The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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Efficacy of Herbal Medicines for the Treatment of Psoriasis : Systematic Review and Meta-analysis

건선의 한약치료 효과에 대한 체계적 문헌 고찰과 메타 분석

  • Ryu, Deok-Hyun (Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology, College of Oriental Medicine, Daejeon University) ;
  • Ryu, Deok-Seon (Dept. of Biomedical Laboratory Science, Soonchunhyang University) ;
  • Roh, Seok-Sun (Dept. of Oriental Medical Ophthalmology & Otolaryngology & Dermatology, College of Oriental Medicine, Daejeon University)
  • 류덕현 (대전대학교 한의과대학 안이비인후피부과) ;
  • 류덕선 (순천향대학교 의료과학대학 임상병리학과) ;
  • 노석선 (대전대학교 한의과대학 안이비인후피부과)
  • Received : 2017.06.16
  • Accepted : 2017.08.04
  • Published : 2017.08.25
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Abstract

Objectives : This study aimed to validate the effect of herbal medicine intervention to relieve the symptoms of psoriasis using systematic review and meta-analysis and provide the newest reason of effectiveness of Korean medicine to psoriasis. Methods : Data were collected through electronic database including Pubmed, Cochrane CENTRAL, NDSL OASIS, Koreantk. Two experts assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool after searching, reviewing and selecting papers. Data were analyzed using Review Manager(RevMan) 5.3 and Comprehensive Meta Analysis 2.0. Results : Total number of selected trials was 16 randomized controlled trials. This study evaluated the risk of bias and effectiveness of herbal medicine to psoriasis. There were high frequency uncertain in selection bias, performance bias and detection bias. In this meta-analysis, Korean medicine treatment was more effective than western medicine (ES:0.507, 95%CI:0.147-0.867) and placebo (ES:0.955, 95%CI:0.598-1.312). Conclusions : Herbal medicine intervention can be an effective for treatment in psoriasis. But enhancing levels of evidence, we must try to accumulate clinical researches of herbal medicine to psoriasis in Korea.

Keywords

References

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