Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
권호 표지
DOI QR코드

DOI QR Code

Convergence Study of Cell Viability and Vascular Relaxtion of Hanbang-tea Prescrpition

한방차 조성물의 세포활성과 혈관이완 효과에 대한 융합적 연구

  • Park, Sung-Hye (Dept. of Food and Nutrition, Kwangju Women' University) ;
  • Min, Je-Ho (Dept. of Alternative Medicine Kwangju Women' University)
  • 박성혜 (광주여자대학교 식품영양학과) ;
  • 민제호 (광주여자대학교 대체의학과)
  • Received : 2017.01.10
  • Accepted : 2017.02.20
  • Published : 2017.02.28
Download PDF
⟨ Previous Next ⟩

Abstract

This study was aimed to secure the basis for developing the hangbang-tea may help promote healthy blood vessels by natural herbal ingredients formulated in accordance with the basic principles of oriental medicinal theory. We investigated the vessels contracted by concentrations and safety assessment carried out by the cell viability of Taraxaci Herba, Gardeniae Fructus, Chrysanthemum indicum and Lonicerae Flos composition and concentration. We found cell survival were higher than the control group show a beneficial trend in the growth of normal liver and kidney cells. As a results of this study will be the basis to develop the hangbang-tea differentiated in the future oriental medicine resources. Medicinal resources will be hangbang-tea based on clinical trials utilizing herbal western and oriental medicine convergence principle and vascular relaxation mechanism.

본 연구는 혈관 활성에 도움이 되는 한방차를 개발하고, 섭취효능에 대한 동 서 융합적인 접근 필요성에 대한 기초자료로 사용하고자 하였다. 이에 따라 기미론에 따라 혈관 활성을 가질 수 있는 포공영(Taraxaci Herba), 치자(Gardeniae Fructus), 감국(Chrysanthemum indicum) 및 금은화(Lonicerae Flos)를 선정하여 조성물을 만들고 각각 재료와 조성물의 영양성분, 조성물이 세포활성에 미치는 영향 및 수축혈관에 대한 이완정도를 분석하였다. 기미론적 원리에 따른 한방차 조성물은 체내 열을 제거하고 혈액순환을 촉진할 수 있는 효능을 가지고 있음을 알 수 있었다. 네 가지를 재료를 배합한 조성물은 세포활성에 유익한 영향을 미치고 있음을 확인하였다. 또한 조성물은 수축혈관에 대해 이완효과를 가지고 있었고 조성물의 농도가 높을수록 수축된 혈관의 이완효과가 큰 것으로 관찰되어 이 조성물이 혈관 활성에 긍정적 영향을 주고 있음을 확인하였다. 본 연구는 한방차 조성물의 기미 특성과 현대 영양학의 특성이 융합된 섭취효능을 제시하였다고 사료된다.

Keywords

References

  1. B. J. Han, G. J. Lee, J. E. Song, "A research on the traditional food materials for developing medicinal food and the direction of applying the theories of oriental medicine", J East Asian Soc Dietary Life, Vol. 15, No. 3, pp. 346-356, 2005.
  2. I. J. Han, "Integrated research of Qi-Flavor theory meaning and nutritional composition in Myeonghwa Yacksun Cha", Ph. D. dissertation, Wonkwang University, 2015.
  3. S. H. Park, G. Y. Kim, "Oriental diet therapy area approach of Reajerksodo-tang", Korean J Food & Nutr, Vol. 23, No. 2, pp. 285-290, 2010.
  4. Cui X, D. H. Lee, "Study on the drug treatment of drugs to treat 'Feiri' by 'Qiweilun', The J Applied Oriental Medicine, Vol. 10, No. 2, pp. 49-55, 2010.
  5. I. R. Kim, "A study on the literal research Kimi-theory", Korean J Ori Med, Vol. 3, No. 1, pp. 169-181, 1975.
  6. Compilation Committee of Chinese Medicine Thesaurus, Compilation of Chinese Medicine Thesaurus. Seoul : Jeondam Publishing, 2003.
  7. J. H. Han, Y. J. Song, S. J. Park, S. H. Park, "Analysis of nutritional composition and effects of Yak-sun tea prescription from oriental medicinal herbs for serum lipid level and homocystein content", J Korean Soc Food Si Nutr, Vol. 35, No. 2, pp. 557-564, 2006. https://doi.org/10.3746/jkfn.2006.35.5.557
  8. W. J. Kim, H. W. Cho, S. H. Park, "Nutritional characteristics and stability in cell of the Yak-sun tea for coronary heart disease", Korean J Oriental Pathology, Vol. 21, No. 1, pp. 219-225, 2007.
  9. I. S. Choi, E. J. Cha, Y. R. Lee, J. K, Kim, "Antioxidant and anticnacer activities of Yak-sun tea prepared by oriental medicinal herbs", Korean J Food & Nutr, Vol. 25, No. 3, pp. 447-453, 2012. https://doi.org/10.9799/ksfan.2012.25.3.447
  10. J. H. Han, Y. J. Song, S. H. Park, "Development of drink from composition with medicinal plants and evaluation of its physiological function in aorta relation" Korean J Oriental & Pathology, Vol. 18, No. 4, 1078-1082, 2004.
  11. A.O.A.C., Official Methods of Analysis. 14th-ed., Association of official analytical chemists. Washington D.C. : 1984.
  12. A.O.A.C.. Official Methods of Analysis. 15th-ed., Association of official analytical chemists. Washington D.C. : 1990.
  13. F. D. Dnizot, L. Rita, "Rapid colorimetric assay for cell growth and survival", J Immunol Methods, Vol. 22, No. 8, pp. 271-277, 1986.
  14. S. H. Park, H. S. Cui, "Characteristics and nutrirional approaching of Sun-Jup in oriental medicinal diet therapy", Korean J Oriental Physiology & Pathology, Vol. 20, No. 3. pp. 753-758, 2006.
  15. Y. S. Park, "Development of functional beverages using distilled extract of Korean medicinal herb", J East Asian Soc Dietary Life, Vol. 17, No. 3, pp. 384-392, 2005.
  16. S. H. Park, "Qi-Flavor Theory' meaning, nutrient content and anti-oxidative activity of oriental medicinal materials with clear heat effect", Korean J Food Culture, Vol. 31, No. 2, pp. 42-50, 2016. https://doi.org/10.7318/KJFC/2016.31.1.042
  17. S. H. Lim, J. B. Kim, Y. S. Choi, Y. M. Park, H. J. Kim, "National standard food composition tables provide the infrastructure for food and nutrition research according research according to policy and industry". Korean J Food & Nutr, Vol. 26, No. 4, pp. 886-894, 2013. https://doi.org/10.9799/ksfan.2013.26.4.886
  18. S. H. Park, "Effects of Yak-sun tea prescription from oriental medicinal herbs for serum lipid levels and oxidative stress in hyperlipidemic women", Korean J Oriental & Pathology, Vol. 20, No. 5, pp.1180-1186, 2006.