Journal of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회지)

Korean Society of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회)
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Fully automated radiosynthesis of [68Ga]edotreotide ([68Ga]DOTA-TOC) and its quality controls

  • Park, Hyun Sik (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • Lee, Hong Jin (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • An, Hyun Ho (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • Moon, Byung Seok (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • Lee, Byung Chul (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • Lee, Won Woo (Department of nuclear medicine, Seoul National University Bundang Hospital) ;
  • Kim, Sang Eun (Department of nuclear medicine, Seoul National University Bundang Hospital)
  • Received : 2017.12.07
  • Accepted : 2017.12.21
  • Published : 2017.12.30
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Abstract

$^{68}Ga-PET$ is of growing importance in the practice of nuclear medicine diagnostic imaging for neuroendocrine tumors as well as prostate cancers. Following this interests, we herein present the radiosynthesis process of [$^{68}Ga$]edotreotide ([$^{68}Ga$]DOTA-TOC) based on the fully automated procedure for clinical doses that can be provided the reduction of radiation exposure and high reproducibility. The quality controls of clinical doses in compliant with European Pharmacopoeia are also discussed.

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References

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