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Comparative, randomized, double-blind clinical study of alveolar ridge preservation using an extracellular matrix-based dental resorbable membrane in the extraction socket

  • Chang, Hyeyoon (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Kim, Sulhee (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Hwang, Jin wook (ESTeam Paris Sud, INSERM UMR-S 935, Paris-Sud University, Paris-Saclay University) ;
  • Kim, Sungtae (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Koo, Ki-Tae (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Kim, Tae-Il (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Seol, Yang-Jo (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Lee, Yong-Moo (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Ku, Young (Department of Periodontology, Seoul National University School of Dentistry) ;
  • Lee, Jong-Ho (Department of Oral and Maxillofacial Surgery, Seoul National University School of Dentistry) ;
  • Rhyu, In-Chul (Department of Periodontology, Seoul National University School of Dentistry)
  • Received : 2017.05.08
  • Accepted : 2017.06.01
  • Published : 2017.06.30

Abstract

Purpose: The aim of this study was to radiographically and clinically compare the effect of extracellular matrix (ECM) membranes on dimensional alterations following a ridge preservation procedure. Methods: One of 2 different ECM membranes was applied during a ridge preservation procedure. A widely used ECM membrane (WEM; Bio-Gide, Geistlich Biomaterials, Wolhusen, Switzerland) was applied in the treatment group and a newly developed ECM membrane (NEM; Lyso-Gide, Oscotec Inc., Seongnam, Korea) was applied in the control group. Cone-beam computed tomography (CBCT) scans and alginate impressions were obtained 1 week and 6 months after the ridge preservation procedure. Results were analyzed using the independent t-test and the nonparametric Mann-Whitney U test. Results: There were no significant differences between the ECM membranes in the changes in the dimension, width, and height of the extraction socket or the quantity of bone tissue. Conclusions: The NEM showed comparable clinical and radiographic results to the WEM following the ridge preservation procedure.

Keywords

References

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