Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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Analysis of Risk Factors Affecting Breast Cancer Incidence : Breast Ultrasonography

유방암 발생에 영향을 미치는 위험인자 분석: 유방초음파 검진자 대상으로

  • An, Hyun (Department of Radiology, InJe University Busan Paik Hospital) ;
  • Yang, Sung-Hee (Department of Radiology, Ilsin Christian Hospital) ;
  • Im, In-Chul (Department of Radiological Science, Dongeui University) ;
  • Lee, Jin-soo (Department of Radiology, InJe University Haeundae Paik Hospital)
  • 안현 (인제대학교 부산백병원 영상의학과) ;
  • 양성희 (일신기독병원 영상의학과) ;
  • 임인철 (동의대학교 방사선학과) ;
  • 이진수 (인제대학교 해운대백병원 영상의학과)
  • Received : 2017.06.15
  • Accepted : 2017.08.31
  • Published : 2017.08.31
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Abstract

In general, a number of studies have been conducted on factors affecting breast cancer development, but systematic investigations of risk factors are rare. The purpose of this study was to investigate the factors involved in breast cancer screening before breast ultrasound diagnosis and the risk factors associated with breast cancer screening by ultrasound. Self-administered questionnaire was performed on 417 patients who underwent breast ultrasonography and classified as benign and malignant. Breast cancer was associated with age, BMI, and type of medication(p<0.05). Multivariate analysis showed that the odds ratio was 4.93 times higher in the 50s compared to the less than 50s, 2.43 times higher in the obese group than in the normal group, 0.14 times and 0.16 times lower in hormonal replacement therapy(p<0.05). Therefore, as age increases, periodical examination of health and appropriate weight management are needed. So this study is expected to provide basic data for identification of risk factors affecting breast cancer development.

일반적으로 유방암 발생에 영향을 미치는 요소는 여러 연구가 진행되었으나 위험인자에 관한 체계적인 조사는 드물다. 따라서 본 연구에서는 유방초음파 검사 전 실시하는 건강문진표 작성내용과 실제 초음파 검사에서 유방암 판정을 받은 환자를 바탕으로 관련인자를 파악하고자 하였다. 유방초음파를 실시한 417명을 대상으로 자기기입식 문진표를 작성하였고 양성, 악성으로 분류하여 후향적 연구를 시행하였다. 유방암 발생 관련인자로 나이, 체질량지수, 투약 종류에서 관련성을 보였으며(p<0.05), 다변량분석 결과 교차비(Odds ratio)는 나이에서 50대 이하를 기준으로 50대에서 4.93배, 체질량지수 정상군보다 비만군에서 2.43배 증가하였고 타목시펜과 여성호르몬제 투약 시에는 0.14배, 0.16배 감소하였다(p<0.05). 따라서 나이가 증가함에 따라 정기적인 검사를 실시하고 적절한 체중관리가 필요하다. 따라서 본 연구는 유방암 발생에 영향을 미치는 위험인자 규명의 기초자료로 제공될 것으로 기대한다.

Keywords

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