevention through means restriction: Impact of the 2008-2011 pesticide restrictions on suicide in Sri Lanka. PLoS One 2017;12:e0172893. https://doi.org/10.1371/journal.pone.0172893
  29. Cha ES, Chang SS, Gunnell D, Eddleston M, Khang YH, Lee WJ. Impact of paraquat regulation on suicide in South Korea. Int J Epidemiol 2016;45:470-9. https://doi.org/10.1093/ije/dyv304
  30. Myung W, Lee GH, Won HH, Fava M, Mischoulon D, Nyer M, et al. Paraquat prohibition and change in the suicide rate and methods in South Korea. PLoS One 2015;10:e0128980. https://doi.org/10.1371/journal.pone.0128980

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